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Benzos Benzos and Diphenhydramine

Thomas29

Bluelighter
Joined
Oct 25, 2010
Messages
1,505
Is it safe to take 100mg Diphenhydramine I use to sleep at night with a reasonable dose of Benzos?
 
From personal experience, yes. Well, what do you mean by 'reasonable dose'? This combination can fuck you up....in a good way ;)

Fuck,, i know this isn't what you're asking, but diazepam and diphenhydramine is possibly the best drug combo I've taken. The valium relaxes you enough to get rid of the god awful paranoia (spiders) that diphenhydramine cause. ~50mg diazepam and 300mg diph was one of the best drug experiences i've ever had. I was so fucked i could barely speak. Which to me isa good thing. No paranoia, just utter inebriation. If that's your thing, it's a fucking wonderful combo.
In the interests of harm reduction however, bear in mind that DPH increases the heart rate. I learnt the hard way that DPH is an awful drug for bringing you down.
 
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Ya I know it raises your heart rate but it also seems to make me sleepy enough to just fall asleep. I do not quite understand how that works something to do with the H1 Receptors or some.
 
Ya I know it raises your heart rate but it also seems to make me sleepy enough to just fall asleep. I do not quite understand how that works something to do with the H1 Receptors or some.

Do you get that tightness of throat when you take it? If i take 300mg+ I can barely speak...which for some reason i enjoy. ANyway, how much benzos were you thinking of taking?

I took amt recently, and i gotta say, I've always had more fun on DPH.

But as a hypnotic, i find it more effective than Z-Drugs and benzos. But each to their own.
 
No idea which Benzo but equivilant to 1mg at least of Clonazepam at most 3mg I basically have little to no tolerance. Also can I mix a no more than 2 beers with it I tried googling and could not find anything specific the package says to just avoid Alcohol.
 
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OK well off the top of my head i have no idea of Clonazepam's potency compared to that lovely gold standard of benzos, Diazepam. But for a good time i take ~300mg DPH and 50mg diaz. I don't even need to look at a benzo conversion chart to know that that's more than you're taking. However you said you we taking it for sleep, which undoubtedly raises more risks (eg chokin' on your vom). Not safe. But i dunno....I've passed out on 500mg Nitrazepam and 2000+mg pregabalin and been ok (fuckiing reckless). Go look up some benzo conversion charts. Many may disagree, but I think you''d probably be fine. Other posters please feel free to prove me wrong.
 
I will also be taking GABAPentin 1200mg or less. Basically what I want to know is with this low-dose combination is there even a POSSIBLE RISK of just dying and not waking up I will not do it but if it is just a risk of like sleep walking and stabbing random people that shit don't phase me LMFAO ROFL.
 
Idk the Benzos work but it works even better with the DPH I guess I just go with the flow. The question I am asking is this dangerous to the point of possible fatality I do not care if it floats your boat or not it terms of effect.
 
So the thing about diphenhydramine is that if you want sedating relaxing effects it's best in lower doses, like 25-75mg. That will give the most pronounced anti-histamine effect, which is responsible for sedation, calming, and allergy relief, etc. If you take too much, it becomes more stimulating, because it also has anticholinergic and SNRI properties, which start to cancel out the sedating/relaxing effect. In low doses you don't really get the anticholinergic and SNRI effects, as diphenhydramine has a higher affinity for histamine receptors. So basically less is more. I find 25-50mg a good dose for sleep.

I assume whoever said it raises heart-rate and is an "awful drug for bringing you down" took too much.

Taking diphenhydramine with a benzo is considered relatively safe, doctors will prescribe them together. It is just going to increase the sedation etc, assuming you're not taking an enormous dose of the benzo I think it should be fine.
 
Although if you can get to sleep just with benzos, do so. I find that diphenhydramine leave you feeling groggy for ages in the morning and your mouth dry all day.
 
Do you get that tightness of throat when you take it? If i take 300mg+ I can barely speak...which for some reason i enjoy. ANyway, how much benzos were you thinking of taking?

I took amt recently, and i gotta say, I've always had more fun on DPH.

But as a hypnotic, i find it more effective than Z-Drugs and benzos. But each to their own.

I had recently been in a habit of shooting about 125mg of DPH every night to sleep. The ''rush'' is just as you put it - it feels like you're choking... sort of. (But in a good way? Hard to explain.) How odd a sensation.
 
I made a thread about this a few days ago and yes its fine to mix the two. I would suggest taking a lower dose of the DPH like another poster said. For some reason, lower doses cause more relaxation than higher
 
What about mixing Opioids/Opiates with Diphenhydramine is that as dangerous as mixing Opis and Benzos particularly for sleep since your breathing slows even more in that state.
 
What about mixing Opioids/Opiates with Diphenhydramine is that as dangerous as mixing Opis and Benzos particularly for sleep since your breathing slows even more in that state.

What opioid? Diphenhydramine affects certain liver enzymes which can increase/lengthen or decrease the effects of specific opioids. But in general I would say no it's not as dangerous as benzos+opioids.
 
It should be perfectly fine and relaxing as long as you are used to benzos, although In my experience its crazy hard to get out of bed the next day. Like my alarm will be blasting for 30min and I wont even here it. Someone with no benzo tolerance will probably suffer from this combo. (unless your only talkin like 0,5-1mg xanax or some equivalent)
Also probably not a good habitualy do this...once in a while for a nice escape is fine but if your doing it everynight to sleep it will be negative as with most drugs.
 
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