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basis for new types of stimulants?

^ Which research is that?

And how does that research corroborate the fact that Nicotine is the most (or second most) widely consumed drug in the world? Does said research also prove that 97.6% of humans are masochists?

As for the carcinogenic metabolite, I was under the impression that this was restricted to chewing tobacco, but I could be wrong.
 
Jamshyd said:
^ Which research is that?

And how does that research corroborate the fact that Nicotine is the most (or second most) widely consumed drug in the world? Does said research also prove that 97.6% of humans are masochists?
Click to expand...

But those folks are using tobacco... which contains beta-carbolines and thus signifigantly alters the effects.

Still, I've heard of others like yourself who use nicotine replacement systems regularly.
 
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Jamshyd said:
^ Which research is that?

And how does that research corroborate the fact that Nicotine is the most (or second most) widely consumed drug in the world? Does said research also prove that 97.6% of humans are masochists?

As for the carcinogenic metabolite, I was under the impression that this was restricted to chewing tobacco, but I could be wrong.
Click to expand...

You can use pubmed to find it quite easily. What you will have a very hard time finding is research finding mood lifting effects.

Nicotine tolerance develops rapidly and it doesn't take long before you're not experiencing the psychoactive effects.

Nicotine is well known to effect learning though. I suspect that it's effect on learning is somehow related to it's especially addicting nature.
 
^ That still doesn't explain how I and several others have been successfully using patches (eventually a stable dose is reached) for all the good effects (In my case, I've been using on and off for at least 4 years). YES it is addictive, but not nearly as much as tobacco. It isn't too difficult to simply stop using the patches and enduring a small, most mental, withdrawal.

I don't see the need for pubmed to have research on mood-lifting effects. Ask anyone who uses tobacco (or patches, or gum) why they use it, and I'm very sure "because it makes me feel like shit" will NOT be the answer ;).

Do a search on BL and you'll find several people who use it for the positive effects. There was a recent thread in HL on this issue.

Though don't worry, I perfectly understand the need to pull out all kinds of demonizing research when you're trying to quit something... hehe.
 
Long term nicotine use has positive effects from acetylcholine release. This is why you may feel some mood improvement which is caused from the decrease in anxiety, and even extremely mild euphoria that can come from acetylcholine. I would question the benefit to risk ratio of consuming nicotine in any form. Nicotine, no matter how it is consumed is a carcinogen, its metabolites inhibit genes which destroy mutated cells, so nicotine in any form significantly increases the risk of cancer. Chewing and smoking both cause damage to the cells around them which causes more cell growth to replace them thus a higher probability of mutation and thus a higher rate of cancer, there will always be cell damage however, and thus nicotine is universally carcinogenic
 
Jamshyd said:
Though don't worry, I perfectly understand the need to pull out all kinds of demonizing research when you're trying to quit something... hehe.
Click to expand...

Not trying to quit. I just don't have time right now. I would love to smoke more than I do.
 
all this bashing of cigs.
i smoke, but you think cigs is teh worst ROA?
ever tried dip?
that shit gives you an obscenely ridiculous buzz the first few times, but its fucking disgusting/horribly carcinogenic.
nasal snuff, if i could try super high potency nasal snuff i think id liek it
the snuff ive done hasn't felt strong with regards to nicotine content.
nto as strong as reds, is what i mean.
 
"Dip" may be disgusting, but it's hardly horribly carcinogenic, at least depending on the exact type. Snus, an increasingly common form is significantly less carcinogenic than cigarettes. Those new tablet things... I forget what they're called... the spitless things... they're also much less carcinogenic (at least if the concentration of known carcinogens, TSNA's, polycyclic aromatic hydrocarbons, etc, is anything to go by)
 
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