Any classic phenethylamines from the S-isomer?

[boinghd]

Hello,

Someone I know is presently in possession of a large quantity of phenethylamine nutritional supplement. He is wondering if it'd be possible to synthesize any psychotropic (preferably more active than S-phenethylamine)
substances therefrom.

I've informed him that it would be less-than-prudent to do so, so he won't try it anyway. But as he has an interest in organic chemistry, he'd really like to know if any easy (or fairly direct) syntheses are possible with readily-available
reagents.

If you could, he graciously requests that someone would fortify his mind a bit.

Thanks

PS. apologies for this question out of the blue.

 

[plusfourpirate]

someone correct me if im wrong, but no synth discussion here on bluelight if im not mistaken. *but, to answer your question simply= its just not that easy bro.

sorry mang; there are places out there that could give you better answers; you just have to look around a little..

buena suerte

 

[sn23]

Without going into synth discussion: theres no way to produce R- or S-compounds starting from phenethylamine without chiral reagents because plain phenethylamine is not chiral. One always ends up with racemic product. Nothing more to say.

 

[greenmeanies]

Study chemistry moar. Look in PIHKAL and find that there are zero reactions that start with phenethylamine itself. It is near impossible to start with the skeleton and attach things to specific points of the ring. You must start with the correct "phenyl" ring, and then attach the rest of the "ethylamine" skeleton as the last step. Can be seen in nearly every PIHKAL synth (except for the few workarounds like psi-2C-T-4). There is no way you could perform any of the recipes from this book because you simply do not have the theoretical background. By all means go to school for organic chemistry and prove me wrong.

Leave the kitchen chemistry for the meth lab.

 

[Solipsis]

1. no synth discussion, at least not 'how can I easily make ... ', only harmless talk about things widely known.
2. it's already been said: it's not as simple as what you suggest. Yes it has the backbone or IS the backbone skeleton for a whole family of compounds but to make something you need to have something like a 'growing stub', to keep it nice and vague in explaining this. You can't just stick anything to the structure, you have to make bonds, like building bridges - the bridges need to be built in certain ways. Phenethylamine itself is mostly a dead end. You can turn it into other things but nothing useful I think.
3. no no