Apronalide?

[Jamshyd]

Does anyone know anything about this? The wiki page posts its pic and claims it is a sedative/hypnotic. Yet I cannot find any info on its mechanism of action.

It is available in Japan in a number of OTC analgesics as "allylisopropylacetylurea".

Worth mentioning that I took it unknowingly last week. A friend gave me an Ibuprofen pill for a headache, and I found myself unusually relaxed after taking it. After much research, I found that that pill contained Ibuprofen + the above + caffeine.

 

[jasoncrest]

Don't know if this helps you:
http://www.psychotropics.dk/usr_vie...e=All&backurlname=Search+Result&Catalogtype=A

and

http://www.chemindustry.com/chemicals/796113.html

.....not much info available...

 

[fastandbulbous]

From it's structure, I'd say it's most probably like a open ring barbiturate

 

[Riemann Zeta]

Looks kind of like meprobamate or carisoprodol. Both are non-barb, non-benzo GABA-A receptor potentiators, but with many of the same effects as the benzos.

 

[dbailey11]

They need to get that into U.S. otc headache meds.

 

[Beenhead]

that website jason crest had says it was most likely pulled from the market in most countries, why? health reasons, or recreational potential.

 

[Jamshyd]

Thanks for all the info people!

I was wondering about that as well, beens. I have a hard time believing it is significantly toxic in medicinal doses, since it is sold in Japan's equivalent to Advil and basically everyone takes it on a daily basis. The girl who gave me the pill was taking it for menstrual cramps and said it worked much better than the stuff she used in Canada (plain ibuprophen). She did not know it contained this stuff.

I am also impressed that I felt significant effects from a single pill (I don't remember the dose, but I'll be getting some more today so I'll let you know) with my general tolerance to GABAergics. Mostly muscle relaxation, on par with a large dose of methocarbamol. I wouldn't be surprised it its action is similar to carbamates.

 

[Beenhead]

Sounds like a variation of those Butabital Aspirin Caffeine talets. Rx only in USA.

They're called BAC Tablets in my Pharmacy.

 

[Jamshyd]

Well, I just took two pills about an hour ago totalling 300mg ibuprophen, 120mg Allylisopropyl-acetylurea, and 160mg caffeine. The box tells me to take "two tablets at one time, not exceeding, however." (hmm....)

I am *impressed* that this is OTC! Yes, it is very mild, but it is better than anything OTC in Canada (bar codeine, of course ). I'd say its on par with a mild benzo... although it is more physically relaxing than metnally. Too bad I never tried carisoprodol to compare.

 

[Beenhead]

Soma feels like a mix between alcohol and a benzo, with a drop of chatty-kathyness
It lasts, however, only like a half hour

Have you tried Flexeril? Cyclobenzaprine

 

[Jamshyd]

You make it sound like methaqualone

Nope, I have not tried that one either. I only had two muscle relaxants, the first is methocarbamol, and the other (also OTC) I forgot what it was called... it works on glycine receptors in the spinal chord though, i think.