• Neuroscience & Pharmacology Discussion Welcome Guest
    Posting Rules Bluelight Rules
    Recent Journal Articles Chemistry Mega-Thread
    FREE Chemistry Databases! Self-Education Guide

  • N&PD Moderators: Skorpio

Alcohol strength to dissolve cannabinoids for injection

red22

red22

Bluelighter
Joined
Nov 23, 2009
Messages
2,079
Now as I understand it, cannabinoids are oils. As a test, I poured a little 70% isopropyl alcohol in a little glass jar and then poured some some sesame oil in. The sesame oil did not dissolve at all. Even after multiple vigorous stirrings, it remained a suspension like oil and water. So does alcohol need to be a certain strength for oil to dissolve in it?
 
I think that you're understanding "oil" in too narrow a sense; it just means a substance that is liquid at room temperature and hydrophobic. Sesame oil might not dissolve in isopropyl alcohol; THC certainly does. However, you need to examine the prudence of injecting cannabinoids given the purity of those you have access to, and the appeal of injecting a substance which, by all accounts, will not give a rush by that ROA.
 
Also, even if you manage to dissolve cannabinoids in the alcohol, injecting it would make it instatntly clog your blod vessel and block the hell out of it.

When injected, the mixture combines with H2O in blood and then cannabinoids doesnt dissolve anymore....

PS. Just dont do it unless it is a water-soluble cannabinoids.
 
Injecting is not a good idea. You could perhaps mix the cannabinoid with some warm milk (milk is an emulsion) and squirt it up your backside using a needleless syringe
 
I've come across one internet report of someone who intravenously injected straight Marinol (right here on Bluelight: https://tokecity.com/forums/showthread.php4?t=6775) and one report of soemone who intravenously injected crude marijuana using alcohol multiple times: https://tokecity.com/forums/showthread.php4?t=6775 So as soon as I get some syringe filters and everclear, I'm gonna try it.

Contrary to popular belief, the multitude of compounds in plant matter such as plant pigments and chlorophyll, etc, etc are negligible in your blood stream. Most of that shit probably gets in your blood stream by any other ROA anyway. It's not like intravenous injection is reserved for little bright white powders 8) Soak the weed in 70% isopropyl to take care of the bacteria, let it dry, prepare your shot with some everclear, and you're good.
 
Last edited:
This sounds like a horrible idea.

Strong alcohol solutions damage your veins. Weak ones won't dissolve the cannabinoids.

And in any case, most of the THC is inactive if it isn't heated to decarboxylate the THC-COOH to THC.

And why the hell would you inject it? IV is the riskiest ROA, and weed smokes real good, and there are well documented procedures for preparing it for oral use. There isn't a pressing need for it.
 
Because it's interesting seeing as how most other drugs can be injected. Time to break the IV barrier for weed.

Cannabinoids for the last time are not activated by heat. Moisture retains a carboxyl group in cannabinoids and absolutely thorough dehydration activates weed, not necessarily burning or boiling or whatever. Even if heat was necessary, heating could easily be incorporated into the prep of this. I really don't know why you brought that up as if it's an issue, hash for example if made properly is decarboxylated. A woman on Locked up abroad got stoned at the airport simply from swallowing cellophane wrapped pellets of hash as a result of hash residue getting on her fingers and touching all the pellets.


People bring IV marijuana up on various forums including this one from time to time; it's time foir someone to just fuckin' do this shit and be able to say yes, it works. As I pointed out, two experience reports already exist on the internet (see above post of mine) but they're a little lacking in details.

There isn't a pressing need for it? Well, excuse me but the concept fascinates me.

Marijuana and Cannabinoid Research (2006), on page 238 http://www.scribd.com/doc/14452038/M...-Research-2006 states that actual unmodified THC can be intravenously injected. The book states that it needs to be mixed with albumin or some other solubilizing agent. at another point in the book it essentially states that THC is kind of a bitch to inject. I interpret that to mean it's doable and as soon as I can get a syringe filter vand some ever clear and some high quality pot I'm gonna do it.

Other incentives of mine are heat may alter the molecular structure of cannabinoids. Injecting would perhaps give a pure, raw high. It would also be interesting to seec what the come-up is like via injection. And injection has a high (100%?) bioavailability whereas every other ROA for marijuana is notoriously low. It would be interesting to see how much stronger weed is via injection.
 
just because you can do something doesn't mean you should.

THC is usually injected as an emulsion in a carrier like sesame oil, however other than an exercise it is pretty pointless, as it will still rapidly distribute into lipids.

if a crude extract is used then the proportion of THC COOH present will have no effect, the THC content itself will be active, the conversion of THC COOH is caused by heating during smoking and is one of the many reasons why orally administered cannabis is down on potency compared to smoking.
the crude extract will also contains various terpenes and other components of uncertain effect and even if you get it sterile IV administration of the bacterial debris can lead to spectacular immune reactions.

just a dumb idea IMHO, there are other frontiers to explore.
 
How about using propylene glycol as a carrier/solvent instead? Im not encouraging anyone to do this and I think its quite silly injecting THC into your blood, but IMO propylene glycol seems more suitable than isopropyl alcohol.
 
You must log in or register to reply here.
Top