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  • BDD Moderators: Keif’ Richards | negrogesic

Bupe Bupe barely works

So some updates, today is day 3, and I had only 2-3mg of bupe left. Took it in the morning, again, didn't feel 100% ok (still have temperature fluctuations, stomach cramps and diarrhea, weakness and some discomfort) but it's not that bad.
Also I did add kratom, used 2 teaspoons with morning bupe and 3 ts now, and it definitely helped.
My working theory with bupe is that it's wonderful for satisfying the opioid receptors in the brain but not so much for the ones in the body. I notice your symptoms are all related to physical effects and not the truly horrible part (the mind screaming for MORE). In other words it's just enough to keep you from running out right now to score more real dope but it can't cover the the loose bowels and feverish effects of w/d. At least not in someone that has a large habit. Your body is simply too used to compensating for having all that morphine floating around in it and it will take time for it to adjust to living without it no matter how much bupe you manage to get across the blood brain barrier.

I've also personally found bupe to not be that great for w/d in general. At least not for someone that's already actively addicted to better opioids. Indeed most people use it as a band aide to make w/ds just bearable enough that they can work or hide w/d from people around them for just long enough to score/use again. It's not a magic bullet like it's sometimes played up to be by the medical industry and people that have claimed to be "saved" by it. Its only redeeming features are that 1) it's legal depending on your situation and if you can pay and 2) it lasts just long enough that you don't wake up in the middle of the night in full blown withdrawal. I guess from a salesman point it also has another thing going for it which is 3) it hasn't earned the same reputation as methadone among the general population yet. Meaning people don't joke about it being "junkie juice".

I am of the opinion that this drug is only used for 'treatment' because there is still a patent for certain formulations. In other words I don't buy into the hype I guess. I have used it in the past myself don't get me wrong. But mostly out of desperation and the simple fact that there was nothing better I could get my hands on at the time. I feel that most people taking it to treat addiction would be far better off using almost any other opioid in some kind of formulation that would hold them all day. Of course, a lot of those formulations end up being the exact type of things people seek out to get high from assuming they can defeat the time release mechanism. As we saw in the past with so many ER morphine and oxycodone formulations.

That said, opioids like oxycodone and friends are certainly much easier to manage, are probably less harmful to the user long term (assuming they take it as intended) and are far easier to taper/quit once treatment is supposed to come to an end. Bupe on the other hand and its friend methadone are horrible to taper and quit once you've been established on either long term. They also cause a bit of a perma-tolerance that makes other opioids less effective after you cease using them. They are the perfect type of drug to give someone you plan to have coming back to spend $200+ every month and in 'treatment' for the rest of their lives.

There is also this strange edge with bupe that I dislike. By that I mean it doesn't provide typical opioid euphoria. In fact, in my expereince with both my own use and people using around me I've seen it regularly cause people to fly into fits of rage. It has this uncanny ability to make people become very angry. It also seems to rob them of the ability to feel real joy from most any kind of activity happening in their lives. Subjective I know. But I'm convinced it causes negative emotions and states of being in most people. It isn't just the loss of their preferred opioid/high causing this either. It happens with totally opioid naive individuals using bupe as a cheap high. Methadone has a similar way of making you very very depressed. But it isn't as profound as what bupe does and methadone is at least somewhat sedating. Bupe is like all the bad things about opioids with none of the good.

I am not surprised you feel bad though. Even if bupe didn't have the above problems you were taking 600+mg of morphine a day. That's enough to kill most people walking around on the planet and you were taking it daily. No matter what you do you're going to feel pretty awful for a little while. You're fortunate that you're able to get out of bed at the moment.
 
I am not surprised you feel bad though. Even if bupe didn't have the above problems you were taking 600+mg of morphine a day. That's enough to kill most people walking around on the planet and you were taking it daily. No matter what you do you're going to feel pretty awful for a little while. You're fortunate that you're able to get out of bed at the moment.

Well, with bupe I didn't feel that bad, shitty, but it was nothing compared to cold turkey. Also, surprisingly, kratom helped pretty well from day 3 (with 3mg of bupe). With kratom, I basically don't feel any wds and can sleep for 5-6 hours. I do feel a lot of side effects from Kratom tho.
And btw, morphine is used as a maintanance drug, and most people are prescribed 1000-1200mg a day. Morphine has pretty low oral BA.
And I never felt anything less than 200mg, even when I didn't use and had no/little tolerance. (and I could feel 300mg of codeine - equivalent to 30mg of M. and get a decent high)
My theory -because it's hard to completely destroy slow-realease mechanism.
Anyway, it was my mistake to take such a high doses of Morphine.
 
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