Advice please? Oxycodone & Benadryl

[littlethings533]

I have been on percocet for back pain for the last 2 years, every couple of months, my tolerance goes up and I need to be increased. I am trying to hold off asking for an increase until my next visit. I am currently taking 8 - 7.5/325 Oxycodone's a day. I am at the point where 2 7.5's doesn't do much. It lasts for about a half hour or and hour at BEST. SO -

Tomorrow morning I was thinking of taking a benadryl with my morning dose of 2 - 7.5/235's Oxycodones. Any advice on this? Will this help me? Will it potentiate my dose? or just make me sleepy? Will it feel euphoric? And is it safe to take together at the same time? I RARELY ever take benadryl, maybe once or twice in my entire lifetime.

Advice PLEASE!? I really want to not feel pain tomorrow morning, and I'm thinking Benadryl & Oxycodone together is my last option until my appt.

THANK YOU!!

 

[deadricbloodgod]

Benadryl if anything will just make it more sedating. Perhaps you should try grape fruit juice. That would help but is the only thing i can think of right now. And actually there is opiate potentiation(spelled wrong lol) thread. That's what you're looking for, search for it.

 

[vicodelicious]

Benedryl will only potentate the sedative effects of the narcotic. I don't think it will add anything to the analgesic properties to the oxycodone. Basically it will make you more drowsy and noddy.

Do a search and check out some chemicals that will do a better job of potenating the analgesic effects of the oxy.

 

[vicodelicious]

My suggestion... take 3 or 4 of your oxycodone/apap pills in the am. It will do more for you in the way of relieving pain.

 

[jackie jones]

You have been on your medicine long enough to have built a tolerance to it. This I believe is at the heart of your problem. Talk with your physician about an increase in dosage. Benadryl is only considered an 'opiate potentiator' by recreational users who use it to increase sedation. It will not increase the analgesic effect of your medicine. Grapefruit juice is a good option to potentiate the overall effects of oxycodone.

 

[Jabberwocky]

^agreed. the benadryl will only cause some drowsiness, not increase the effects of the oxy.

 

[PinK~cloud]

T-A-G-A-M-E-T is a life saver. try the stuff out some time.

anyway, 8 perc's at 325 apap a pill sucks. you really need to get on some high dose oxycontin instead of taking pill after pill all day. ask him about it.

 

[littlethings533]

Thank you so much for all your responses!!

I have in fact tried the GFJ thing, but I find it only works if you use it once in awhile, not daily. Plus I hear you should drink some about 30 mins b4 you dose? Is that correct?

And I do understand that this may not be the correct place for this topic, but I just needed some advice.

Also - last session with doc, I told him the meds weren't working anymore, I'm getting up in the middle of the night, can't sleep, the perc's only last for about an hour at best, then back in pain all day long. He said tht I have two options: "1 - switch me to a longer lasting opiate" (which he thought wouldn't be good because I was thinking of kids soon, which that is OUT of the picture. I can't have a kid if I'm going to hurt this bad. My husband REFUSES, let me say that again REFUSES to let me take ANYTHING, ANYTHING if/when I get pregnant. Anyways, that's a different story. My second option from the doc was try a different sleep med, which I knew from the get-go wasn't what I needed, but I figured, he was the doc.... so I tried it. Nothing. He also RX's me Flexoril 3x a day, which I'd say I've taken 2 in the past 6 months. It doesn't do anything, except put me to sleep.

So what's the next step up from Percocet 7.5/325's??

Also, the GFJ thing - how long before I dose, do I need to drink it? I can't remember.

 

[littlethings533]

T-A-G-A-M-E-T is a life saver. try the stuff out some time.

anyway, 8 perc's at 325 apap a pill sucks. you really need to get on some high dose oxycontin instead of taking pill after pill all day. ask him about it.

What does Tagamet do??

Yes it does suck taking that many a day. Does Oxycontin produce similar effects as oxycodone?? Does it just last longer? I find my perc's really help me with my concentration and patience as well as my pain..... well not right now lol.

 

[deadricbloodgod]

Tagamet inhibits the same enzyme that grapefruit juice does which means it just pontentiates it.
Yes OxyContin is not only similiar but actually is oxycodone. Yes it will last longer because it is the extended release form of oxycodone. Also *hint* the name, Oxycodone Continuous Release. But since it's continuous release(CR) you might have to raise the dosage as 15mg of CR will not be as strong as 15mg of Instant release. Also there are some others you should check out.
Look in this thread, like i said earlier.
http://bluelight.ru/vb/showthread.php?t=252569&highlight=opiate+potentiation
Oh and forgot but people suggest you should drink GFJ 45 minutes prior to dosing.

 

[Selfmeditaker]

As stated above somewhere, the problem lies within your tolerance that has built up over a 2 year period. If your taking 8 7.5/325mg a day I would suggest asking your doctor about putting you on maybe an ER med so you wouldnt have to take so many a day, it would also eliminate the 2600mg a day of APAP that your taking. Just a thought. Hope whatever happens works out best for you.

*cheers*

 

[littlethings533]

Thank you all for your advice.

I just have one more question. Being as this medication isn't working, I have bumped up my appt with my doctor to Monday. I simply cannot take it anymore, I need sleep and meds that work. When I was speaking with the receptionist, she said "well if you move up your appt, your medications aren't due until the tenth, so he won't be refilliing your meds until then". I don't know if this is just protocol for her to say that or what, but if I tell him AGAIN they aren't working (I told him this last time and that's why he switched the sleep medication and that was roughly 3 weeks ago. He told me to give it a month and come back.), do you think he will give me something else? or make me wait it out until the 10th?? Just curious and looking for a little hope thru all this pain.....

Also - is it wrong to ask for an increase in the middle of your prescription? or should you grin and bear it until your next refill??

Advice PLEASE!!

 

[Selfmeditaker]

^i do sympathize with your situation as it is a shitty one when someone who needs certain meds and has extreme difficulty obtaining them. However, we(bluelight) cannot tell you what your doctor will or won't do for you. It's between you and your doctor and its ultimately his decision when it comes to what meds he thinks you need. You do have a say in it as it is your health/well-being thats at stake here but as for us knowing wether or not its a good idea to ask for a bump up in dosage/ or a switch up in medications, during or in the middle of a 30 days supply, we really can't help you in that area. I would suggest that you just explain to your doctor what you have explained to us, be honest and listen to what he says and respect his opinions/ decisions and hopefully you guys can work out something that works for you.

Best of luck and I hope that you get things straightend out!

*Cheers*

 

[littlethings533]

I think my question may have been misunderstood. I am asking people's opinions, not precisely what my doctor would say or do. I am also not asking IF I should ask my doctor for an increase. I am asking if asking your doctor for an increase in the middle of your 30 day supply is a bad idea? I am asking to hear people's experiences and opinions.....

 

[jackie jones]

It would be best to express your concern about the amount of acetaminophen you are ingesting during your next appointment.

 

[TheMatador]

^
bingo

 

[Jabberwocky]

I am asking if asking your doctor for an increase in the middle of your 30 day supply is a bad idea? I am asking to hear people's experiences and opinions.....

well, you're going to get differentiating answers from different people. me, for example, i have asked my doctor for increases or extra scripts half way through the month without him having any problems of upping anything or writing extra scripts. mind you this was for codeine, tramadol and transdermal bupe patches which aren't considered too highly abused here in australia but has also been the same with valium. on the other hand when i've asked to have my fent dose upped he has told me to wait until the end of the month when my next script is filled out. it's going to depend case to case. if you have a good relationship with your doctor then i can see no harm in it because the worst you are going to be told is no. unless of course you come off as drug seeking

mrjackjones raised a good point you're going to want to address with your doctor about the amount of apap you're taking.

 

[littlethings533]

My suggestion... take 3 or 4 of your oxycodone/apap pills in the am. It will do more for you in the way of relieving pain.

If I do this, do you think the effect will last longer than the 1-1.5 hours it's barely working now? or do you think it will last the same amount of time and then I'll be stuck for another 10 hours until I can take my next dose. ????

 

[littlethings533]

well, you're going to get differentiating answers from different people. me, for example, i have asked my doctor for increases or extra scripts half way through the month without him having any problems of upping anything or writing extra scripts. mind you this was for codeine, tramadol and transdermal bupe patches which aren't considered too highly abused here in australia but has also been the same with valium. on the other hand when i've asked to have my fent dose upped he has told me to wait until the end of the month when my next script is filled out. it's going to depend case to case. if you have a good relationship with your doctor then i can see no harm in it because the worst you are going to be told is no. unless of course you come off as drug seeking

mrjackjones raised a good point you're going to want to address with your doctor about the amount of apap you're taking.

I definitely don't think I would come off as "drug seeking". I've been going to this doctor and this doctor ONLY for the past year and a half. I think that would be enough to establish that I am not "drug seekiing" especially due to the fact of the condition he knows I have (DDD and Arthritus).
Also - I am not out of meds, I can bring my remaining RX to him, that's not a problem. I have not "self-adjusted" my meds either. I went to him a few wks ago and he gave me the option to go on longer lasting stronger opiate (any ideas on what that might be??) or change up my sleep meds. I choose the sleep meds to avoid increasing anymore, but it's been about 3 weeks and I cannot take it anymore. He said to give it a month, but I can't take the no sleep and pain all day.

So given all that information, in your opinion, is it bad to ask for an increase or "breakthru" med in the middle of an RX?

 

[sarbanes]

Benedryl will only potentate the sedative effects of the narcotic. I don't think it will add anything to the analgesic properties to the oxycodone. Basically it will make you more drowsy and noddy.

Do a search and check out some chemicals that will do a better job of potenating the analgesic effects of the oxy.

Actually, antihistamines have opioid sparing effects, so in a sense, they do increase the apparent potence of a given amount of narcotic. you need less of the opioid/anti-histamine combo, than the straight narcotic alone. do a google scholar,