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Baclofen solubility

The_Masochrist

Bluelighter
Joined
Dec 18, 2002
Messages
206
Location
sydney
I currently take baclofen to cure my addiction to alcohol along with therapy which has been successful, i no longer drink. I am following the protocol created by Dr Ameisen which utilizes high doses of baclofen, up to 3mg per kg of body weight and even possibly higher but not exceeding 5mg per kg.

I have had troubles in my country obtaining the medication so I bought balcofen in bulk which i can confirm is legitimate. The problem i have is trying to accurately dose the medication. I would preferably like to create a Baclofen liquid solution so that i can dose the medication by volume of liquid. The problem I am facing is that Baclofen does not appear to be soluble in water or ethanol.

Is there a way create a liquid solution of baclofen with my baclofen powder that can ensure accurate dosing?

Help would be much appreciated, Baclofen has been the only thing that has helped me stop drinking and this several years supply in front of me ensures that I won't die due to alcoholism.
 
Solubility: Soluble in water (pH 7.6) (4.3 mg/ml), dilute aqueous acid (> 20 mg/ml), dilute aqueous base (>20 mg/ml), ethanol (0.02 mg/ml), and methanol (slightly soluble). Insoluble in acetone, chloroform, and ether.

A google search would have answered this. Add a little baking soda or vinegar and then phenibut will dissolve much nicer.

Even then with "typical" doses of baclofen running into the multiple grams, the best option is O or OO gel caps.
 
A google search would have answered this. Add a little baking soda or vinegar and then phenibut will dissolve much nicer.

Even then with "typical" doses of baclofen running into the multiple grams, the best option is O or OO gel caps.

Thanks, so based on what you have said, i should be able to create a solution of say 4 parts water 1 part vinegar and i would have a solution where the baclofen would be soluble?
 
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