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Any way to counteract Paxil when rolling?

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velocity92c

Bluelighter
Joined
Jun 29, 2009
Messages
82
Rolled last night for the first time in two years with a girl I've been dating for 3 months now. Last night was her first time, and supposedly the best pills that have been around these parts in years. Anyway, I was lit up about 20 minutes into it off of 2 pills, which is the least amount of pills I've taken in at least 6-7 years. Bottom line : they were good. Some of the best I've ever had. My girl, however, never felt a thing. Nothing at all. I had read online about SSRI's and E not playing nice together but beforehand it never even entered my mind. All night long I kept wondering why she wasn't feeling anything, then when I finally came down I realized it must have been her Paxil.


tl;dr Is there any way to counteract the blocking effect of Paxil without stopping the medication? She gets horrible withdrawals without it and has been taking it so long it would likely take months for the blocking effect to fade anyway. Or any other advice at all? I'd really like her to experience rolling while good pills are around, they don't come around here often anymore.
 
If you're so chronically depressed that you need Paxil, then MDMA is not a good drug for you anyways. It's sort of a good thing that SSRI's prevent MDMA from working.
 
Damn.. I think I'd rather roll once in awhile than be paxil-ated.. (I currently take paxil, and I don't know if the fake-ish energy and near constant sexual disfunction is better than a 3-4 hour true look at life and complete drop of defenses and gaining in ability to bond with people every month or two is worth it... 0.o
 
AfterGlow said:
If you're so chronically depressed that you need Paxil, then MDMA is not a good drug for you anyways. It's sort of a good thing that SSRI's prevent MDMA from working.
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It often surprises me how many people want to come off their meds (usually for depression) to take something whos side effects = depression?

Stupid IMHO
 
AfterGlow said:
If you're so chronically depressed that you need Paxil, then MDMA is not a good drug for you anyways. It's sort of a good thing that SSRI's prevent MDMA from working.
Click to expand...


Agreed, and I'm several anti-depressants. It's not worth it to get off and possibly get really depressed (I tried Effexor instead of Cymbata like a year ago and got suicidal, but I have really bad depression).. got back on Cymbalta, which works for me apparently (I wasn't sure cause I've been on it for 4 years). Bottom line is if it's working for her depression and she's been on it for a long time, it's not a good idea to screw with it. One day if she gets off, rolls will still be here.
 
velocity92c said:
I had read online about SSRI's and E not playing nice together but beforehand it never even entered my mind. All night long I kept wondering why she wasn't feeling anything, then when I finally came down I realized it must have been her Paxil.
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SSRI's counteract MDMA
after all the paxil enables the serotonin to be absorbed faster by surrounding axons
MDMA releases all serotonin complete opposite of what the paxil does
plus shes risks getting serotonin syndrome if shes combining the two
tell her to stay off the paxil for a good 3 days before you plan on rolling
 
Ive given out many many caps of molly powder and this is easily the most common problem people run into. Every now and then someone coming back like "that stuff was totally bunk I didnt feel shit and youre paying me back or dosing me again right now". I always ask them if theyre on ssri and with ONE exeption they have always said yes. Its really hard to communicate this point that if you are on any kind of moderate to heavy dose of ssri you WILL NOT ROLL. period. Youre only option is to quit your meds which is straight up stupidity. And on top of that its dangerous to combine cause you can get serotonin syndrome and be an` emotional retard forever.
 
lasthurrah19 said:
Agreed, and I'm several anti-depressants. It's not worth it to get off and possibly get really depressed (I tried Effexor instead of Cymbata like a year ago and got suicidal, but I have really bad depression).. got back on Cymbalta, which works for me apparently (I wasn't sure cause I've been on it for 4 years). Bottom line is if it's working for her depression and she's been on it for a long time, it's not a good idea to screw with it. One day if she gets off, rolls will still be here.
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Glad you found something that works. I was on effexor and it never worked, then I started smoking weed regularly in HS and my depression cleared up and I stopped taking the SSRI's. I wish I could find something legal to clear my depression.
 
severely etarded said:
Glad you found something that works. I was on effexor and it never worked, then I started smoking weed regularly in HS and my depression cleared up and I stopped taking the SSRI's. I wish I could find something legal to clear my depression.
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Well, when I say it works for me, I mean it keeps me from being suicidal 90% of the time. Which is a great thing, but I am still depressed as fuck... but no other anti-depressant has worked for me at all. I should also mention that it's not the only thing I take - I also take Wellbutrin, Remeron, Seroquel, Lamictal, and Neurontin (weaning off of it right now, it never helped me)... I've been getting a bit less depressed lately, but that just means I'm leaving the house a couple times a week as opposed to only for therapy and meds (I also do therapy with my psychiatrist). So yeah, my perception is a little screwed up here, now that I think about it.

I'm glad weed works for you, it does for me if I smoke it regularly, but I can't afford it and also it can lead to other drugs (for me, I was addicted to oxy for about 1 1/2 years in 2007-2008). I do think the medication I'm on helps me, for sure as I see how bad I get when I try other things. I personally think I'm at or close to the best effect I can get from psychiatric medications, with this huge combo. Took more than a year to get here, but I have a great psychiatrist that I trust. Obviously I had reservations about being on so many medications, especially Seroquel, but I was seriously not going to make it at the time I got put on it in early 2010. Also, I'm not a zombie on this combo, emotion wise I feel things more than I used to, cause I have a dissociative disorder that was out of control before I started therapy and medication. I dissociate about 50% less I'd say than I did before meds and therapy - although therapy has a lot to do with that. Anyway, I'm rambling.

There's more SSRIS/SNRIs/Tricylics out there, if you're patient and don't mind going through possible side effects/failures of medication... well, it's helped me, that's for sure. But it's probably easier and better for your body (just my opinion) to stick with weed.
 
I just got put on lexapro and vivanse. I'm taking a break from rolls and weed for a while i started to feel too funky thought i was losing my mind.
 
ecstasyboy717 said:
I just got put on lexapro and vivanse. I'm taking a break from rolls and weed for a while i started to feel too funky thought i was losing my mind.
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Good job putting your health first, and good luck. Lexapro was the first anti-depressant I got put on, and my mom is on it and it works for her.
 
Yeah i'd rather have my mind then do drugs all the time and have no concern about my health. I also have xanax for anxiety. Did lexapro work for you?
 
ecstasyboy717 said:
Yeah i'd rather have my mind then do drugs all the time and have no concern about my health. I also have xanax for anxiety. Did lexapro work for you?
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It did kind of, for about 3 months at 30mg I think. What happened was, I was blocking out all of the crap causing me PTSD and I did acid and it came to me then and freaked me the fuck out and I needed to get an AD and some benzos. I went there like a week later and got the Lexapro, 0.25mg klonopin wafers (she told me to take two if one didn't work, which I did, and I got 0.5s from then on). It was 30 of them for one month, PRN as needed for panic attacks. At this point I was waking up with a panic attack every day. Lexapro stopped that, didn't do much else but I was able to function at that point in time. When I told her that I was still depressed but having less panic attacks, she switched me to Cymbalta. I was on 120mg, the max dosage. Most of my suicidal ideation when away at this point, I was still blocking out a lot of things and she didn't know about anything, I never told her because I was suppressing it/in denial for those years.

Eventually I did tell but I've already gone way off topic. Early in 2010, after about 4 years on Cymbalta and also being on like three other meds in my cocktail (no narcotics), an inpatient doctor tried me on Effexor but I suddenly got very suicidal once all the Cymbalta was tapered, and she switched me right back. She also put me on Abilify and it gave me terrible anxiety, after three days she took me off it. I get periods I guess where my PTSD goes into overdrive and I self harm or start planning suicide and looking up what of the meds I have will kill me if I OD on them and things like that.

I tried paxil, prozac and zoloft when I was much younger, like 13/14 and they all made me anxious and prozac made me somewhat verbally aggressive and then I moved away at 15 to get the fuck away from my parents and I went with this guy, let's just say it was a bad decision. So that was the end of treatment for me at that point.

Sorry for my life story

tl;dr - Lexapro helped a little, Cymbalta seems to work the best, side effects were too severe from the others I took.
 
Wow you have been through a lot. Well my doctor prescribed me a shit load of every class of drug. Lexapro,Vivanse,Xanax,Seroquel. Some weird shit happened last night when i took seroquel for the first time my vision went black then i got really confused and all of a sudden the walls started coming at me and shit i was freaking balls.
 
Not everyone takes SSRIs for depression. Cymbalta, for example, is prescribed for ADHD.

Of course it still inhibits mdma, but the consequence is not necessarily amplified depression.
 
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