Digging up an old post here, but I have a quick question or two for anyone who can answer.
If I am reading this correctly, the consensus is that we are not seeing more beta keto substituted PEA's (other than the stimulants and the entactogens) because the synths would be considerably harder (if not impossible?)
I was really trying to find some information on things like beta keto TMA-2, which (at least from the perspective of a novice) would appear to be straightforward. Could bk-TMA-2 not be synthed with TMA-2 as a starting point with some reasonable yield?
Does anyone know if any of these are known and active? (other than the shulgin quote earlier in the thread.) I was afraid perhaps we were not seeing any bk-DOB or bk-2c-B because the ketone did something to destroy HT receptor affinity and they lacked activity.
It would be nice to see a published result somewhere just to know that it was possible. Perhaps one of these days...?
BK 2CB and BK DOB are known creatures both are well down on potency and given the evil cardiovascular effects of beta hydroxy analogues of psychedelic PEA's which would be among their metabolites they are essentially dead. Glennon made them in 2003 from memory.