I think the obvious answer to this topic is that of course some are and some aren't. I've seen many cases where people, myself included, talk about how a trip has changed their life dramatically, but then a few weeks later they act the same - nothing has changed at all, it was just a temporary change that elicited nothing in the long term.
In other cases the profundity of a trip's power in changing a life can sometimes be grossly underestimated.
My first experience with aMT was one of the most awe-inspiring experiences of my life and completely defeated years of my social anxiety that I'd tried seemingly everything to beat with no avail, my psychological ailment progressing and becoming worse and worse from day to day. After that trip I got out and made friends and completely turned my life around, and have had probably the best year of my life. Tomorrow marks exactly a year since that trip, and I still thank the universe for letting something so healing happen.
It's eerie looking back. Even just an hour before the trip, and even in my wildest of dreams I could not have imagined that I would have ever have overcome this obstacle that seemed gargantuan to me and impossible to get past.. but all it took was 50 milligrams of freebase aMT and 16 hours in my best friend's living room and the mountain became a molehill.