Opioids Boosting / potentiating opioids with loperamide (Immodium)

[Opana Man]

I was taking some Oxymorphone today and thought about an idea. Now we are all probably aware that there are different ways to boost the duration or strength of opioids correct? I normally uses diphenhydramine or hydroxizine but thought today about another idea.... Loperamide! Now everyone on here argues over whether or not loperamide crosses the blood brain barrier, everyone also knows there are Mu receptors in the gut. If loperamide's bonding affinity is so high then perhaps they would fill the guts receptors and allow more Oxy to attach to the brain's receptors. I was wondering if anyone has tried this before? Can anyone recommend better potentiaters to use? The community has discussed this before but I didn't see anything on loperamide.....

 

[amapola]

Hi Opana Man,

I edited SWIM from your post for clarity and changed the title to reflect loperamide. Here is The Ultimate Opiate Potentiation Thread v2.0 which you can use for discussion on anything besides loperamide which I think would be fitting for it's own thread at least for the moment.

 

[Opana Man]

I wonder if, by takig immodium (Which occupies the gut Opioid Receptors) it frees up Opioids that would normally attach there to go to the brain and central nervous system?