anyone know the % increase of getting diabetes while on antipsychotics?

[Anon54]

so does anyone know?
& it would also be good to know the varying increases with each of the APs.

im mostly interested in the increased chance while taking zyprexa or seroquel.
im sure there are other ppl who take APs who are interested in this too. Ive tried doing research on google but although there is plenty of info i cant get the answer to my simple question. the sites that come up are often really complicated & i dont understand the. If someone could help me understand any of them it would be much appreciated.

 

[effie]

Anon, I linked you to some studies in your last thread..

I'll do another literature search later if I have time.

 

[Anon54]

^^that would be much appreciated effie.
im im going to be taking an AP maybe even for the rest of my life i dont wanna get diabetes.
im probably going to be taking either seroquel or zyprexa. so id like the statistics for both & i'll choose the one that causes it the least.
if the probably is high for both of them i might have to try mirtazepine or something but ive had it before & it gave me lucid weird dreams. Maybe just a small dose of seroquel. like 50mg 100mg max. not 200mg.

any help from anyone would be appreciated. Last thing i need on top of my anxiety/depression is diabetes. Ive been taking APs for over a year. my stupid dr forgot to inform me of any dangers. He was more concerned about no longer giving me benzos. but id rather an addiction which u can just taper off than diabetes.
I was once addicted to valium & it was easy to quit cuz i stuck to the taper plan.

..now i have to buy valium & temaz.... oh well. another story

 

[eukaryote]

I'm having a difficult time finding any study comparing Olazapine or Quetiapine new onset diabetes and hyperglycemia over that of non-treated psychiatric patients that is of good quality. Quickly looking, it seems to be 20-35% over patients treated with haloperidol, with a higher incidence in males over females, in persons under 50 vs persons over 50, over a time of 1 year.

As an aggregate, persons with schizophrenia or bipolar have a 2 to 3 times higher incidence of diabetes then the general population. I mention this as the vast majority of the studies on this issue are in populations with these disorders.

However, that is not a definitive answer, that is me trying to give you a simple answer from very complex data. There is a reason the data is complex, because its a complex question, complex to study, and complex to answer.

There is disagreement on the exact prevalence of diabetes related adverse events with regards to anti-psychotics period and with regards to individual agents, between different authors.

A large factor in the development of diabetes due to anti-psychotics is the associated weight gain. With a dose of 50mg of quetiapine, this unlikely to be relevant. As always you an reduce the risk by maintaining a healthy body weight, regular exercise and a diet that avoids large quantities of simple sugars and fats, particularly animal fats.

In any event, the absolute risk of new onset diabetes in a person between 18 and 55 is quite small. Never the less, if you are started on a atypical anti-psychotic, it may be prudent to have regular testing done with your physician to monitor for metabolic changes, as well as a test prior to commencing treatment.