Specified
Ex-Bluelighter
What drugs will work while being treated with antipsychotics?
Because paliperidone is a 5ht-2a blocker (not sure if reverse agonist or antagonist) LSD, psilocybin, mescaline, and DMT are out. Since paliperidone is an antipsychotic I'd really stay clear of most everything until I didn't need paliperidone anymore. Even cannabis is problematic as it increases dopamine in places. I don't know of a safe combo with paliperidone. Benzos probably wouldn't have bad implications with worsening psychosis but you'd have the additive sedation thing going on. CNS stimulants are definately a problem for potentially worsening psychosis.