Boiling suboxone to get rid of naloxone?

[DarthCaedus]

Seems to work, for iv that is, anyone ever tried this? naloxone is destroyed at lower temperature than bupe. not full boil, just til bubbles began to surface

 

[Alex000]

No need to destroy the naloxone. Doctors and pharmaceutical companies will tell you that naloxone means you can't IV a Suboxone preparation, and this is just wrong.

 

[Pjkt2501]

^ That's been what I hear everywhere. Haven't ever done it myself, but Buprenorphine has a higher u-opioid receptor binding affinity than naloxone, so it doesn't cause an issue.

I can't guarantee that 100% of people will be problem-free. Heating the solution is never the right way to go dealing with opioids however.

 

[opiatekrzy]

honestly, i think the naloxone prevents you from feeling the initial rush from bupe when you inject it as when you IV subutex you feel that blanket and subtle rush within seconds or a min later, when IVing suboxone i noticed i dont get that rush like i do with subutex, i just notice the bupe buzz 30mins later without a rush..in my experience, it seems naloxone just puts a blanket over the buzz bupe gives u to a degree when IVed

 

[Tripman]

I imagine you'd need to do an A/B dual solvent extraction method... I can't see you being able to get the temperature right to destroy the naloxone entirely and none of the bupe outside of a laboratory setting.

 

[Pjkt2501]

^This. I googled "naloxone vaporisation temperature" and the second result states that it's double the BP of water.

So to say, naloxone vaporises at 200-205*C, where water boils at 100*C. You aren't coming close to removing the naloxone when you do what you're doing - you're just moving it into the shot faster / more.