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ACTH inhibition caused by opiates, better immune system? healthier individual?

i are spectre

i are spectre

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Is this notable for all opiates? The more I've been reading, I see morphine, loperamide, etc inhibiting ACTH. Less ACTH would inhibit glucocorticoids' release from the adrenal cortex. Wouldn't that mean lower blood pressure, more white blood cell production, faster tissue repair, and an overall better immune response? After a while, I suppose one would receptor-regulate to make up for the imbalance, but initially isn't that what we are looking at?
 
I know heroine junkies are for sure some of the healthiest, longest living, people I know.
 
I've noticed that I never really seem to get sick when I'm using even when my whole family has a cold or flu, when I'm not using I'm usually the first to get sick. I've always wondered if it was just because the junk was just masking the symptoms or if there was something more to it.

I remember seeing a thread somewhere else about this topic but unfortunately im not familiar with the science behind it that you posted.
 
that's the question of the day.

if one were to take the exact same amount of opiates every day, then yes, i would assume good ol homeostasis would cause down regulation.

but it's not really direct inhibition (adrenocorticotropic hormone), and the exact mechanism behind it i just can't seem to find.

i've been an avid opiate user for years, daily. i've also never found myself sick in these times at all (except when im out, which is extremely rare). each time i use opiates, i feel the effects of them, it's not just to feel normal (minus the couple years of suboxone maintanance which i have finally broke away from). so if one feels the high, then there must be be enough opiates to cause the usual opiate effects, and apparently one of them is corticotropin inhibition...

...and with that comes decreased cortisol (and aldosterone) mostly, cortisol being a primary stress response hormone. stress is being linked to more and more problems every month it seems... high blood pressure, illness, depression, cancer, and many others.

it seems that opiates reduce stress, not only psychologically, but physiologically via hormone response.
 
hah!

http://opioids.com/morphine/acth-assoc.html

http://www.ncbi.nlm.nih.gov/pubmed/6294717

our endogenous pain killers inhibit the stress response. exercise would be a good way to promote these. opiate users are bypassing this mechanism and at the same time inhibiting cortisol and adrenocorticotropic hormone. thus basically promoting a healthy internal environment with good ol fashion dope! literally nodding out and manufacturing leukocytes like nobodies business! now if only certain drug addicts can take part in better lifestyle choices, theyll be facing a longer, healthier life!

opiates are good for you. you just have to make good choices with diet/hygiene and you will, in theory, live a longer and healthier life.

now its time to dig into ADDERALLS affect on corticotropin and cortisol...
 
Have you ever have any kind of habit?

Opiates are not good for you.

If you want to discuss whether or not ACTH inhibition is good long term or not, and what substances are ACTH inhibitors to find a suitable one, I think those would be worthy pursuits.

But if you are going to try to convince the world that opiates are good for an otherwise healthy individual, they are going to think you are insane.
 
i've had a habit for about 10 years now. a good 5 of which have been daily use. i'm not proud of it, probably because of the social stigma associated with it, but i enjoy almost every moment of my life.

and yes, almost everyone thinks i'm completely insane. thanks for your input.
 
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