Bupe Bupe induction not working?? (not PW)

[DustnRoses]

You should be fine, I went 72 hours without dosing bupe on my first week of being on it at 12mg/day. Then I dosed a HydroMorphContin 30, and two OxyNEO 80s while I had the 48 hour window, and I got a little high, but not much. Anyways, as far as going back to the bupe, you SHOULD be fine. Maybe start at a lower dose than bupe if you can, and then wait half an hour or so? But IMO, I think you should be fine as you should still have some bupe in your system.

so you were on 12mgs a day, stopped using for 3 days. For those 3 days, you didn't use anything? Then after the 3rd day, you took the HMC and 2 OC 80s? What is the 48 hour window you're talking about?

I can't remember exactly how long ago I started the bupe. but it was either Thursday or Friday...I think Friday was the last day I did any, and it was in the morning...then I got dope later that day, and it was a complete waste, but I was determined to get high, so I bought another gram the next day, did it, didn't get much better results than on Friday, than yesterday i got another gram, and got 'kinda' high....but now I would like to jump back on the sub.

 

[laCster]

I think your girl took too much sub because she should def feel some relief at a right dose. Too much def causes multiple physical symptoms that could resemble wd especially extreme nausea from suboxone.

I started on 16 mgs, went down to 1-2mgs per day after a month or two, and have felt pretty good from subs. However I do get often nausea spells even after stablizing. The only thing that help me are first generation anti histamines like diphenhydramine or hydroxyzine

 

[Tony Williams]

She took too much bupe 8-16mg the day after Methadone 54mg, no wonder!!!!

Now once you've been stable on bupe, you can stop wait 24-36hr and lets say start on gear >72hr and I've slammed loads in this peroid walked into the pharm and back on 16mg and abit of depression and crapping was it since I already had bupe in me. So when this happens I just get the 16mg at 9pm, come home by the time I feel crap I just GBL asleep.

 

[Soccertrendy]

a few on here have read my statement wrong, i am on methadone, i was saying that held ME not my mrs . I was just trying to give you guys an idea of how much methadone would have held me and if anything i take more heroin than her. She had taken NO METHADONE :D

Strangely she ended up taking some heroin later on that night and it did sort her out. i understand how strange that sounds. but its true.

Shes going to try to get off sometime in the near future hopefully someone on here may be able to help

 

[milagro]

First, I skimmed this thread so this may be redundant information. Additionally, never used H so I do not know about any differences in replacement of any other med other than mine.

I am on an oxy/bupe rotation. I know that seems counterintuitive but that is what my PM doc decided to try rather than up my oxy dose of 120mg/day.

This is my experience with bupe and I am talking about subutex not suboxone. The first time I induced was hell. I was sick for 2 days because the 8mg/day of bupe simply was not doing the trick. I tried waiting longer and reaching higher scores on the COWS but it was always the same. It would take a good 3 days before I began to stabilize on the bupe but I was taking far too much of it during the induction. I would take more thinking that it would help and I am sure most people new to bupe do the same thing.

It does have a ceiling effect and I believe it has a great deal to do with what is being replaced, body chemistry, and how long the prior med/drug was taken. During my first induction I took somewhere around 32mg/day. Essentially, I wasted a lot because the ceiling is typically around 16mg. Anything above that is not going to help most people. That is not to say that it will not help some people. Who knows? There may be a placebo effect but it is an expensive med so wasting it is not desireable.

Anyway, I was getting fed up with the waiting until I felt like hell and I decided to just try and take it ~10-12 hours post last dose of oxy. So I would take a dose of oxy before bed and when I woke up I would begin taking the subutex.

I do not know if my physiology had grown accustomed to the rotation but I had absolutely no Pwds. I would start out taking around 16mg/day and lower it gradually until I got to a point where I could go an entire day without needing it at all. It has a very long half life (mean=37 hours) so once it builds in your system it hangs on a bit.

That is the key. It sucks but I never felt entirely normal until around the 3rd day of induction and by day 7, I was feeling pretty normal. It does not work for BT pain at all. My doc is under some notion that a person can take 4-8mg/day of bupe and use Oxy IR as a BT med. This is absolute crap. My oxy does absolutely nothing for me while on bupe until I have been off it completely for several days and depending on how long I use the bupe it can be up to a week before the oxy begins to work for me.

I have been through this quandry with a different thread and I firmly believe that BT meds can only work when on micro doses of bupe and that means using butrans or, in Europe, Temgesic patches. I am waiting until my next appointment to discuss this with my doc. She really wants me on bupe for baseline pain but insurance will not cover it unless I go through the whole pre-approval BS.

Sorry to the OP for getting a little off topic but I find through reading many posts, speaking with physicians, and pharmacists(usually completely ignorant about bupe) that the efficacy depends a great deal on many factors. Trial and error have gotten me to a point where I feel pretty comfortable switching from one to the other without the dreaded PWDS. In fact, I can now switch with very few WD symptoms.

I am not preaching that my experience be gospel simply that it takes some experience using bupe effectively and it isn't a magic bullet that is going to alleviate all WD's right away. Good luck