Advice on using oxymorphone?

[emkee_reinvented]

Mate - their will always be a minority who sell their scripts for street drugs. Methadone is not good medicine. Do you know the Dutch used to prescribe people with severe opioid addiction issues with bezitramide (Bugodan) which is a prodrug (so it MUST be swallowed to be active) and fairly replicated the H high for 12 hours.

Banned for political reasons.

1998 Dextromoramide was still in the Farmarcotherapeutisch Kompas, also a very powerful oral Opoid as good as IV Heroin.

Also dissappeared in the later edition's along with Meprobamaat and Clomethiazole.

 

[TheJuner]

Ok, sucked off the coating and cut the pill up. Insufflated around 2.5-4mg of oxymorphone and am starting to feel some effects. Pretty typical opioid warmth and euphoria, and analgesia.

T-0:20: Sniffed another 4 mg, 15 minutes after I’m feeling ridiculously high. Great sense of deep opiate bliss and warmth. Also took a few blinker hits from my cart so that probably contributes to how high I’m feeling.

T-0:40: Nodding hard, rubbing my body feels fucking amazing. I thought oxycodone was the most euphoric opioid high, and that nothing could surpass the state of warmth and total bliss and euphoria it causes. Oxymorphone is in a class of its own. And the sedation is even more intense too, it feels nice and dopey if that makes sense, which I think is really nice and desirable. It’s not as itchy either which I like as well, but certainly itchy. The itchiness isn’t dysphoric or excessive at all and feels quite nice

T-1:40: Rn I’m so ridiculously high. Genuinely the highest I’ve been on an opioid. It’s under 40 degrees outside and I’m unfazed walking with only a thin hoodie on. My pupils are the most constricted they’ve ever been too lol. I’m also nodding ridiculously hard but I can still walk.

T1:155: I take 25mg of Adderall XR, dumping the beads into an energy drink to offset some of the sedation as I’m hanging out with people and don’t want to nod off excessively. Still experiencing the warmth euphoria and analgesia too. It’s very intense and I feel on top of the world. My body is paradoxically heavy and as light as a feather and floaty. It’s so goddamn good. A side note, but I feel more easily annoyed. I rarely experience opiate rage, but the people I’m around are playing dogshit sounding music. I personally hate listening to this garbage. It’s metal from a local band that sounds fucking horrible and I do not feel like listening to it, it is intolerable for me.

T-2:20: My body feels as though it’s blissfully dissolving in unbelievably intense waves of opiate warmth and euphoria. It’s an incredible feeling, my mind feels at peace with everything and I feel extremely content and euphoric. Despite having ~240mg of caffeine over the past hour, it doesn’t overpower the sedating high of the oxymorphone. I feel amazing. Also feel a nice body buzz and stoning high from my cannabis oil pen, and am vaping nicotine which adds a nice dimension to the experience.

T-3:00: Still incredibly warm and euphoric and dopey, feeling intensely numb and warm in the body and serene and blissful in the mind. Smoked some wax in a dab rig too, feeling sooo high from the THC, like I’m floating and my body is glowing, just watching some Curb Your Enthusiasm and loving it.

T-3:20: Feeling the nice stimulant effects of the amphetamines too. Both a euphoric and creative mental stimulation and the tingly and tactile body high as well. Mixes very nicely with the opiate body high marked by warmth and euphoria and the body high of the weed too.

 

[Jen X]

Be careful and have fun

 

[deadhead4lyfe89]

@TheJuner so did you try yet? Fuck I forgot to mention I thought they may have discontinued Oxymorphone but idk probably wrong but if that's the case like Kief said, be careful could be fake, could be fentanyl, who the fuck knows...either way give us an update when you can!

It’s kind of more rare these days but there still are some people with legit scripts of it.The generic.The ones I’ve seen are green.i think they were 20mgs.
(& to the OG post,forgive me if someone already said but you lick the coating off. Then scape a little bit of stuff off with fingers. Then crush. They are hard at first but turn to powder. The green 20mg ones. But be careful it can be more potent than you realize & I usually wait longer if I’m gonna rail a lil more compared to my oxy railing speed)
But I wouldn’t trust anything from the street these days sadly ,unless I knew they had the script.

 

[Jen X]

What, Hydromorphone? And why is that? Is it because shooting pills is dangerous or bc of how addictive IV Hydromorphone is?

Both. I wish I never started iv'ing because now I'm having a hard time stopping. I get a script but I'm now buying from someone in the safe supply program and my tolerance is crazy.
So far this morning I've had 40mg iv and I should be on my ass but I'm not.
I wish I never started the needle

 

[swimmingbird421]

Lucky... freaking safesupply in USA would be a god send for me.
I can't wait to asylum to good ole Canada and get out of this mad house that's clearly on Fire.

 

[Jen X]

Lucky... freaking safesupply in USA would be a god send for me.
I can't wait to asylum to good ole Canada and get out of this mad house that's clearly on Fire.

You're moving to Canada? The process is long. I wouldn't unless you're prepared to pay 2k a month for a 1 bedroom apartment or 1 million for a house. If you can find one. Canada isn't like it used to be.
America isn't a country you can claim asylum for. It's for people fleeing war.
To immigrate regularly it's expensive and they are really picky. Can't have a criminal record

 

[Operia]

So I have some extended release oxymorphone tablets in my possession (they're 40mg tablets, the Amneal ones with the 'G74' imprint) and I was wondering what the best way to make use of these is. I am aware of the low oral bioavailability of oxymorphone, and plan on insufflating it, and as such I would like to know how y'all prepare these for insufflation given the extended release coating. It is my understanding that the coating can be sucked off. I don't have high opiate tolerance, as I don't use opiates frequently. For some perspective I usually use 15-20mg of oxycodone (I use oxycodone both intranasally and orally) to reach a deeply blissful and euphoric opiate high, though I don't nod off too hard and can still do things like get up and walk around usually. I also have used the aforementioned doses with other CNS depressants (generally a bad idea, I'm aware of that), most commonly a low dose of gabapentin between 300-600mg or about 5-10mg of cyclobenzaprine. I've combined the three before without issues. It has been about 12 days since I've last used opioids. So, given this information, how much should I snort? Tripsit says 5mg is a common dose, but according to my calculations (5*2*4=40mg oral oxycodone) this would be quite a lot. I'm curious as to what a good starting dose would be and would be appreciative if those who have used oxymorphone before would advise me.

You mention ’low bioavailability of oxymorphone’. Glucuronidation is also genetically diverse. I am fine with 5 mg orally. Why do you think snorting is more potent? It depends on your genetic glucuronidation factors (UGT2B7 isoenzyme/nucleotide). Are those isoenzymes more active in your nose?

 

[TheJuner]

You mention ’low bioavailability of oxymorphone’. Glucuronidation is also genetically diverse. I am fine with 5 mg orally. Why do you think snorting is more potent? It depends on your genetic glucuronidation factors (UGT2B7 isoenzyme/nucleotide). Are those isoenzymes more active in your nose?

Yeah, because oxymorphone only has an oral bioavailability of around 10%. Snorting is stronger because not only is the onset is significantly faster, but more importantly the intranasal bioavailability of oxymorphone is around 40%.

 

[Mayaman]

On top of my script i buy from someone in that program, they get 30 8mg pills a day. Blows my mind they sell it to buy that junk fentanyl/xylazine. I find IV hydromorph close to heroin.

We don't have oxymorph in Canada oddly enough

They buy fetty because the 8's do nothing. I can eat 35 and not feel anything and I haven't even done fet in months. Its so frustrating getting free drugs and cant even get a buzz. I wish there was something I could do to intensify these things.

 

[Opana313]

It’s kind of more rare these days but there still are some people with legit scripts of it.The generic.The ones I’ve seen are green.i think they were 20mgs.
(& to the OG post,forgive me if someone already said but you lick the coating off. Then scape a little bit of stuff off with fingers. Then crush. They are hard at first but turn to powder. The green 20mg ones. But be careful it can be more potent than you realize & I usually wait longer if I’m gonna rail a lil more compared to my oxy railing speed)
But I wouldn’t trust anything from the street these days sadly ,unless I knew they had the script.

Yeah I had the green 40 "extended release" which I treated as one and just swallowed.. but that badboy will break down after coating and crush..but I first tried this with the 40mg orange ones and fucking A your report is spot on..once you do that 2nd lil bit it's complete bliss.

Yeah, because oxymorphone only has an oral bioavailability of around 10%. Snorting is stronger because not only is the onset is significantly faster, but more importantly the intranasal bioavailability of oxymorphone is around 40%.

This has got to be spot on because my times dosing were the green oral and never did it smack like intranasal.

 

[Jen X]

They buy fetty because the 8's do nothing. I can eat 35 and not feel anything and I haven't even done fet in months. Its so frustrating getting free drugs and cant even get a buzz. I wish there was something I could do to intensify these things.

Orally they don't absorb much but ya they don't seem to touch fentanyl so they are starting to give people fentanyl patches and they need to return used ones to get new ones.
I wouldn't suggest IV but mixing them up and going up the back door is pretty close. You'll get more out of them

 

[Mayaman]

Orally they don't absorb much but ya they don't seem to touch fentanyl so they are starting to give people fentanyl patches and they need to return used ones to get new ones.
I wouldn't suggest IV but mixing them up and going up the back door is pretty close. You'll get more out of them

I tried that once with 15 and didn’t feel a thing. I’ve you can only do 4 or they gel a bit and clog. Tried to get liquid delautid or H but my dr says it’s not available in ont. I think he bullshits me sometimes. Told me they don’t do carries anymore so I have to go to pharmacy daily. Pain in the ass sometimes but how can you complain really. For some people it’s like getting a whole other cheque coming in. Maybe I’ll try to lower my tolerance this month.

 

[emkee_reinvented]

Mate - their will always be a minority who sell their scripts for street drugs. Methadone is not good medicine. Do you know the Dutch used to prescribe people with severe opioid addiction issues with bezitramide (Bugodan) which is a prodrug (so it MUST be swallowed to be active) and fairly replicated the H high for 12 hours.

Banned for political reasons.

Bezitramide sounds alot like dextromoramide, by name and effects. Till at least 1998 dextro-moramide could be prescribed, but had an red flag allready. So its was discouraged, now its long gone.

The reason stated was the irradic pharmakinetics, the same dose producing different effects at times. Death being the reasoning off course, could be a cover though, never trust a gouvernement and such.

But they do provide pharmaceutical Heroine, in a closed enviroment, only for the hardcore junk's at least a option.

sidenote i am repeating myself. Gonna look up that Bezitramide.

 

[smokeymcpot42088]

Both. I wish I never started iv'ing because now I'm having a hard time stopping. I get a script but I'm now buying from someone in the safe supply program and my tolerance is crazy.
So far this morning I've had 40mg iv and I should be on my ass but I'm not.
I wish I never started the needle

If you don't mind me asking roughly how long ago did you switch to the needle? It took me a few yrs of IV to get up to a 24 mg shot *which is admittdly wasteful; but tolrance is a bitch.

The shorter you use it and the less you like it the better your chances. Personally I hated it as I felt I was betraying my family and gf in a small way everytime I used. Two roving monitors and getting caught is embarassing af (too me).

If dilaudid is what you got the needle does kind of follow hand and hand, see if you can get a higher dose of something with better oral bioavailability?

uber protip, if the patches are NOT the gel one but the matrix one you can cut it up into little pieces, soak the pieces in rubbing alcohol, let it vap and you have about %90 of w/e fentanyl was in there in uber usable. (snort shoot boof w/e its a powder) .....Pretty sure fent is water soluble right?
(if you would like a source just say so and I will track It down) -- The matrix study not actual drugs of any kind. Just to be super clear.

 

[Jen X]

If you don't mind me asking roughly how long ago did you switch to the needle? It took me a few yrs of IV to get up to a 24 mg shot *which is admittdly wasteful; but tolrance is a bitch.

The shorter you use it and the less you like it the better your chances. Personally I hated it as I felt I was betraying my family and gf in a small way everytime I used. Two roving monitors and getting caught is embarassing af (too me).

If dilaudid is what you got the needle does kind of follow hand and hand, see if you can get a higher dose of something with better oral bioavailability?

uber protip, if the patches are NOT the gel one but the matrix one you can cut it up into little pieces, soak the pieces in rubbing alcohol, let it vap and you have about %90 of w/e fentanyl was in there in uber usable. (snort shoot boof w/e its a powder) .....Pretty sure fent is water soluble right?
(if you would like a source just say so and I will track It down) -- The matrix study not actual drugs of any kind. Just to be super clear.

I get ms cotin and hydromorph for break through pain. Just got a massive tolerance and to buy more it's cheap af. I only started with the needle about a year ago but haven't iv'd in a couple months now I think.

 

[Jen X]

I have MS so I take it daily

 

[smokeymcpot42088]

^ If you haven't IVd in a couple months you are probably ok. (on that spectrum). Lol let noone find out i guess is my best advice.

you arent shooting the ?herantyl? so you know your doses. Nothing draws up like dilly. Just be safe I guess.

It is always good news when I have no input!

 

[Opana313]

Orally they don't absorb much but ya they don't seem to touch fentanyl so they are starting to give people fentanyl patches and they need to return used ones to get new ones.
I wouldn't suggest IV but mixing them up and going up the back door is pretty close. You'll get more out of them

Are you saying that oxymorphone doesn't touch fentanyl patches? Just curious

Also curious about dillys and weĺl..ya..know..my anus....is this a bad idea for a dude mid 30s and usual tolerance is somewhere around 60(or 90mg)real oxy in one sitting intranasal?....nor quite one sitting on the last 30mg..I usually gauge it from there and end up intranasal 30mg more or 60mg more within 45mins-hour from that one sitting? Sooo like 90mg to 120mg all together within an hour to 1.5hr period.

A dosing question on boofing ^ Dilly..what would you recommend? Just 4mg 1st time? 2mg? Maybe 6-8mg?

 

[Jen X]

Are you saying that oxymorphone doesn't touch fentanyl patches? Just curious

Also curious about dillys and weĺl..ya..know..my anus....is this a bad idea for a dude mid 30s and usual tolerance is somewhere around 60(or 90mg)real oxy in one sitting intranasal?....nor quite one sitting on the last 30mg..I usually gauge it from there and end up intranasal 30mg more or 60mg more within 45mins-hour from that one sitting? Sooo like 90mg to 120mg all together within an hour to 1.5hr period.

A dosing question on boofing ^ Dilly..what would you recommend? Just 4mg 1st time? 2mg? Maybe 6-8mg?

No subs don't touch fentanyl.
To be on the safe side I would try 4mg first. You have a tolerance so you may need more but just do 4mg first and if after 20-30 minutes you don't feel much take a bit more. Don't take to much though, it is absorbed well in the booty and sometimes comes on slow.