As I've been scouring the Bluelight Neuroscience and Pharmacology forums looking for more information on this compound, I've come across a few threads talking about some apparent hepatoxicity..
This information was being reported after a rat study was unearthed wherein six rats were set to differentiate BTCP from saline.
It looks like one rat died, and the other five rats ended up in a bad way, with lost weight and abdominal tenderness.
Necropsies performed on the rats linked these effects with gastrointestinal issues like
adhesive peritonitis linked to mesenteric lymphadenopathy, as well as ileitis, and encapsulation of the liver.
So the researchers lowered the dose, but subsequent groups of rats suffered the same consequences, even up to death, after prolonged and repeated exposure.
The initial dose used in the studies was 10mg/kg, and the adjusted dose was 5mg/kg. A Bluelight user 'any major dude' did the math for rat to human equivalence and worked out that this would translate to approximately 50mg doses for humans.
So it would seem that the safety margins for this drug would be very thin.
Of course, the hepatoxicity only occurred with repeated administration.. There was talk that this could be used without too much risk, but only sparingly. 'Vecktor' even mentioned that he personally knew a few people who had tested the drug up to 25mg with no subjective negative effects.
In the same thread, there was some discussion regarding the SAR of this drug, and it seems like this may be a more potent DRI than cocaine, lacking activity at the serotonin and norepinephrine sites.
Also, somebody mentioned that the metabolites are also known, but I can't find any further discussion about that..
I'm going to keep reading up on this drug.. Maybe Google Scholar will turn up some more information.
I'll leave the link to the thread where I found these conversations..
Supposedly this material has appeared on the market, there appears to be a lack of even basic research literature search by those promoting this substance. this thread is for discussion of the science anything off topic will be deleted. This on the face of it does not look good, especially for...
www.bluelight.org
I don't mind being the lab rat usually, and I am still interested in testing this drug, but it looks like this is going to be a risky business.