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Benzodiazepine Raw Powder Solubility

CaptainBenzo

CaptainBenzo

Bluelighter
Joined
Oct 21, 2008
Messages
60
Greetings,

Since the Benzo's are lipophilic (Not water soluble) I'm trying to figure out a way to make them soluble. What I've been doing so far is breaking down the crystalized powder in Ethanol (Everclear 190 proof). Which works great as far as consuming the desired dosages.
However its not always practical to carry a liquid (Although I've made it convenient by putting
it in a vial with an "eye" dropper)

My goal is: I would like to get it into a capsule form.

My question is: Edit...I didn't read the "sticky" on drug synthesis

My statment is: I'm trying to figure out what what hydrophilic (water soluble) intermediate I
should use, maize starch, sodium starch glycollate, or just lactose.

=D Dutch
 
Last edited:
How long do you need to have it filled in advance?

If you could fill a ml in a capsule with gelatine powder it would make it viable for a day or two I think. At least that's what I find when I search on google :)
 
Couldn't you dissolve it in the ever-clear then just evaporate off the ever-clear or would that leave you with the powder again or some other form of the drug?
 
Temeraroius said:
Cant you just put some of the powder in capsules?
Click to expand...

Like I was stating benzos aren't water soluble. So they need additives like most drugs I.E. Oxycodone Hydrochloride. The Hydrochloride (HLC)(Basically a salt) is what makes Oxycodone water soluble, by this I mean you can consume the drug just as it is because of the HLC. You can shoot it, sniff it, shove it, or swallow it. Another good example it Cocaine, also contains a Hydrochloride form other wise you wouldn't be able to consume it as stated above. Freebasing is basically removing those salts and fillers (cut).

I'm not sure way, but the benzo raw powder is just that, pure drug and thats the way its purchased. As Oxycodone can be purchased with the Hydrochloride acids/salts already added. I wish there was a alprazolam hlc, life would be alot easier for me and this thread wouldn't exist.

:\ Dutch
 
mukaki said:
How long do you need to have it filled in advance?

If you could fill a ml in a capsule with gelatine powder it would make it viable for a day or two I think. At least that's what I find when I search on google :)
Click to expand...


Thats where preservatives like colloidal anhydrous silica come into play. Prolongs the "self life" of gelatine, starches, lactose etc.
 
-Temeraroius, interesting theory however I believe the Everclear would evaporate rapidly and you'd be left with a small amount of residue in the bottom of the bottle.

-Slay, are you sure midazolam is hydrophilic?? Do you have any info supporting that?? I'm very interested

:)Dutch
 
my knowledge about chemistry is limited but i know its water soluble (try googling it, tons of results about its water solubility)
 
CaptainBenzo said:
-Temeraroius, interesting theory however I believe the Everclear would evaporate rapidly and you'd be left with a small amount of residue in the bottom of the bottle.

-Slay, are you sure midazolam is hydrophilic?? Do you have any info supporting that?? I'm very interested

:)Dutch
Click to expand...

When extracting DMT, a similar process is used where you more or less dissolve some processed plant matter in naptha (evaporates) then you let it evaporate and the residue left over is the freebase form. Also when making a marijuana tincture, the thc is dissolved in ever-clear then the ever-clear is evaporated and you are left with hash oil. Could work, might not, or you might just be left with what you had before. I think that ideally you would need to put it into solution with something to make the HCl bind to it then have it evaporate off leaving you with the freebase form, like with DMT extraction. If your benzos are in aqueous solution I dont think they would evaporate off with the everclear would they?
 
so this is a "how can I get my bulk benzos ready for sale?" thread?

I think that ideally you would need to put it into solution with something to make the HCl bind to it then have it evaporate off leaving you with the freebase form, like with DMT extraction. If your benzos are in aqueous solution I dont think they would evaporate off with the everclear would they?
Click to expand...

WAHHH? No, your benzos will not evaporate with the ethanol. What is this 3rd grade chem??? Tommorow we'll be learning what happens when you mix vineager and baking soda in a volcano looking thing. O-M-F-G as I like to say.

And for the most part, benzos won't form salts (that HCl thing is part of the molecule, mind you).
 
I know it has to be part of molecule I am not retarded. I know it has to form a salt so that it can be polar and go into solution. I was simply stating what i thought might be possible and I didnt even say I was sure of it so dont flame. Is it not okay for me to know less about chem than you?
 
But if we start there, soon it'll be flying and then driving then read and righting, and soon enough, you'll be hiring me to invade poland and set up your death camps, and you can't afford my rate.
 
Hammilton....Always blowing up my spot, wait until I have enough posts to private message you.
You'll know who I am, until then please keep that sarcastic shit to yourself.
Were are not all in college for chemistry like you. We are here to learn because of this. Not to make ourselves feel superior to people who know less about that subject. Please use your knowledge to help people learn without trying to lower our self esteems

8)Dutch
 
CaptainBenzo said:
Hammilton....Always blowing up my spot, wait until I have enough posts to private message you.
You'll know who I am, until then please keep that sarcastic shit to yourself.
Were are not all in college for chemistry like you. We are here to learn because of this. Not to make ourselves feel superior to people who know less about that subject. Please use your knowledge to help people learn without trying to lower our self esteems

8)Dutch
Click to expand...

Couldnt have said it better myself.
 
kidamnesiac said:
then go to basic, this forum requires at least a semester of P-Chem (read the rules)
Click to expand...

I read the fourm rules, no where did I see that. I don't need a semester of P-Chem to have an intelligent conversation about this topic. I've done enough research to be here.The original topic however was in violation of the synthesis rule and this thread WAS beyond basic. Now seems to be just a waste of bandwith

:\Dutch.....Moving on to something more productive like solitare
 
dissolve it in alcohol, pour as a liquid onto whatever solid powder you want (it doesn't fucking matter), stick into a mixer or mix like hell by hand, let dry for a while, cap with a cap'm'quik, sell to all your buddies. got it? NOT ADVANCED.
or just lay on blotter and pick up from the distribution part. want us to help sell any other drugs for you?
 
CaptainBenzo said:
-Temeraroius, interesting theory however I believe the Everclear would evaporate rapidly and you'd be left with a small amount of residue in the bottom of the bottle.

-Slay, are you sure midazolam is hydrophilic?? Do you have any info supporting that?? I'm very interested

:)Dutch
Click to expand...

Midazolam and lorazepam are both water soluble...

If you have pure alprazolam, you can make some blotter paper with it, as it is potent enough to do this...
 
^ Erm, Lorazepam is one of the least water soluble benzos. I think you're thinking of Lormetazepam.

OP: While you don't need a P-Chem semeter to post here, I'm quite worried about you handling benzo powders (especially that you seem intent on selling them) when you don't seem to be aware of the basic fact that every benzo has a different solubility.
 
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