Benzos of abuse

[haribo1]

Well, an -OK or C=O- group at the 3 position gives rise to isomers. How about a 3 methyl group? It HAS been done, but I don't have much information.

 

[getreal]

Are you sure about that? Think............

 

[Ham-milton]

No idea what a 2'-nitro would do though, my guess is that it might be too bulky and ruin activity entirely, but you never know, it could be a winner...

You're probably right, but according to the SARs paper I read, you need an 8 or 9- halo group, but obviously a nitro group works just as well, if not better for recreational purposes, I assumed that it would work well in the other position that putting a halo seems to make benzos more recreational, the two.

Who knows, benzos are so open to different substitutions. They're almost impossible to make inactive! well... that's a bit of a stretch.

 

[Ham-milton]

This is called Flutoprazepam, a benzo I'd never heard of before. It's apparently the most valuable benzo in Japan, where benzo abuse is rampant. Not surprising- you can only imagine that a culture that pushes everyone so hard would end up with rampant anxiolytic abuse.

Sweet name, though. It doesn't seem that interesting, besides the cyclopropylmethyl group which I've never seen on a benzo before.

There doesn't seem to be any special pattern to making benzos more recreational or less. You can tack on any of a dozen different groups and end up with a benzo that somewhere will be tops.

Us, we've got Xanax; Bali, nimetazepam, Japan, plutoprazepam (we all know that's a better name), I think temazepam was or is tops in the UK (no?)...

 

[Schamane]

i very liked cinolazepam, it made vision dizzy on other benzos its normaly clear

 

[Jamshyd]

The main problem with measuring a benzo's recreational value is that it seems that certain different people seek more of some of the many facets of the benzo experience than the others.

So for example, it seems to me that for many people, amnesia and sleep are fun, that is why alprazolam, midazolam, and flunitrazepam are very popular and I personally fail to see why. Personally, I seem to be after the muscle-relaxant properties.

I recently got to try Etizolam, which belongs to a new class of benzos known as "thienotriazolodiazepines". It is most closely related to the more well-known brotizolam (which is also a favourite).

I have to say, although rather light, this benzo is more recreational than any other I have tried. It provided a nice warmth and mood-lift not unlike opioids.

I have read somewhere that this drug posesses additional effects on norepinephrine reuptake. This could be the reason.

I wonder what other benzos with similar chemistry are like?

ps. Did i mentioned that both abovementioned drugs were prescribed to me in japan? I think Japan has found itself a niche in the drug world as exotic benzo central!