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Advanced compound formulation pronunciations.

Nagelfar

Nagelfar

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OK, due to the content I could not decidewhether this is rightly a basic or advanced discussion topic but I'd figure only the advanced would know as we're touching on advanced terminology of the advanced chemistry nomenclature. I understand beta & gamma etc., the Greek letters, but when a chemical name looks like this:

(-)-2β-(3-(4-Methylphenyl)isoxazol-5-yl)-3β-(4-chlorophenyl)tropane

How would the "(-)-..." be pronounced when spoken word., etc. for example?
 
Just say "L" for minus, "D" for plus and racemic when the signs are stacked together.
 
Ah I didn't know it was Levo contra Dextro.

So other than that the continuing brackets are in that same vein and the dashes are for simplicity of viewing the name delineation?

I suppose if no one can come up with more advanced type discussion for the word formulations of scientific naming conventions and how they are said this thread may be better moved elsewhere, I wish not to be responsible for clutter on the Advanced Drug Discussion (if alas even I already am I hope to minimize)
 
seep said:
Just say "L" for minus, "D" for plus and racemic when the signs are stacked together.
Click to expand...

There is no direct correlation between the rotational direction (indicated with + and -) and the relative stereochemistry (indicated with D and L)!

dread said:
L / D system is different than levo/dextro system.
Click to expand...
D = dexter (latin for 'right') and L = laevus (latin for 'left').
These get very often confused with the small letters d/l, which are synonym for +/-!

And to answer the original question: You would pronounce them simple as the mathematical descriptors that they are:
+ = "plus"
- = "minus"

What one should distinguish is:
- D/L-nomenclature for describing the relative stereochemical configuration (acc. to Fischer; outdated and almost exclusively used for sugars and amino acids nowadays)
- R/S-nomenclature for describing the absolute stereochemical configuration (acc. to Cahn, Ingold, Prelog, therefore called "CIP"-system, too. The most up-to-date nomenclature for describing stereochemistry)
- +/- nomenclature for describing if a chiral compound rotates the plane of polarized light clockwise (+) or counter-clockwise (-).

Peace! - Murphy
 
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dread said:
L / D system is different than levo/dextro system.
Click to expand...

Yeah but if I wrote the lower case ell, it would look ambiguous:

1-alanine
I-alanine
l-alanine

all look identical on my browser.

As a side note, "minus alanine" is something I've never heard anyone say.

edit: Never mind my last sentence. I just realized that by "anyone" I meant doctors, nurses and biology professors.
 
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1 looks identical to I and l on your browser? I can't believe this. I went through every type face I have, and not a single one. Not IE, Firefox, Netscape, Chrome, Opera or Safari (had to use my mom's mac to make sure of this) default to this.

so either you're full of shit, or you're using a font that no one in the world uses.
 
Hammilton said:
1 looks identical to I and l on your browser? I can't believe this. I went through every type face I have, and not a single one. Not IE, Firefox, Netscape, Chrome, Opera or Safari (had to use my mom's mac to make sure of this) default to this.

so either you're full of shit, or you're using a font that no one in the world uses.
Click to expand...

No full-of-shit-titude. In the browser proper, the lowercase ell and uppercase eye are identical (a vertical line). In the TYPE MESSAGE box, the one and the lowercase ell are identical (vertical line with a full serif beneath and a half serif above). The question was about pronunciation, not meaning.

Edit: browser is Chrome, typefaces are I dunno. re my original comment: I should've spelled out the sounds.
 
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What browser? what type face? scanning through the browsers I have on this, and I don't have to work to get, and the font you're posting in, that's not true. I l 1 are all substantially different in those. The point was that D/L =/= d/l, which regardless of pronunciation, matters when you're typing. If you were talking, it wouldn't matter. When you're typing though, it does matter.

it seems like a silly lie to cover a minor mistake.
 
Hehe, of all the things I've seen a thread run off course to degenerate in to... I have never, ever, once seen a thread turn into a debate about whether a user is lying or not about what font they're using, and be in all earnest. Rather amusing. ;P
 
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