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Best Weight Loss Drug

Smyth

Smyth

Bluelighter
Joined
Nov 10, 2004
Messages
2,157
Location
England
What is the best weight loss drug?

I managed to lose weight on sibutramine but my weight is still 91kg, 16kg heavier than the target weight.

I have some stuff here called "Hydroxycut Hardcore X" that is laiden with caffeine. This seems to be helping matters. For example, see the following article.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923369/pdf/CN-8-149.pdf

For my next drug I was considering clenbuterol.

What are other peoples suggestions? (bearing in mind I dont want to lose too much sleep)

I just want drug suggestions, not a bunch of info on calorie restriction and exercise.
 
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I took 10g of modafinil I got from a body builder supplier va few years ago. I seem to recall it working well as an appetite suppressant although I was not overweight at that time.
 
Best weight loss drug

Amphetamine!

also would like to second modafinil, I personally do not react well to it, it is great for appetite suppression though

clenbuterol, I wouldn't recommend. it can be pretty effective especially in combination with other appetite suppressants but that puts a lot of stress on the heart
 
hCG (injectable) is quite surprising. I took it for other reasons, but I've administered it to patients who routinely drop 15-25 lbs during roughly a month's time. 125 IU IM QD in the glute or sartorius area
 
amphetamine is great, but I'd actually say lisdexamfetamine. It's a much smoother feeling, and lasts forever, which is definitely better than bi or tri daily dosed drug, you don't want one wearing off when you're sitting around the house watching TV at night eating ice cream.

I don't recall modafinil having any anorectant properties, but I'm not surprised to see people suggesting it. If it's not scheduled there it's widely available, and makes good sense.
 
Hammilton said:
amphetamine is great, but I'd actually say lisdexamfetamine. It's a much smoother feeling, and lasts forever, which is definitely better than bi or tri daily dosed drug, you don't want one wearing off when you're sitting around the house watching TV at night eating ice cream.

I don't recall modafinil having any anorectant properties, but I'm not surprised to see people suggesting it. If it's not scheduled there it's widely available, and makes good sense.
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SWIM lost 3 stone in two weeks after a 2-dpmp. Side effects of extreme paranoia, best being a voiced told me I was a threat to democracy.
 
not a drug but fresh juice fasting is a healthy quick way to lose weight and the stomach shrink means you will not feel hungry. all you need is to buy a juicer
 
Pyramid T3 followed by a month on your fav stim (tapered down) till TSH levels renormalize. Human growth hormone or better yet a GHRH (CJC1295) + GHRP will also help by altering insulin resistance. Keep the carbs down (if you want to be really hardcore you could use insulin to induce hypoglycemia - NOT recommended). If you are really really in a hurry - DNP (again NOT recommended) would be the fastest, most dangerous way to lose weight.
If you are a dude consider a low dose of a mild androgen along with this (maybe anavar) to prevent excess weight / muscle loss from the T3.
 
most amps are catabolic i believe....which will break down muscle as well...go on an EC stack it will suppress appetite, prevent break down of your muscles, and raise your metabolism
 
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That is a fantastic delusion.
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This is exactly the same sort of side-effects I have been having while on stimulants. After taking too much sibutramine I could not sleep for three days and was hearing voices (in my head) from people saying to me "we're here to kill you" calling me "the loserist loser" etc.
 
Smyth said:
This is exactly the same sort of side-effects I have been having while on stimulants. After taking too much sibutramine I could not sleep for three days and was hearing voices (in my head) from people saying to me "we're here to kill you" calling me "the loserist loser" etc.
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Voices are classed as hallucinations but yes, my delusions usually demean me as well. I was impressed by the poster having a firmly-held belief that he personally is an obstacle to the freedom of a nation. I think I would covet that symptom.

Anyway, back on topic: the FDA recently delayed an application for a bupropion + naltrexone cocktail to be marketed as a weight-loss drug because cardiovascular safety had not been established. Nevertheless, the cocktail outperformed placebo by a good margin. I think subjects lost an average of 5% of their body mass over a long period of time.
 
The only thing that ever caused prolonged weight loss for me was eating less or eating different foods, not drugs. So, as far as I'm concerned, there is no best weight loss drug; they are all ineffective.
 
Ephedrine + Caffeine is by far the best combination known. Too dangerous, though. I used to use salbutamol + caffeine with some success. It was my choice because it was extremely cheap and more safe.
 
mrdocat said:
Ephedrine + Caffeine is by far the best combination known. Too dangerous, though. I used to use salbutamol + caffeine with some success. It was my choice because it was extremely cheap and more safe.
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Haha, I remember those days. Would pop a few 8mg ephedrine tabs + drink a large coffee when starting work. Gotta say, it really does make you more focused and productive. At times, it felt like mild speed - which is to be expected considering ephedrine and/or pseudoephedrine are used to synthesize meth.

Also, I never realized salbutamol helps with weight loss. I recently had it prescribed to me (along with zithromax - which I gotta say is the most effective antibiotic I've ever used and I've used quite a few) because of a severe case of bronchitis.

Edit - Sorry for bumping your month old thread.
 
4-FA works very well for weight loss. It does have certain side effects but is not a "bad" stimulant.

I found it easy to miss a whole day without eating anything at all and other days where my calorie intake was greatly restricted. This worked very well indeed to reduce my weight although I still weigh 87kg.

I dont even eat those caffeine pills because I would rather drink coffee than overdose on caffeine.
 
Ethcathinone or aephetamine (phenylisobutylamine) -- selective norepinephrine releasers, which means less unwanted stimulation and no crazy delusions.

I don't know if either is available on the grey market, though.

Otherwise, nAChR agonists and indirect agonists (nicotine, cytisine, lobeline, cotinine) and histaminergics (modafinil, betahistine) sound safer, from a mental standpoint, than your typical stimulant derivatives. Smoking tobacco is of course not recommendable.

Cannabinoid antagonists have also been considered as potential anorectics, as have 5-ht2c agonists; however, both of these have generally been found to cause a lot of unwanted side effects. I'm sure several bluelighters are familiar with the latter case (eg. mCPP).

I should say that weight "loss" (really: management) is a long-term affair, and that it is essential to develop responsible eating habits and to learn to handle one's appetite soberly.
 
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