Anti-depressants

opioids are the best antidepressant imho

:p

If that was the case i would not have to take bupropion, lamotrigine and seroquel all to help my bipolar disorder. Opioid's don't do much at all for really bad depression atleast not for me. Also telling anyone to take opioid's for depression is a awful idea since it is just asking for addiction. Their tolerance will skyrocket for starters as the psychological effects of opioid's go away before the painkilling effects so the person would have to keep upping the dose. Also when the person runs out they will experience a WD induced depression that makes your worst nightmare look good :\

Maybe if the person was on a very short leash and had not responded to any other treatment then opioids would be a option. I think some opioid's such as buperenorphine are more helpful in this regard then say morphine or hydromorphone. Tramadol is one that is used off label occasionally for depression as it is a SNRI along with being a very weak mu agonist. But tramadol has hellish wd effects exactly because of those properties. Think of withdrawing from effexor and a opioid at the same time and that's what tramadol withdrawal sounds like from what people have told me 8(
 
it is common knowledge opiates cause or make depression worse in long term...

I heard Lexapro+ Wellbutrin together will bring people out of the pits of hell
 
I've been through 6 ADs to find one I could tolerate, reports fro others on the same substances have shown me that people react totally differently to the same drug.

What is important, of you want to use ADs is to be prepared to tolerate the first week or so which will often bring nausea and you may feel generally not great but also not to tolerate excessive side effects. IME doctors can expect you to put up with too much in some cases, of your really feeling ill on something or its having a seriously disturbing effect on you then go back to the doctor and explain that you are not happy with that particular drug.

Some people suffer little in the way of side effects, for me I can't seem to tolerate SSRI's at all with symptoms from hallucination to vomiting and more, mirtazepine brought on severe derealisation, which I can suffer from anyway but this was constant and I had to soe off it pretty quick, it just felt like I was coming up on acid the whole time, where as others find it works well for them

I'm currently taking Venlafaxine (Effexor) and seem to tolerate it quite well, with the nausea decreasing in the first couple of weeks. I do get some side effects from it, decreased appetite, occasional disturbing dreams, lack of interest in sex although I'm still functional and with a bit of encouragement still maintain intimacy with my partner and my sleep is not great although to be fair this may be related to my benzo use.

Without ADs I start to have suicidal thoughts, I'm having CBT and I do hope that in the suture I can stop taking them but for now I feel I need them to stabalise me so I can function well enough to work o sorting things out in the longer term. I would always recommend counseling of some kind, my CBT has moved me forward taking pills won't do that.
 
And good luck finding someone that will give you low doses of Ketamine, it's illegal and a scheduled drug, not to mention it's only available at Veterinaries.

Ketamine is an anesthetic which is used both in animals and humans. I've never heard of someone getting a prescription for it, but it's still commonly used in hospital settings, especially for anesthesia in children and in people who come into the ER who may have an unknown amount of other drugs on board, as well as on the battlefield, etc. It doesn't depress your respiratory function as much as many other anesthetics, so it's less dangerous to use in those situations.

I know of one doctor who uses Ketamine exclusively as an anesthetic when he performs electroconvulsive therapy for depression, and of another doctor who has administered a low dose of IV Ketamine to at least one of his depressed patients (it didn't work for that patient). It's an off-label use, but left up to the discretion of the doctor. I'm guessing most docs wouldn't be comfortable with the liability as it isn't FDA approved for depression, and it's still in the clinical trial phases, but it can't hurt to ask.

Another option would be to enroll in a clinical trial, but there's no guarantee that you'll be on the Ketamine arm of the study and you might be getting a placebo.

Ketamine clinical trials link
 
TL;DR I fit the diagnosis for Schizoid Personality Disorder, but I find some of the symptoms to be (fucking silly) relative to life as opposed to an inherent personality.
I'm seeing my psychiatrist for the second time in a little over a week. At the end of my first session, he said he thought I have Schizoid personality disorder. Now, although I do have at least the minimum amount of symptoms in both the DSM and the ICD, I have a fucking problem with this. The thing is, so many of these symptoms are relative to ones lifestyle and not some inherent personality.
They both say something along the lines of "Lack of desire for sexual experiences with another person" which is true, although it's dependant on my life. I'm sure if I didn't have the internet/100gb of porn I'd have more of a desire for sex, or maybe if I had a girlfriend. I don't know about the second one, though. I mean, I've had sex before, and fuck is it over-rated. I'm that lazy I'd rather fap when I can have sex, although I love eating chicks out and fondling breasts.
They both say "Taking pleasure in few, if any, activities" which is true.
They both say "Indifference to either praise or criticism" which I'm unsure about. It really depends on the person, it's not like I'm indifferent to praise or criticism, it's more so the people giving praise or criticism I regard lowly, almost with disdain.
They both say "Emotional coldness, detachment or reduced affect" which is true.
They both say "Consistent preference for solitary activities" which is true, but once again relative to life. If I had someone in my life I wanted to spend my time with (which has happened before) I would, but I'm alone. I lack meaningful bonds, and once I'm home, I can't see the point in leaving the house to see people unless it's for drugs.
That's all the symptoms they both share, and I have 4 of these symptoms, which is the minimum required for a diagnosis.
The DSM says "Lacks close friends or confidants other than first-degree relatives" which is true for me, although it hasn't always been the case.
The ICD on the other hand says "Very few, if any, close friends or relationships, and a lack of desire for such." which is untrue, as I do have a desire for such.
The last DSM symptom is "Neither desires nor enjoys relationships or human interaction, including being part of a family" which is untrue
This leaves me with a total score of 5/7 for the DSM
There are 3 more symptoms for the ICD such as "Preoccupation with fantasy and introspection" which is untrue.
The last 2 I have trouble with. The first one being "Limited capacity to express either positive or negative emotions towards others" which I cannot understand. Limited capacity? What the fuck is normal capacity? You can express an emotion you don't have, what you can't do is feel an emotion you don't feel. I don't want to get off-topic though, I've rambled plenty so far and I'm continuing to do so and you're still reading because you're stupid. Anyway, I just don't understand. I can hit someone, I can hug someone, I can kiss someone, I can give them a thumbs up or the finger. I can smile or frown, so I'm stumped here.
The last symptom here bothers me. "Indifference to social norms and conventions" Somehow an indifference to stupidity is a negative reflection upon my personality? What kind of fucked up bullshit-
This just seems completely fucking silly to me.
Anyway, that's 5/9 for the ICD
Also, according to Theodore Millon I'm a Languid schizoid.
If we go with Harry Guntrip (http://en.wikipedia.org/wiki/Schizoid_personality_disorder#Guntrip_Criteria) then I'm an introverted, (covertly) withdrawn, self-sufficient, superior, lonely fuck with loss of affect.
If we're gonna go with Akhtar, see this pic.
I've been on Fluoxetine for about a month now, and I don't know if it's had any effect or not. I'm going to ask about Risperidone and Bupropion next appointment, as he is the one who suggested I have SPD.
Although, it has been harder for me to cum and I've had less of a sex drive the past few days/week, and I'm blaming the Fluoxetine.
 
DeathDomokun:

I started taking venlafaxine and mirtazapine 6 months ago. I was battling with depression and anxiety since 16 (i'm 28 ). I feel great; felt great after the first day.

I've gained 16 kg, which is a lot, but since I was always ultra skinny (53 kg) that's not a problem for me.
 
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I had my last appointment last Wednesday. I haven't taken any Fluoxetine since that day.
The psych was pretty adamant that I didn't have a depressive disorder. He said since the Fluoxetine didn't improve, and may have worsened my memory/cognitive function and concentration. It also didn't improve my energy and I was actually more worn out by the end of the day. Because of this, he is adamant that it's not something that can be fixed with medication so I didn't ask to add Bupropion/Wellbutrin to the mix.
He thinks my problem is with my personality, still of the opinion I have Schizoid Personality Disorder. He said he didn't think a psychologist/therapist was essential as I'm aware of what society expects of me/my needs/a smart enough guy...
I don't know. I am able to continue, I know I can get through this. I just don't want to. I don't see the point in life. My head is void of joy, contentment, purpose, and will.
I'm clinging onto whatever meaning I have and I'm stuck in this limbo between nonchalance and dissonant care and I'm apathetic to such an extent that theres-
I just don't know.
 
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Oh, one thing the Fluoxetine did do though was make cumming feel better. It seemed to have improved (there's a name for it, it's when orgasming/cumming doesn't feel good) that, but it also lowered my libido and made it harder/take longer to cum.
Sorry for double post.
 
Hey just read through your posts Deathdomokun and share a similar (motivational) depression....i had been on and off most of the SSRI's for years without much satisfaction/improve to my quality of life.... i use to get so incredibly fatigued on them, which made my depression worse... However this year after spending a bit of time reading up on antidepressants i stumbled across some information on Reboxetine. Anyway, i decided to go to the dr and get a script and it has been the best medication i have ever taken. For the first time ever, I feel somewhat normal and dont face each day as a challenge with the day-day activities/tasks being tedious. It has enabled me to function and feel good. It has worked miracles for me and i think its well worth a try. Furthermore, i can orgasm easily!! There has been absolutely no negative impact on my sex drive, woohoo! :-) I love Reboxetine, it has changed my life. I found it didnt take long to kick in either.
 
it is common knowledge opiates cause or make depression worse in long term...

I heard Lexapro+ Wellbutrin together will bring people out of the pits of hell

As did I. Then I tried it once for four months - no effect. Tried it a year later for 8 months - no effect.
Every one of the anti-depressants and combinations on the dizzying litany of those I've tried - no effect.
And when I say no effect - thats literally what I mean; no withdrawals, no adverse reactions.
 
It's good to hear that you're finally getting somewhere with Roboxetine Bouncey.
My psych was pretty adamant that no medication would help after Fluoxetine not helping, and I don't want to try to persuade a professional to do their job differently, even if I disagree. Thanks all the same for the advice/information though.
I think I'll just go on as I always have :\
 
It's good to hear that you're finally getting somewhere with Roboxetine Bouncey.
My psych was pretty adamant that no medication would help after Fluoxetine not helping, and I don't want to try to persuade a professional to do their job differently, even if I disagree. Thanks all the same for the advice/information though.
I think I'll just go on as I always have :\

How long did it take for your psychiatrist to diagnose you with schizoid personality disorder? I would take that with a very big grain of salt because psychiatrists often seem to put personality disorders on people who are treatment resistant or are difficult to deal with. I got slapped with narcissistic personality disorder back around 2006 and it was only after i had seen my psych maybe twice. The valproate i was on was not working to stabilize my moods and neither was the seroquel or bupropion. She didn't even tell me that she diagnosed me with that and i only found out when i finally got to see a new shrink after the one that diagnosed me with narcissistic personality disorder dropped me :X . Looking back i should have sued her as taking me off all my meds and upping my gabapentin dose (oh she loved that wonderful med 8) ) made me have awful mood swings and i was very suicidal on and off until i got stabilized on lamictal nearly a year later! fucking bitch :!

My new shrink that i got after dropped the NPD diagnoses right away and i ended up being diagnosed as having bipolar NOS (i get full blown mania, mixed states, rapid cycling, etc so i could probably fit BP1) and i was treated for that. Once the lamotrigine finally started to work i felt like a person that had been through a long storm but came out the other side. I would get a second opinion if at all possible if i where you.
 
It's good to hear that you're finally getting somewhere with Roboxetine Bouncey.
My psych was pretty adamant that no medication would help after Fluoxetine not helping, and I don't want to try to persuade a professional to do their job differently, even if I disagree. Thanks all the same for the advice/information though.
I think I'll just go on as I always have :\

...what a shitty and deflating thing for a psych to say...dont let his option dissuade you and make you lose confidence in seeking medication (or whatever treatment it is you may need) in order to feel good and manage your "depression". if it's any consolation, ive tried Fluoxetine and found it ineffective, yet i have now found something that works for me. There are plenty of options and combinations out there it's just a matter of trial and error. I think most ppl go through a string of meds/treatment in order to discover the one that suits their needs best.... i hope
 
It's good to hear that you're finally getting somewhere with Roboxetine Bouncey.
My psych was pretty adamant that no medication would help after Fluoxetine not helping, and I don't want to try to persuade a professional to do their job differently, even if I disagree. Thanks all the same for the advice/information though.
I think I'll just go on as I always have :\

...what a shitty and deflating thing for a psych to say...dont let his option dissuade you and make you lose confidence in seeking medication (or whatever treatment it is you may need) in order to feel good and manage your "depression". if it's any consolation, ive tried Fluoxetine and found it ineffective, yet i have now found something that works for me. There are plenty of options and combinations out there it's just a matter of trial and error. I think most ppl go through a string of meds/treatment in order to discover the one that suits their needs best.... i hope you keep sussing out your options, it's worth it in order to feel happy... :-)
 
How long did it take for your psychiatrist to diagnose you with schizoid personality disorder? I would take that with a very big grain of salt because psychiatrists often seem to put personality disorders on people who are treatment resistant or are difficult to deal with. I got slapped with narcissistic personality disorder back around 2006 and it was only after i had seen my psych maybe twice. The valproate i was on was not working to stabilize my moods and neither was the seroquel or bupropion. She didn't even tell me that she diagnosed me with that and i only found out when i finally got to see a new shrink after the one that diagnosed me with narcissistic personality disorder dropped me :X . Looking back i should have sued her as taking me off all my meds and upping my gabapentin dose (oh she loved that wonderful med 8) ) made me have awful mood swings and i was very suicidal on and off until i got stabilized on lamictal nearly a year later! fucking bitch :!

My new shrink that i got after dropped the NPD diagnoses right away and i ended up being diagnosed as having bipolar NOS (i get full blown mania, mixed states, rapid cycling, etc so i could probably fit BP1) and i was treated for that. Once the lamotrigine finally started to work i felt like a person that had been through a long storm but came out the other side. I would get a second opinion if at all possible if i where you.

He diagnosed it very early, I think it may have been in the first session. I think it's bullshit, as the symptoms are silly and not even my problem.
Psychiatry is very off putting at the moment.
I was thinking about just asking my GP to prescribe me medication but I don't know whether she'd be willing to or not.
 
I've recently been prescribed Effexor and am noticing positive results thus far.

The first five days I took 75mg as prescribed and after day five it goes to 150mg. I'm currently on day eight.

I was surprised to notice a change on days two and three. The only side effects so far is one instance of nausea and light headedness. I'm experiencing shortness of breath but it's hard to say if it's from the cigarettes or my allergies from being around cats the past couple of days.

I'll take those side effects over how my head has been prior to the meds
 
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