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AMT and appetite

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Xamkou

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Sorry if this is a stupid question but:

Why is it so easy (and quite nice, infact) to eat on AMT? It's the only stimulant that I'm able to eat on.

Thanks

<3
 
AMT is one of the very few tryptamine stimulants and it would actually be classified as a psychedelic somewhat quicker or at least an entactogen (nitpick..)

Anyway that is not much of an explanation at all, I know. One thing that I do think of AMT is that it isn't very tense, compared to other compounds with stimulant effects it is pretty drawn-out, I always use the term dilation. That dilation might just be the reason for something opposite to push. What I would call push is probably MUCH more dopaminergic in effect than serotonergic like AMT is (also a hint towards the answer to your question), I find butylone to have one of the strongest pushes I know by the way. This push is a total deal-breaker when it comes to eating.
 
I believe it is that same 'push' effect that quells appetite when one is nervous. When you're extremely nervous, the thought of food is repulsive in exactly the same way as when you're feeling the push of a drug. Methinks it's the dopamine to blame.
 
Definitely, but I would not rule out adrenaline or noradrenaline either.
 
I find AMT very speedy however, which makes me think it releases a lot of dopamine and noradrenaline, especially during the first four-six hours.

Mystery to me...
 
You appear to be correct:
αMT acts as relatively balanced releasing agent of serotonin, norepinephrine, and dopamine,[4] and as a non-selective serotonin receptor agonist.

I too am mystified.
 
I eat like a horse whilst on MDPV binges sometimes and that's way more heavy on the dopamine than aMT is. You couldn't pay me to eat on MDMA but 2Cs give me the mad munhiez. Don't think I had much appetite on aMT really but has been a while since I used it. Think it's probably down to the individual and their own body chemistry more than simply the drug, personally.
 
"Serotonin provides a feeling that satisfies hunger and may improve sleep and relaxation.

http://www.livestrong.com/article/351011-treatment-for-depression-a-balanced-diet/#ixzz1FQ1NUZxT"

" A rise in serotonin levels in the nucleus accumbens is the "off switch" for the hunger, anxiety, or longing - the need disappears.

http://www.internet-of-the-mind.com/addict.html
"
couldn't find a reliable source but theres a lot of references stating the above

it's the serotonin, in my opinion. mdai removed any desire to eat and made it pretty much impossible(same with mdma, methylone, and amt(!) for me). amphetamine isn't nearly as bad in that respect, nor is desoxypipradol, but they still hinder eating.

actually I'd say it's norepinephrine/adrenaline and/or serotonin as they both seem like they would lower (atleast my) hunger.

if I smoke weed with the amt I can eat no problem, and thats generally what I do.. but amt alone.. maybe after the peak it gets easier to eat..
 
Eating on 2c's, aMT, mpa, mxe & MDPV is succesful for me.

Not so on LSD, MDMA, Shrooms, speed, coke.

Horses for courses I guess...
 
Moved here from PD by request. Not sure who merged it into the B&D aMT thread but okay. I do agree it's a somewhat more complicated subject that I wouldn't mind seeing some brilliant ADD brains feasting on. :)
 
While it technically binds to most 5-HT sites, AMT's highest affinity is for 5-HT2a, which is actually rather high at around ~50nM (double check on that, its been a while). I do know that its affinity for 5-HT1a is around 1/40th that of 5-HT2a, around 2000nM (yes, seems odd, considering AMT has negligible visual activity, this is the reason why I roughly recall the affinities). I do not recall the affinity for 5-HT3, but I would bet the number is high, certainly well into the uM range (micromolar, my phone's voice recognition software doesn't bring up the symbol for "mu", although for some reason it recognizes "delta"). My point being, perhaps its low affinity for 5-HT3 explains why it does not have a pronounced appetite suppression........

AMT is a rather potent releaser of NE, and like amphetamine is also re-uptake inhibitory. However, AMT's potency as a releasing agent of monoamines is greater than its affinity for the transporters. I would assume neurotoxicity would be a serious issue with continued use of this drug.

But, I never liked AMT. I played a mean joke on a friend many years ago (decade), I prepared a finely chopped up line of AMT (~80mg), and told my friend it was cocaine. He snorted it, eyes started watering, face turned red. That stuff hurts. 8 hours later he evidently called up an ex-girlfriend in the middle of the night to tell her that he "still loves her" or something to that effect. All in good fun.......
 
I've had aMT twice, the first time it was extremely stimulating... Nothing short of a good amount of regular amphetamine with a little bit of true psychedelic and MDMA-touchyfeely mixed in.. VERY pleasurable to say the least.

The second time was a real bummer, it made me and also my two friends really drowsy... VERY weird.. it was the same batch so the only explanation could be oxidation or a paradoxical effect. All of us where AD(H)D if that matters.

On the food issue: Chocolate was great the first time.. I remember that. I can even eat on high dose MDMA and enjoy it so I'm not the best person to ask.
 
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