ferrett1979
Bluelighter
- Joined
- May 15, 2003
- Messages
- 1,181
Any info on this?
N&PD Moderators: Skorpio
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AL-NBOMe (NBOMe analogue of Allylescaline
ferrett1979
Bluelighter
Any info on this?
monstanoodle
Bluelight Crew
I shall send it forth over to ADD as they'll likely have more info for you
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I only know it's an analogue of an analogue of Mescaline.
EADD ----> ADD
p.s. Hiyer ADD
sekio
Bluelight Crew
Doubt it is active at all if it is what I think it is, i.e. N-(2-methoxybenzyl)-3,5-dimethoxy-4-allyl-PEA. NBOME mescaline is essentially inactive. I think the substitution has to be 2,5 dimethoxy for best results.
Regardless, titrating up is the best idea, ROA will probably be IM/IV > rectal > intranasal > buccal > sublingual > oral.
nuke
Bluelighter
The N-BOMe compounds appear to have a different binding pocket orientation than the 2C series, and so it seems that bulky 4-position substituents actually decrease affinity for 5HT2A/C.
The one I'm really curious about is the 4-F analogue, although maybe Erny and his comrades have already sampled this.
pharmakos
Bluelighter
NBOMe-AL might well be active, just at a much higher dosage than the ultra potent, sub-milligram NBOMe- drugs........
pharmakos
Bluelighter
^^ so about the same/slightly higher potency as compared to Allylescaline itself... a decent size potency increase when you account for the differences in molecular mass. i wonder how the two compare in effects... perhaps the NBOMe- is getting cleaved metabolically and the effects of this drug are purely from Allylescaline itself? might be true, might not, but it wouldn't be the first time such a thing has happened... check out the story of MDOH in PiHKAL
tryp2fun
Bluelighter
There is this tantalizing reference in Nichols' paper on the N-benzyls: Pertz HH, Rheineck A, and Elz S (1999) N-Benzylated derivatives of the hallucinogenic drugs mescaline and escaline as partial agonists at rat vascular 5-HT2A receptors. Naunyn-Schmiedeberg’s Arch Pharmacol 359 (Suppl 3):R29. This is an abstract from a conference. Unfortunately, I haven't been able to find the abstract on Arch Pharmacol's web site.
Bah, it was tested only up to 3,5 mg. I thought it was up to some tens of mgs. Then what you are saying may yet be possible.
I was told its active at 15mg
*dharmabum*
Bluelighter
Is anyone aware of anymore information (along the lines of trip reports etc. rather than academic papers) floating around on the internet?
I have a small sample of this that I got a while back but am too busy to be able to do anything with it in the foreseeable future and would be interested in reading more anecdotal information about it in the meantime - I know I'm not the only person to have a sample so there must be more people with experiences to share!