Misc Anti-fungal Medication with Percocet: Safe?

[Michael_25]

I was recently prescribed an anti-fungal medication. This stuff is pretty heavy on the liver, so much so that after 4-weeks on the treatment I need to have liver-function tests performed. It strictly says on the packet not to drink alcohol on the medication. That's fine, since I rarely drink. However, I do indulge in Percocet a few times a week.

I just wanted to know if taking about 2 grams of APAP in one sitting 4 or 5 times a week will overload my liver while on this anti-fungal medication. The anti-fungal drug's name is "griseofulvin (500 mg)." I've searched the Net for info but there is none.

Btw, I do perform CWEs (only if it's a low oxycodone, high APAP formulation of Percocet); the 2 grams of tylenol probably doesn't seep through into the mixture. But it may have at times, hence the question.

Thanks for your help, guys.

 

[CrimpJiggler]

Yeah I strongly advise avoiding taking any APAP while taking the antifungal. If they're making you go in for a liver function test, that drug must wreak havoc on the liver. Definitely do the CWE to get rid of as much acetaminophen as possible. I don't know anything about oxycodone, if CWEs cause you to lose a lot of oxycodone, I'm sure there are other solvents you can use to get rid of the APAP. I know for a fact that acetaminophen is extremely soluble in methanol. Its fairly soluble in acetone too. Heres a solubility list:
http://old.oru.edu/cccda/sl/solubility/allsolvents.php?solute=acetaminophen

Is it a serious fungal infection? I'm guessing its an internal one. Although its very controversial and I'll probably get heavily flamed now for bringing it up but I've tried colloidal silver for myself and it seems to work. I've tested the stuff on food and I know that it definitely kills fungi. It kills mushrooms and mold, so it would definitely kill the unicellular types of fungi which infect multicellular organisms. The controversy revolves around its use in vivo. The only side effect caused by colloidal silver seems to be argyreia which is a buildup of silver particles under the skin than literally turns you blue like a smurf. Thats obviously an accumulative effect though so it doesn't apply to ingesting once to kill an infection.