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AMT, prozac and serotonin syndrome

slush puppie

Greenlighter
Joined
May 2, 2010
Messages
23
Hi, I’ve been on 20mg fluoxetine (Prozac) since May and decided before Christmas to come off it. I haven’t taken any at all since the 3rd/ 4th January, and before that I'd spent a couple of weeks on 10mg every other day. I want to take an oral dose of 30-40mg AMT for my birthday tomorrow. I know it’s only a mild MAOI and I have read stories of people missing their day’s SSRI and taking AMT with no consequences. But I know prozac has a longer half-life, so I’d like your thoughts. Do you think I would be at any real risk of serotonin syndrome? And should I be careful to avoid foods containing tryptamines, too?

Thanks :)
 
Yes, you would be taking a risk. It is up to you whether the risk outweighs the possible reward, or vice versa. I have personally taken MDMA and aMT in the same day with no ill side effects (This does not mean I recommend it).

I believe it's generally recommended to wait 4-6 weeks after stopping an SSRI to start takin' drugs like this again.

I hope you are safe brother, and have a happy birthday :-)
 
like cryptix said there's definitely a risk, but in the end it's up to you. If your prozac dose has always been at 10mg, that's fairly low i believe so it should lessen the risk a bit. Generally the very minimum recommendation for waiting to use an MAOI after an ssri or visa versa is 14 day but it'll take up to 4-6 weeks to be completely out of your system especially since you've been on it for 8 months. Wikipedia says that doses as low as 20mg can have dangerous adverse effects but I'm not a doctor or very knowledgeable about AMT. If you decide to go through with it maybe try a smaller dose first though idk if you can redose effectively with AMT. Either way happy birthday and be safe.
 
The half life of prozac is 4-6 days in chronic users so you will probably have a significant amount still in you. Given the concerns about aMT being an MAOI, I would steer clear if I were you. I understand it's your birthday, but maybe wait a while.
 
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