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acacia rigidula - natural amphetamines??

Certain dextroamphetamine containing pharmaceuticals contain "acacia" as an excipient; could this, in fact, be an undercover pharmacon?
 
Adrenochrome said:
Certain dextroamphetamine containing pharmaceuticals contain "acacia" as an excipient; could this, in fact, be an undercover pharmacon?
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no almost all acacia is inert in any psychoactive regard and indeed acacia is VERY widely used as an excipeint, filler, gelling agent , and other benign uses
 
nanobrain said:
the Wattle is the botanical emblem of Australia
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'This here's the wattle,
The emblem of our land,
You can stick it in a bottle,
Or hold it in your hand'

Sorry, couldn't resist :)
 
LuxEtVeritas said:
what else is found in nature other than ephedrine that contains an alpha-methylation on a PEA structure?

and if looked for in the low ppm is there any possibility in any ephedrine containing species to find amphetamine structures (desoxyephedrine or desoxynorephedrine , et al)?
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In Khat, there is cathinone (beta-keto-amphetamine) and the N-desmethyl analogue of ephedrine (cathine).
 
morninggloryseed said:
In Khat, there is cathinone (beta-keto-amphetamine) and the N-desmethyl analogue of ephedrine (cathine).
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duh, right i forgot about that

But still no non-beta "adulterated" alpha-PEAs....hmmmm....wonder why....is it that all these plant make beta-OH or OXO -PEA prior to alpha methylation
 
LuxEtVeritas said:
duh, right i forgot about that

But still no non-beta "adulterated" alpha-PEAs....hmmmm....wonder why....is it that all these plant make beta-OH or OXO -PEA prior to alpha methylation
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it is really rather unlikely that anything adds the alphamethyl to something.

there is a shortage of natural enzymes that cleave benzylic OH I can't think of any, (there are plenty that reduce oxo to hydroxy,)so I don't expect amphetamine or its congenersto be naturally occuring anywhere.
 
I noticed that eradication of the plants was proposed. Does anyone think that this might be related to an agricultural motive to gain more arable land and possibly side-step regulations about deforestation? I don't know much about the enironment around there, but I do know something about human nature.
 
Uh obviously there's an agriculture motive if it's causing ataxia or w/e in livestock........................
 
I'm not super familiar with the area, but I'm pretty sure it's not an invasive species.
 
Acacia study at A&M Texas

i'm in texas and am from texas.
the study published from texas a&m is quite probably accurate. unless someone cannot duplicate it, there is no reason to doubt it. the agriculture department there is very academic, and as a landscaper/gardener, i have found their information to be quite reliable. the eradication program was probably initiated because this study concluded that these 2 acacias are poor fodder for cattle and other livestock. another trait of this ag department is to be narrow-minded in that way. i do not know that the eradication program has extended to public lands, and the A. berlandi is sometimes available in this area in plant nurseries, as an ornamental for xeiric landscapes. i have yet to seek out the A. rigidula, but will post again after i get to that.
 
Again, these small trees grow in the arid western part of texas and farmers and ranchers can already cut them down at will. so i really don't think that there are any deforestation policies to get around, concerning these acacias. however, if there were, i wouldn't be surprised to see something like hussness suggested.
 
Wikipedia has also some information about the substances in acacia rigidula:

Phytochemistry

A 1998 paper in the journal Phytochemistry indicates that the leaves and stems of A. rigidula contain 40 alkaloids and amines, including:

* 3,4,5-Trihydroxy-phenethylamine (demethylated mescaline)
* Methamphetamine
* Anhalamine
* Beta-methyl-phenethylamine
* Catechin
* Dimethyltryptamine
* Fisetin
* Hordenine
* Mescaline
* N-Methyltryptamine
* Nicotine
* Nornicotine
* Phenethylamine
* Quercetin
* Tyramine
* Tryptamine
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Look at that list. Is that even remotely plausible? This has to be contamination in the lab that conducted the study.

ebola
 
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