Opioids Buccal bioavailability of Suboxone/buprenorphine?

[Båtmannen]

Hello

I've recently started my buprenorphine treatment. At the moment I'm on 2 mg of buprenorphine and 0,5 mg naloxone. Tomorrow I'm getting 4 mg buprenorphine and 1 mg naloxone.

They watch me when I take it, and I have to drink afterwards, so there's really no chance of getting it out to plug, insufflate or shoot it. Therefore I'm wondering if I'll get better or worse effect by taking it buccal instead of sublingual.

I have searched but I really didn't find any good information on this.

What do you think? Even if you don't know: have you tried taking it through the buccal ROA? Is it the same as sublingual, better, or worse?


best regards

 

[SS373dOH]

buccal ba isnt as high as sl.. you can try the 'mouthwash' or 'alcohol' method, to try to increase bioavailibility..

 

[Båtmannen]

buccal ba isnt as high as sl.. you can try the 'mouthwash' or 'alcohol' method, to try to increase bioavailibility..

Thanks.Ithinkiwill.

 

[kleinerkiffer]

http://jat.oxfordjournals.org/content/20/6/369.full.pdf

Sublingual bioavailability was esti-mated at 51.4% (range, 12.8-92.2% ), which is in excellent agreement with theprevious work by Bullingham et al. Buccal bioavailability, although not significantly different, was less than sublingual bioavailability (27.8%; range, 4.1-42.7% ).

Check out this thread for more info http://bluelight.org/vb/threads/404...-Sublingual-Use?highlight=suboxone+sublingual