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apparent 25i nBOME overdose death in North Dakota

If he used it like psilocin he very well could have ingested -- even after cooking, it's rather stable -- upwards of 50 mg of the stuff. That's well outside (100x normal dose) the therapeutic range of most drugs, and LSD and cannabis at that level are themselves not a good idea.
 
Freeotrope said:
Do you know where this information comes from? I did some searching but couldn't find anything.
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I'm having problems with it as well, and I wish I could copy something from literature before quoting a person who read something that has been overturned in more recent science. But I was told by an acquaintance of mine who is a bit like a librarian and I really expressed my doubt on the subject myself. If the theory still holds or not, I cannot say, but he had sourced it indeed.
He also had a german chemistry book from around 1900-1910, the entry for mescaline in that was hilarious. It was something like: poisoning is typified by assaulting intense colors or something like that. And a bunch of other things. Formulated like poisoning, but it was evident they were unable to make it sound less than beautiful.

Here is something though!

More than 1,5 grams of mescaline can cause liver-dysfunction and eventually death due to paralyzed bronchial tube.
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source

I'd rather have a scientific article as source, otherwise it's admittedly shitty - but still.
Makes you reconsider loading up on mescaline and taking a drug that relies on proper liver function to remain safe (idk... dextropropoxyphene? fck now I'm just thinking out loud indeed), at least.

Yet murple claims on erowid:

Q: I have read somewhere that 1200mg of mescaline can be deadly for humans (respiratory depression, liver damage), which would be three times the amount you need to have a strong trip. Is that true?

A: Any substance can be deadly in high enough quantities, even water. That being said, mescaline is one of the safest drugs known. There have been no verified human deaths from mescaline ever, although K. Trout states that there is one unconfirmed (and unconfirmable) report of a person who died during military experiments with the drug, after receiving a 15 gram dose intravenously (or about 150-200mg/kg).

In experiments with rats, the LD50 for mescaline has been established in the range of 800-1200mg/kg orally.

Considering the human dose of mescaline is around 200-500mg orally, this means you would have to try very hard to take a fatal dose. It would be extremely unlikely to happen accidentally.
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I'd have to correct any suggestion about the threshold for serious and significant organ damage to be very low or quite near a fully psychedelic dose and without better source references now place the maximum I would care to take rather between 1000-1500 mg but something I will stick by is that thinking you can just keep on going like with LSD and it's therapeutic I would think again.
Clearly there are problems with accurate numbers and statistics on the subject (acute deaths would be hard to find indeed but contribution to organ damage is of course tricky to distill from statistics) so yeah, I still agree that calling it relatively safe is indeed quite fine...
But again: the sky is not the limit.
 
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If this was legal, like alcohol, there would absolutely not be as many deaths.

It would not be available in 100mg bags of pure powder, but sold on blotters in registered stores at known doses. Add to this the fact that there would be social education about the dosage and risks, as well as possible school education and you're probably fine. A 10x overdose of alcohol will kill you easily, whereas most psychedelics have at least that margin, if not more.
 
I'd like to note that it seems the vendor I received my sample of 25i-NBOME from has stopped listing 25i-NBOMe on their site.
Hopefully this isn't price or vendor discussion.
I found it rather interesting.
Looks like you may not be able to buy 25i-NBOMe HCL powder anymore.
 
Please, don't be ridiculous, one vendor removing 25i from his stock is not indicative that all vendors will... 25i is a cash cow and it will be sold until it's banned.
 
What a shame. This happened in my state not too far from me. Someone asked me a week or two ago if I had heard of this "mushroom powder " goin around lately. I told em I'm 99% sure it has to be some synthetic and if they don't know the proper name or won't give any more info leave it alone.

...and what a ridiculous article. Confuse the kids more why don't you.

Still curious as to what happened exactly tho... chocolate, oral ingestion, etc. Wonder if anyone will ever know how much was taken and how, if other drugs were involved, if it was even 25i-NBOMe.
Just seems it would be much easier to pass off as LSD if trying to sell it as something more well known. Not that that would be any better, just sayin.
 
I hate stories like this :( A few things i am curious about... they ate it & NBOMe's have poor to no oral bioavailability, wtf? How could the "Forensic scientist" not have spent the 3min on wikipedia to know that 2c-i & 25I-NBOMe are different things? Why is the unscrupulous dealer that passed the 25I off as "mushroom extract" not being charged instead of the apparently rather ignorant guy that bought it?
 
Solipsis said:
What happened can be expected to happen again, there is an elevated chance if NBOMe compounds and Bromo-Dragonfly and DOB, etc all easily available - or even hardly available. It's a long way from escaping from the labs now, and if serendepitously ultrapotent compounds find their way into the hands of unfortunate risk-groups (ignorant people, who may not even know the identity of the compound and if they do, not know how to handle them other than eating them, snorting them or smoking them trial and error style (Yes I have heard of the latter as well in PD)).... well then it's an accident waiting to happen.
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I'm pretty sure trial and error is human nature, how else would we know what is and isn't food? But I understand your point, it's pretty stupid and sad, I agree also that education and even harm reduction is better than flat out lying and saying drugs are bad then turning around and prescribing them. I'm pretty sure it's a liability issue though, nobody wants to get sued when someone dies from ingesting a substance, and nobody wants to feel the wrath of the parents for saying it's ok to get high.
 
Agreed. It's just something nobody wants to hear, especially not in a sensitive situation where somebody has died. But there is no magical solution to this. It's part of the fact that both ignorant and vulnerable people and dangerous, potentially lethal things co-exist in this world. Not only potent drugs but also handguns and farming equipment and many many other things.
There will be kids playing around with these things, well with handguns and farming equipment you can make aware adults responsible for keeping them locked away but if something is as new as NBOMe's there is no regulation. Illegalization is the illusion of regulation because there will still be unregulated presence underground even if you turn a blind eye. Prohibiting random parties to sell this but allowing only sources that are obligated to inform and warn buyers well could help. But even then you could not ban accidents from the world because even if a buyer is responsible, things can get lost and turn up in the hands of ignorant and vulnerable people. The same is true for handguns and scythes and bug poison and so on...
 
what a shame, and crucify me for saying it but, matter of time.

you almost have to wonder how often something like this happens and doesn't receive local coverage. with all these new, ultra-potent research chems on the market, and how often the material is being mislabled and certainly mishandled, unnecessary deaths like this are going to become more commonplace. where are the fingers pointed this time? who will take the blame? because the victim isn't going to. perhaps it's time for NBOMe to be added to the D.A.R.E. program.

the whole thing is a mess but it's nor the first or last time we will see it happen - how many more times before an emergency scheduling?
 
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