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  • BDD Moderators: Keif’ Richards

Advice about dexamph + stomach meds (,also crash management)

Solipsis

Bluelight Crew
Joined
Mar 12, 2007
Messages
15,503
Location
NL
Hey do you guys know...

after a considerabe dexamph session, mostly orally dosed if your stomach feels fucked with, is it a smart idea to use remedies for that or not? I have already taken magnesium aluminum oxide as antacid but I also have ranitidine and omeprazole. I do know that ranitidine interferes with metabolism of other drugs and also that reducing gastric acid can enhance absorption of things like amphetamines. The session is discontinued though so there is nothing to be absorbed for now.

But tomorrow I have work, I'll try to just man up and sit out the crash but I especially want to keep residual stimulation and things like that under control. Which would require something calming like Ativan. But I'm not sure how well I will function being tired to begin with and also adding benzo sedation. So I am wondering what would be the best approach to survive till the weekend and also preferably being able to eat and rest enough.
Ranitidine is probably not a good idea if it can potentiate other things including benzo's, so I'm thinking omeprazole tonight?

Then tomorrow see what the minimum benzo dose is to avoid being tweaky and if it seems necessary to perform maybe a modest dex redose, then find the good balance between the stimulation and sedation.

I understand that combining uppers and downers is best avoided but if I feel I have to I'd rather stretch out the crash and make it milder but longer.

It will probably be alright, it's not that extreme - at least it doesn't seem like that yet... but I don't feel very confident about being able to sleep and sleep properly tonight and also have bad appetite which is to be expected. Yesterday evening I really ate too little but today I got my 3 meals.

This was a pretty bad idea (I had the day off today by the way) and also - isn't that so very typical - the session was ended far too late.

Hmm I guess I'd better make a thread of this post somewhere as well.

I'd really appreciate some input.

I just thought I'd put this here in BDD because a lot more people are visiting here than ADD.
Not sure where you mods would like to put this.
 
If your gut is hurting Solipsis I would go ahead and take whatever you need to get that under control. From my experiences with potentiating opiates, those substance really only have an effect if used before consuming the drug. And for the benzo use, I would use it sooner than later before you go to sleep and get some good sleep before work. A little grogginess from a small dose of benzo would be better than feeling strung out IMO.
 
Have you been eating? You could have acid build up and burning from it. Also do you take thses alot in any empty stomach?
 
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Amphetamine usage acidifies the PH levels in your stomach and in general makes your stomach feel like shit post use.

The best way to help this is to use alkalizing agents as you have stated. You are experiencing metabolic acidosis and an antacid will help greatly as will eating and sleeping.

Omeprazole will potentiate the effects of a benzodiazepine also.

I would recommend a non-sedating benzodiazepine like you stated and tonight using items such as valerian, first generation Anti-histamines or melatonin to help you sleep.
 
^I'm pretty sure she means eating.

Comedown management:

--Eat a nice filling meal.
--Drink some water or ideally something with lots of electrolytes (Gatorade, etc).
--If possible, take some magnesium supplements.
--Take a regular old multivitamin. Drink even more water with it.
--Take some vitamin C if possible. Fruit juices are also very good. Lots and lots of vitamin C, it helps speed the excretion of amphetamines from your system and is a powerful antioxidant.
--Take melatonin (3-6mg is good) - powerful antioxidant and helps reset your sleep schedule.

Chemicals:

--Benzodiazepines such as Ativan (lorazepam), etc. Are good and can help sleep.
--Sedating antihistamines are also usually pretty good. Doxylamine, diphenhydramine, promethazine, etc. All effective and can be mixed with benzos at recommended doses.
--Alcohol can help but its not recommended as much as the others.
--Cannabis, if it helps you with anxiety, can really help smooth out the comedown as well.
 
Antiacids can actually potenciate amphetamines but can help with your acid build up i gooe tou are able to get better soon and feel so sorry your stomach hurts i hope tou get better soon. And get a good night sleep tonight. Hugs

Also you are in the righthr place. add is more for advanced chemical questions here in bdd we are here for you. :)

Above is great advice I hope it helps :)
 
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Thanks a lot for the responses, I really appreciate it. It's 2:30 a.m. already though - these last few hours flew by like it was nothing.

I ate a terrible deep fried pizza, the bottom/crust was really tough especially hard if you have a hard time swallowing anything from sheer lack of appetite. I'm eating a pepper now for some added vegetables and fibers, have been taking vitamins throughout the day but I have let myself become borderline dehydrated now and then. Catched up with water later on.
My stomach is okay now actually, with one maalox alone (Magnesium Aluminum Oxide). Great, good to know that omeprazole also potentiates benzo's. I assume it's all competitive inhibition of cytochrome P450 then, but not entirely the same as ranitidine is it?

It's now too late to use sleeping agents since I don't have the needed 8 hours left on the clock for something like zolpidem. Midazolam had also been a great possibility, really strong stuff.
Well I guess it will have to be diazepam, and hope for the best. I don't feel the least bit sleepy now, again very unsurprising.
I do fear though, that if the dexamph is metabolized a little further tonight if I take an excess of diazepam there is less stimulation tomorrow morning to help me wake up. I fear sleeping right through my alarm clock.
Shorter acting benzo's like lorazepam / Ativan, I have plenty of but it works primarily on anxiety and fear, not sedation and sleep (hypnotic effect).
Same goes for bromazepam.

Oh, I got it! - I'm switching to alprazolam for tonight, just popped 0.5 mg so you see I'm not going overboard with the benzo's. I've been running very low on alprazolam for a long while now. Didn't really matter anymore anyway - I am currently doing a tapering schedule with diazepam. Unfortunate that this messes it up a bit but it shouldn't take long to fix.
Alprazolam is not *that* physical either, but it's still an all-round very good one and the duration of effect matches nicely for this situation.

About metabolic acidosis: I don't think you got that right, acidosis is when your blood gases and acidity are all out of whack, why would that be? We're talking stomach acidity here. The amphetamines irritate the lining of the stomach and too much gastric acid hurts when it is sensitive. Which is why part of it is now neutralized.
Metabolic acidosis is either when your kidneys are messing up and stop keeping your blood acidity in check, or from another cause.

I had it once caused by severe hyperventilation when I had my first panic attack. I thought I became less and less able to maintain normal respiratory rate, it even felt like I started losing control over muscles that allow me to breath. In reality though I could breath just fine. So I started overcompensating and this was so extreme (and also quite some time passed) that my longs were absorbing a lot of CO2 from the air. This turned into carbonate in my blood making it acidic. This gave me acidosis which (almost ironically) resulted in very real physical effects including chest pain and fluttery feelings in my chest, my breathing started feeling almost even more weird. Also the hypoxia can apparently have psychoactive effects. While I still had not come down from my own psychoactive effects from 4-AcO-DMT among other things.
So landed me in the ER, I walked to the entrance 4 times, then 3 times back home because I started feeling better being outside and calming down, riding a bike or whatever... then back at home it would all start from the beginning so the 4th time I checked myself in. Fuck hyperventilation.

Anyway I'm cool now, only problem is that I am not in bed. Hmm 3 a.m. - work doesn't start until 10 a.m. though and it's only a 5 hour shift.

I heard no reaction regarding redosing to combat the crash. I never do this with alcohol, when I start getting a hangover my appetite for more alcohol is just gone. But with dex it's different: it can postpone some tiredness and loss of concentration so I'm thinking about the major drawbacks?, if I feel this is my best bet to make it to the weekend I'd start carefully with like half a 5 mg dex pill with an option on the other half.
And since I will be at work, I will think twice before I start popping more, too much, then tweak. Best is not to bring more than bare minimum.

Well better option than coffee or other things with caffeine in it, right? I'd get shakey long before I expect it to give me some proper energy that weighs up to the situation.
 
In response to this:

If your gut is hurting Solipsis I would go ahead and take whatever you need to get that under control. From my experiences with potentiating opiates, those substance really only have an effect if used before consuming the drug. And for the benzo use, I would use it sooner than later before you go to sleep and get some good sleep before work. A little grogginess from a small dose of benzo would be better than feeling strung out IMO.

Yeah thanks for your thoughts and advice :)

Time is still flying by, I am typing way too long posts everywhere..

My stomach has settled, the Maalox (antacid) helped quite a bit and what discomfort remained disappeared when I ate the most terrible deepfrozen pizza of all time. That was hours ago. I just ate a pepper for some extra vegetables and fiber, and I have been taking vitamins all day.

You can check the thread I have running below, where is explained why the other stomach meds would not have been a good idea so I'm glad I did not take any of those.

http://www.bluelight.ru/vb/threads/609547-Advice-about-dexamph-stomach-meds-(-also-crash-management)

Was unsure what to do about the question of benzo's, like which one and how much etc... I don't want to sleep through my alarm clock but short acting ones like lorazepam virtually don't help with sleep. Same for bromazepam. But I got a few stashed alprazolam left so I just took 0.5 mg of that. I think I'm gonna need that other 0.5 mg. Hard to put a dent in this persistent 'speeding'.

The major question for me now is:
What is acceptable regarding dosing dex again, a bare minimum to keep the motor running for a shift that is only 5 hours...
?
I wonder if it will mostly increase side-effects like residual stimulation and tweakiness. Like talking too fast then stumbling over your own words.

IMO it will be a little tightrope walking to make sure I am not too obviously tweaky and can just shrug it off as insomnia -
but also making sure I am not tóó benzo'd up, getting a little vague, or worse: becoming tired and sleepy.

Of course it's ideal if I can find a proper balance and solution that involves the least possible amount of extra pharms.

For a number of hours now I am getting typical sleep deprivation visuals, though not the paranoid kind like seeing movement in the corner of your eyes. Instead it's more like cannabis visuals. Fuck, I do hope I can act more or less normally in the morning.

Yes, I expect that you will say: 'get some sleep, man!' :)
and yeah you're right, but every post I type becomes a long one and I feel like it's just not happening, no way jose. I'm wide awake.
So here comes the rest of the alpra, let's hope things settle down soon.
 
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