Hi,
I'm thinking about trying amineptine for treatment resistant bipolar2 depression. i am struggling with motivation, drive, libido, anhedonia. i have been through the ringer, and feel like i've been on every psych med in every combination over the past 7 years. I am currently on a combination of bupropion xl 600mg, mirapex 1.5mg, adderall, saphris, cerefolin and a bunch of supplements. i am up and out of bed and somewhat functional but life still really sucks and even with all this dopamine action going on, i feel like something is missing -- the drive and initiation and caring is so lacking, and the apathy, resignedness, hopelessness, givingup is so present.
I know i know, it's not all about neurochemistry. I'm doing the psychology stuff. My testosterone levels are low, trying to treat that as well.
But anyway THE QUESTION I HAVE IS:
Does anyone have experience with amineptine, compared to other dopaminergic agents? How does the subjetive experinece compare say between amineptine and bupropion, and compared to adderall or mirapex. Would I conceivably have to stop the stimulant if I tried amineptine?
Has anyone had good results with it? Or heard of anyone with good results?
I've tried MAOIs before, they help somewhat, but I have other problems with them.
7 years ago in college, I had so many ideas, ran a business out of my dorm room while getting three engineering degrees. Now at age 31, I fucked up the great job I had in technology, i am broke, living at home with parents and still can't find a job despite ivy league education because of my illness. So yeah, my apathy might be situational, but I'd like to think its more complex than that, and I know the amotivation killed my job performance.
Personally I think years of ephedra diet pills, then SSRI use fucked up my dopamien system pretty badly.
Also, last year I got highly addicted to PEA + MAOI...but that was the only thing that kicked the depression in the butt...at least before it caused hypomania and destruction, so I had to go off of it.
Anyway, please, any feedback would be appreciated.
I'm thinking about trying amineptine for treatment resistant bipolar2 depression. i am struggling with motivation, drive, libido, anhedonia. i have been through the ringer, and feel like i've been on every psych med in every combination over the past 7 years. I am currently on a combination of bupropion xl 600mg, mirapex 1.5mg, adderall, saphris, cerefolin and a bunch of supplements. i am up and out of bed and somewhat functional but life still really sucks and even with all this dopamine action going on, i feel like something is missing -- the drive and initiation and caring is so lacking, and the apathy, resignedness, hopelessness, givingup is so present.
I know i know, it's not all about neurochemistry. I'm doing the psychology stuff. My testosterone levels are low, trying to treat that as well.
But anyway THE QUESTION I HAVE IS:
Does anyone have experience with amineptine, compared to other dopaminergic agents? How does the subjetive experinece compare say between amineptine and bupropion, and compared to adderall or mirapex. Would I conceivably have to stop the stimulant if I tried amineptine?
Has anyone had good results with it? Or heard of anyone with good results?
I've tried MAOIs before, they help somewhat, but I have other problems with them.
7 years ago in college, I had so many ideas, ran a business out of my dorm room while getting three engineering degrees. Now at age 31, I fucked up the great job I had in technology, i am broke, living at home with parents and still can't find a job despite ivy league education because of my illness. So yeah, my apathy might be situational, but I'd like to think its more complex than that, and I know the amotivation killed my job performance.
Personally I think years of ephedra diet pills, then SSRI use fucked up my dopamien system pretty badly.
Also, last year I got highly addicted to PEA + MAOI...but that was the only thing that kicked the depression in the butt...at least before it caused hypomania and destruction, so I had to go off of it.
Anyway, please, any feedback would be appreciated.
