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Acid base extracton , acetic acid and baking soda
- Thread starter DylanG204
- Start date
sekio
Bluelight Crew
Aqueous HCl and lye are not "controlled chemicals". They can almost always be bought in small quantities at e.g. pool supply stores, hardware stores, or even some "lab supply" or "science supply" companies.
If you can somehow get glacial acetic acid but not HCl/Lye, you should rethink doing an extraction... I know that baking soda is not enough of a strong base to extract DMT in good yields witout making a soapy muck.
You shouldn't need to do a psilocybin extraction with HCl/Lye, make lemon tea with mushrooms and drink that.
If you can somehow get glacial acetic acid but not HCl/Lye, you should rethink doing an extraction... I know that baking soda is not enough of a strong base to extract DMT in good yields witout making a soapy muck.
You shouldn't need to do a psilocybin extraction with HCl/Lye, make lemon tea with mushrooms and drink that.
Thanks for the info , i am interested in obtaining pure chemical not lemon tek.
i have no room for fruiting my mycelium cakes , so i just grow the cakes.
i have extracted 50 grams of dried mycelium and got an unknown quantity of a very oily substance , ( is this because psilosiben is an oil in freebase ?)
i have no room for fruiting my mycelium cakes , so i just grow the cakes.
i have extracted 50 grams of dried mycelium and got an unknown quantity of a very oily substance , ( is this because psilosiben is an oil in freebase ?)
sekio
Bluelight Crew
The chemical is spelled 'psilocybin' - and would be hydrolised to psilocin in acid solution.
Psilocybin has a melting point of >200 degress, and psilocin freebase melts at ~170 degrees Celcius. Your extraction was probably just a fuckup.
As far as I know mycelium cakes don't contain high levels of alkaloids like the fruiting bodies do, you need to fruit the cakes for maximum yield.
The best way to extract psilocin and psilocybin from mushrooms seems to be stirring for 12h in pure dry methanol (methyl alcohol) or in vinegar (5% acetic acid in water). Do be advised that to get pure compounds you would have toi perform a chromatographic seperation - otherwise you will simply have a mushroom extract of psilocin/psilocybin'/baeocystin. (Tl;dr - You don't need to do a full acid-base seperation.)
Psilocybin has a melting point of >200 degress, and psilocin freebase melts at ~170 degrees Celcius. Your extraction was probably just a fuckup.
As far as I know mycelium cakes don't contain high levels of alkaloids like the fruiting bodies do, you need to fruit the cakes for maximum yield.
The best way to extract psilocin and psilocybin from mushrooms seems to be stirring for 12h in pure dry methanol (methyl alcohol) or in vinegar (5% acetic acid in water). Do be advised that to get pure compounds you would have toi perform a chromatographic seperation - otherwise you will simply have a mushroom extract of psilocin/psilocybin'/baeocystin. (Tl;dr - You don't need to do a full acid-base seperation.)
i used 99% isopropyl ,
i know they dont have as much as the fruit , but i have hundreds of grams of dried mycelium wich is more than enough for a few doses.
i need an acid base extraction too seperate the plant materials from psilocin/psilocybin'/baeocystin, as i want a clean white pure product
i know they dont have as much as the fruit , but i have hundreds of grams of dried mycelium wich is more than enough for a few doses.
i need an acid base extraction too seperate the plant materials from psilocin/psilocybin'/baeocystin, as i want a clean white pure product
sekio
Bluelight Crew
You are not going to get "clean white product" with an amateur level extraction, sorry.
From your other thread:
Do some research on your own next time before you decide to waste everyone's time asking silly questions.
Psilocbyin is a water soluble phosphate ester of psilocin that comprises most of the weight of the mushroom's active alkaloids. Psilocin is the water-insoluble counterpart that is present as freebase, usually less than 1/10 the mass of psilocybin. Baeocystin is the N-desmethyl version of psilocin, & behaves like an analog of psilocin with regards to solubility.
Freebase mushroom alkaloids should be white crystalline material as either salts or as freebases. They are not "goo" or liquid.
Have you even tried eating the mycelium to see if it is active?
From your other thread:
Do some research on your own next time before you decide to waste everyone's time asking silly questions.
Psilocbyin is a water soluble phosphate ester of psilocin that comprises most of the weight of the mushroom's active alkaloids. Psilocin is the water-insoluble counterpart that is present as freebase, usually less than 1/10 the mass of psilocybin. Baeocystin is the N-desmethyl version of psilocin, & behaves like an analog of psilocin with regards to solubility.
Freebase mushroom alkaloids should be white crystalline material as either salts or as freebases. They are not "goo" or liquid.
A. Shulgin said:
Have you even tried eating the mycelium to see if it is active?
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Jesusgreen
Bluelight Crew
Merged your two threads. 
DylanG204:
Since your PM inbox are full, please delete some messages if you would like me to answer your questions
Or contact me PM with your email maybe..
Regarding extraction of DMT, you don't wan't to do an acid/base extraction - you wan't to do a straight to base extraction(No acid)
Edit: Here's one guide; https://mycotopia.net/forums/botanicals/55697-first-dmt-extraction-stb-w-pics.html (Think you have to create login to view pictures)
//blazR
Since your PM inbox are full, please delete some messages if you would like me to answer your questions
Or contact me PM with your email maybe..
Regarding extraction of DMT, you don't wan't to do an acid/base extraction - you wan't to do a straight to base extraction(No acid)
Edit: Here's one guide; https://mycotopia.net/forums/botanicals/55697-first-dmt-extraction-stb-w-pics.html (Think you have to create login to view pictures)
//blazR
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"Psilocbyin is a water soluble phosphate ester of psilocin that comprises most of the weight of the mushroom's active alkaloids. Psilocin is the water-insoluble counterpart that is present as freebase"
just because psilocbyin is the phosphate ester does not mean it is naturally attached too an acid, wouldent both psilocbyin and psilocin both be freebase and both be in oil form?
If i wanted too get the powder i would halfto form a hcl or furmrate salt and extract from the natural plant material.
No i have not eaten the cakes but i have let them mature for a long time , I will go to my local chem supply store and post the results of my theory
just because psilocbyin is the phosphate ester does not mean it is naturally attached too an acid, wouldent both psilocbyin and psilocin both be freebase and both be in oil form?
If i wanted too get the powder i would halfto form a hcl or furmrate salt and extract from the natural plant material.
No i have not eaten the cakes but i have let them mature for a long time , I will go to my local chem supply store and post the results of my theory
http://www.fanaticus.com/mycoalki.htm
cheak out this link , they performed extractions on both mushrooms and mycelium ,
I think they are leaving out key information as other drug manufatruing teks do . I think they also performed a cloroform / naptha wash with an acid base extraction
as i got an oily , non powdery susbstance just using isoprpyl
quote "By Searcher (Novice) on Monday,
November 18, 2002 - 05:05 am: Edit
As I recall, there were about 6 or 7 jars that seemed to have good mycelial development, but colonization was very uneven, or so slow, that I abandoned them to put better jars in my grow chamber. Rather than just tossing out the slow jars, I decided to break them up and try Prof. PF's extraction technique. By the way, the alcohol seemed to absorb a lot of water from the air - it no longer smelled of alcohol, and the drying process slowed down a lot just before the amber tar and then the crystals appeared. I used no heat, but kept a large fan blowing on the liquid over a large, shallow cookie sheet.
--------------------------------------------------------------------------------
By Searcher (Novice) on Tuesday,
November 26, 2002 - 12:53 pm: Edit
Behold, cystals - little white snowflakes - just using 99% isopropyl--- "
cheak out this link , they performed extractions on both mushrooms and mycelium ,
I think they are leaving out key information as other drug manufatruing teks do . I think they also performed a cloroform / naptha wash with an acid base extraction
as i got an oily , non powdery susbstance just using isoprpyl
quote "By Searcher (Novice) on Monday,
November 18, 2002 - 05:05 am: Edit
As I recall, there were about 6 or 7 jars that seemed to have good mycelial development, but colonization was very uneven, or so slow, that I abandoned them to put better jars in my grow chamber. Rather than just tossing out the slow jars, I decided to break them up and try Prof. PF's extraction technique. By the way, the alcohol seemed to absorb a lot of water from the air - it no longer smelled of alcohol, and the drying process slowed down a lot just before the amber tar and then the crystals appeared. I used no heat, but kept a large fan blowing on the liquid over a large, shallow cookie sheet.
--------------------------------------------------------------------------------
By Searcher (Novice) on Tuesday,
November 26, 2002 - 12:53 pm: Edit
Behold, cystals - little white snowflakes - just using 99% isopropyl--- "
Look at the link i provided , look how "clean" their product is .
as long as i get crystals (even if its 50-60 %pure) crystals are all im trying too get , having limited chemistry knowlege would the process i desxribe yeild a relitivley pure product?
By Searcher (Novice) on Sunday,
December 08, 2002 - 02:55 pm: Edit
Here are the results from my first methanol soak:
Yielded 3.85 grams of crystals from 8 ounces of mycelium. But wait, there's more! Remember we're doing three, consecutive soaks. Looks like we'll be getting even more residues out of soaks 2 & 3:
Miscellaneous notes on the methanol: You'll note that this residue us lighter in color than residue gleaned from the water soaks. Also, this residue comes out dryer - no intermediate "tar" stage.
"
as long as i get crystals (even if its 50-60 %pure) crystals are all im trying too get , having limited chemistry knowlege would the process i desxribe yeild a relitivley pure product?
By Searcher (Novice) on Sunday,
December 08, 2002 - 02:55 pm: Edit
Here are the results from my first methanol soak:
Yielded 3.85 grams of crystals from 8 ounces of mycelium. But wait, there's more! Remember we're doing three, consecutive soaks. Looks like we'll be getting even more residues out of soaks 2 & 3:
Miscellaneous notes on the methanol: You'll note that this residue us lighter in color than residue gleaned from the water soaks. Also, this residue comes out dryer - no intermediate "tar" stage.
"
Each 100 grams of dried mycelium should yield about 2 grams of extracted material. This should contain at least 500 mg of psilocybin/psilocin mixed or about fifty 10 mg doses. Theoretically psilocin should have the same effect upon the user as psilocybin. The only difference between the two is that the later has a phosphate bond which disappears immediately after assimilation in the body. In other words, in the body psilocybin turns into psilocin. Psilocybin is a fairly stable compound, but psilocin is very susceptible to oxidization. It is best to keep the extracted material in a dry air tight container under refrigeration. A sack of silica-gel can be placed in the container to capture any moisture that may enter.
you can't do acid base extraction on shrooms, the base will destroy the product.
The "crystals" shown in that tek are not actually Psilocybin. They will test negative for the good stuff with Keller’s reagent and do nothing but give you an upset stomach. The gooey oily stuff is what they talk about packaging up. To actually crystalize this chemical you will have to run through a Cellulose column using water and butyl alcohol, then remove halides with an expensive silver based chemical. There is a paper on performing this on shroomery I think. You are probably looking at least $400 in equipment and chems. Why bother, the gooey stuff works great, almost no nausea if you put it in capsules. If you can, do the extraction with Everclear rather than Methanol, it’s not that much less efficient and you don’t have to worry about going blind if you don't evap all of the methanol.
The "crystals" shown in that tek are not actually Psilocybin. They will test negative for the good stuff with Keller’s reagent and do nothing but give you an upset stomach. The gooey oily stuff is what they talk about packaging up. To actually crystalize this chemical you will have to run through a Cellulose column using water and butyl alcohol, then remove halides with an expensive silver based chemical. There is a paper on performing this on shroomery I think. You are probably looking at least $400 in equipment and chems. Why bother, the gooey stuff works great, almost no nausea if you put it in capsules. If you can, do the extraction with Everclear rather than Methanol, it’s not that much less efficient and you don’t have to worry about going blind if you don't evap all of the methanol.
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