I switched from heroin to methadone. This time I had really big problems with it and was still using heroin although I drank my methadone.
So I started injecting methadone. My plan is injecting methadone for the first days and then switch to drinking and then reduce the dose.
Until now, I seems to work. This way I was able to switch to methadone without taking heroin, too. Now after some days, I think I am stable enough to switch to drinking my methadone.
But now I thought of bioavailabilty. I read a study about people smoking and injecting heroin. And withdrawal was much more severe in heroin injector than in smokers although they took same doses. This was because injected heroin had a 4 times higher bioavailability than smoked heroin.
What with methadone? In the end I will feel it by myself, if I will need more methadone when I drink it instead of injecting it. But I am looking for some medical information or clinical studies. Polamidon is not only used as a heroin substitute but also as injectable pain killer. So I think there must be information on that. But I couldn't find anything.
I even don't know if methadone/L-methadone (polamidone) has a high first-pass-effect.
Is dose increase needed when someone switches from injecting methadone to drinking methadone?
Is there a difference how long the effects will last between those two consuming methods?
Any information? Information for doctors, clinical/medical studies - That would be the best. But if there is nothing to find, maybe someone can write about his own experiences.
So I started injecting methadone. My plan is injecting methadone for the first days and then switch to drinking and then reduce the dose.
Until now, I seems to work. This way I was able to switch to methadone without taking heroin, too. Now after some days, I think I am stable enough to switch to drinking my methadone.
But now I thought of bioavailabilty. I read a study about people smoking and injecting heroin. And withdrawal was much more severe in heroin injector than in smokers although they took same doses. This was because injected heroin had a 4 times higher bioavailability than smoked heroin.
What with methadone? In the end I will feel it by myself, if I will need more methadone when I drink it instead of injecting it. But I am looking for some medical information or clinical studies. Polamidon is not only used as a heroin substitute but also as injectable pain killer. So I think there must be information on that. But I couldn't find anything.
I even don't know if methadone/L-methadone (polamidone) has a high first-pass-effect.
Is dose increase needed when someone switches from injecting methadone to drinking methadone?
Is there a difference how long the effects will last between those two consuming methods?
Any information? Information for doctors, clinical/medical studies - That would be the best. But if there is nothing to find, maybe someone can write about his own experiences.