Why does clonazepam seem to be the preferred benzo for treating TN? Does it have properties other benzos don't? I find bromazepam better for anxiety but i dont want to switch all the way if it's gonna risk making my TN worse
N&PD Moderators: Skorpio | someguyontheinternet
Im intolerant to both the only thing that i can get in Canada to help my TN is morphine.TN is usually well-treated with Tegretol and Trileptal. Clonazepam doesn't have much research to back it up. I mean I couldn't find any studies suggesting its use, just a note on the wikipedia page. Sounds super painful though. My sympathies, such as they are.
You tried lamotrigine, baclofen, topiramate, levetiracetam, gabapentin, pregabalin, cannabinoids, eslicarbazepine, brivaracetam, lidocaine, misoprostol, phenytoin, fosphenytoin, pimozide, sodium valproate, sumatriptan, tizanidine, tocainide, tricyclic antidepressants, vixotrigine and botulinum toxin-A?Im intolerant to both the only thing that i can get in Canada to help my TN is morphine.
You tried lamotrigine, baclofen, topiramate, levetiracetam, gabapentin, pregabalin, cannabinoids, eslicarbazepine, brivaracetam, lidocaine, misoprostol, phenytoin, fosphenytoin, pimozide, sodium valproate, sumatriptan, tizanidine, tocainide, tricyclic antidepressants, vixotrigine and botulinum toxin
Yes, clonazepam is superior to other benzos as an anticonvulsant, I think that's why they choose it.
What I found to be effective (to a degree, as everything else when it comes to TN) is lidocaine: I wear a pumpimg device for a week every 3 months. I have to be on other meds that @AlphaMethylPhenyl and you listed above, but this lidocaine treatment is helping for sure. I suggest you to read about the subject and ask your doctor if she/he knows about this procedure being performed in your area or not. And, of course, feel free to PM me if you have any question about how it feels wearing it or whatever
Clonazepam has muscle relaxant properties. I’m prescribed both clonazepam & a small amount as needed xanax. Both are prescribed for severe PTSD. But the clonazepam helps my neck & jaw issues where the Xanax does not.
I don’t know if that helps any but … for sure some benzos will help more with body/muscle relaxing properties than others
Big hug![]()
My father-in-law has TN. It's caused him to need multiple intercranial surgeries, none of which has been particularly effective. He's been on just about every drug you can think of for it. It's still more or less debilitating. The only thing that he said helps him is gabapentin.
Probably blocks Na+ VGICs too, I'd guess.I always hear people saying that clonazepam blocks calcium channels, which is why it is the first choice anticonvulsant benzo, but it seems to block calcium channels at a thousand fold higher dose than the interaction with GABA receptors. I would be surprised if this affinity contributed to its therapeutic effects, unless there is some missing factor that either renders the receptors more facile to opening or increases the local concentration of clonazepam at those calcium channels.
I've never seen any references to this, but it could explain some things.Probably blocks Na+ VGICs too, I'd guess.
I have 'fake pain' due to autoimmune sclerotic plaque in the brain immitating peripheral neuropathy and sometimes neuralgia type pain at TMJ/Trigeminal area.TN is usually well-treated with Tegretol and Trileptal. Clonazepam doesn't have much research to back it up. I mean I couldn't find any studies suggesting its use, just a note on the wikipedia page. Sounds super painful though. My sympathies, such as they are.
autoimmune sclerotic plaque
Not related to blood vessels. Not a vascular cause at all. I sent you a PM.WTF? I knew there was something to this. Maybe that's why I have screwed up hearing. Yep. Vascular causes, impeding blood flow to the ear. Yep. I knew this as soon as I read it.
TN is usually well-treated with Tegretol and Trileptal. Clonazepam doesn't have much research to back it up. I mean I couldn't find any studies suggesting its use, just a note on the wikipedia page. Sounds super painful though. My sympathies, such as they are.
Just that I was under the impression that benzos probably inhibit glutamate much more than NE. For that there are beta blockers.
Your sources are just about antiquesTrigeminal Neuralgia | New York Headache Center
nyheadache.com
Clonazepam has been reported to be effective in two thirds of patients with TN (17,18,19).
I copied and pasted the relevant citations.
17. Chandra B: The use of clonazepam in the treatment of trigeminal neuralgia. Mod Med Asia 1975;11:8-9.
18. Court JE, Kase CS: Treatment of tic douloureux with a new anticonvulsant (clonazepam). J Neurol Neurosug Psychiat 1976;39:297-299.
19. Smirne S, Scarlato G: Clonazepam in cranial neuralgias. Med J Aust 1977;1:93-94.