Wow, awesome thread! I'll try to share my experiences as succinctly as possible, but it'll still probably be long-winded. I apologize in advance. I really enjoyed reading everyone's posts and would like to contribute my story.
*I did not expect this to be as long as it was. TL;DR. I got sucked into it because it's really cathartic to divulge this story in such explicit detail. I'll put some bullet points after the end of the demarcated area if you wanna skip this verbose and probably poorly-structured mess of a post.
![Stick out tongue :p :p](data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7)
Honestly, I got so much out of this just from writing it.
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Prior to any drug use, I had been diagnosed with chronic depression and severe anxiety, including panic attacks. I was even on medication before the age of 10. Both sides of my family are rife with similar mental disorders as well as addiction. Interestingly enough, my dad was a heavy user of stimulants, particularly MDMA. He even was a partial owner of a very popular nightclub in the Dallas area when the ecstasy/rave scene was really starting to gain traction in the 80's.
I started taking MDMA in the form of tablets at the age of 16 (not medicated at this point). My comedowns would be pretty rough, but they were bearable. And oh how I loved rolling. I remember how acute my mental craving for the ecstasy high was, and I continued to do it throughout high school for another 15-20 times with a relatively decent amount of time between each roll. The only reason I didn't use it more was because there was a huge bust in our area, and there was a time when most product being sold was either bunk or super hard to come by, even at clubs. Not to digress, but the scarcity of tabs is what actually led to my using meth (I had only taken Rx amphetamines before and loved them, so my meth use was a sufficient distraction from rolling).
In mid 2008, I went through a period where I was rolling very frequently with very little time separating uses. I was young and reckless, so I didn't take any sort of precautions when it came to ecstasy because I was more concerned with getting the high than being safe. My heaviest use was over a three month period where I was taking anywhere from 2-10 tabs at least four times a week. At this point in my life, I didn't have a job and wasn't going to school, so I would find myself popping tabs right when I woke up. No other substance was an adequate replacement. Alcohol has been my most consistent DOC, but I'd get drunk and immediately go on the hunt for tabs if they weren't immediately available.
As is to be expected with frequent use, ecstasy was beginning to lose its magic and my comedowns were getting worse. I was prescribed an SSRI before I really started going on my binge, but I obviously wasn't taking them because they interfere with the effects of ecstasy. My comedowns were so profoundly dark. I'd close my eyes and see incredibly disturbing visuals. I was also having auditory and visual hallucinations induced primarily by lack of sleep, but I know constantly depleting my brain of chemicals and not allowing for their restoration wasn't helping my situation. I was still rolling a lot, but I cut back use to one or two times a week (still high dosages, but I can't be specific) so I could roll harder. Heh, I thought I was actually using self-restraint. I was also using 5-htp and taking my remaining anti-depressants when I could between uses. I would take my medication on a regimen so that I would have at least 3 days off of my meds before taking ecstasy, and I was still rolling, so I continued doing this until I ran out of medication. But I wasn't seeing a doctor, and my script was out, so I was on a limited supply. I was also drinking heavily and doing lots of benzos during this period as well.
December 2008
Then I had THE comedown. I was in a relationship at the time, and she was also rolling as frequently as I was. One night, we both had the worst comedowns of our lives. I'm sure there are nuanced differences between what we experienced, but I don't think they were that different. We are still friends to this day, and whenever we think of that comedown, we both can vividly recall in great detail how horrible it was. I knew this time was different, but I still expected it to last maybe a week and half tops before I started feeling better. After the first full day after the onset of the comedown, my then-gf was so depressed and suicidal that she checked herself into a psychiatric ward. I did not have the ability to do the same for myself at the time, otherwise I'd have done the same. After the first week, my depression was worsening. I'm sure my situation -- especially the fact that my gf had left (we had been living together for almost 8 months) made this even more painful. I was so in love with her at the time, and her absence only exacerbated my despondency. I started attending AA meetings at this point because benzos and alcohol weren't doing anything to mitigate the symptoms. I would find myself crying sporadically without any reason, and I was pale and listless. I felt braindead. I couldn't think clearly, and I hardly ever spoke because I'd find that most of what I'd be saying what incoherent and jumbled -- almost like my mouth couldn't synchronize with the words I was holding in my brain.
Week 2 and I'm still not feeling any better and am growing increasingly more discouraged. Suicide had been something I had entertained previously before ever even taking MDMA, and now it was sounding more and more appealing by the second. I was also growing frustrated with considerable drop in mental acuity. I was really beginning to think I had done some serious, irreparable damage to my brain. By the latter half of the 30 days since the comedown, I get in contact with my doctor so I can get back on anti-depressants. I was abstaining from all alcohol and drugs (except caffeine and nicotine) at this point, so the meds started really helping within the week once I got on them. I was sober for almost 8 months after I had the comedown and was consistent with my medication.
June/July 2009
Then I started drinking again, then I gradually started using other drugs, but I avoided ecstasy like the plague. My depression was beginning to creep back because the alcohol and benzos (and occasional coke binge) were pretty much negating my meds. My relationship was also falling apart and even my friends who also use alcohol and drugs excessively became concerned with how much I was drinking. October 31st of 2009 was the eve of my suicide attempt. I tried slamming my car into a wall, and much to my dismay at the time, I woke up with only a minor fracture in my back. Pretty amazing in retrospect how the hell I came out of that pretty much unscathed.
Nov 2009-Jan 2010
Anyway, I was put in a psych ward after my stay in the ER. I was put on high doses of pain medication because of my injury. Opiates had never been my thing, but I had done heroin once and had maybe taken some dones a handful of times, but that's about it. I was so sick and groggy from the meds for the first week, and I was puking a lot. The only thing I could do was get up when it was time for a re-dose, and then I'd have to go straight back to my bed because the intensity of the nausea. The head doc at the psychiatric facility also put me on Cymbalta (an SSRNI) and Abilify, as well as a muscle relaxer and Trazodone. I began to actually enjoy the high of the opiates, so my stay at the unit wasn't too bad. I thought I was feeling better, but it was really just pain meds. They took me off of them as soon as I was released because they knew I was also in for chemical dependency. I get back, and even with my meds, my depression was still just as bed and I was still suicidal. At this point I start restricting my food and using laxatives because I got obsessed with losing weight. It was the only thing that motivated me to continue to exist, but I wasn't nourishing myself. Depression is getting worse, and I'm just as suicidal. I start taking amphetamines to suppress my appetite and give me some energy. I'd be intensely euphoric on them, but I was crashing hard. I couldn't get out of bed on the days I didn't take them. Started doing coke again at this point, further worsening my depression. I'm shipped off to treatment again (had been to a couple of places before then, as well as a sober living home).
Jan-March 2010
Back in treatment, back on meds, and though my depression was still very much present, it wasn't as bad. Even when sober, I still noticed that I wasn't as sharp as I used to be, and I really think it the E binge is the main reason. I also notice that I've had a very light stammer since then as well, still present but not worsening. Started drinking again within the first month (this place was an extended living program where I could go to a local community college, so relapsing was super easy because it was located in a popular drinking/party spot in Southern Cali). Still active in my eating disorder and still have the intention of killing myself imminently. My dad is refusing to pay for anymore treatment. Luckily I had some awesome people in the area who really helped me out.
Remained in Cali up until the end of May of 2012. I was in a relationship (not same aforementioned girl) and living with her at the time and was abusing Rx amphetamines heavily. I rolled one time on two tabs in October of 2011, and the subsequent comedown was the first time I had felt suicidal again in a few months. It also lasted for 3-4 days before I began feeling better. Not using meds at this point in time.
Since then, I've rolled several times with crystal/powder. Over this last summer, I took maybe 7 or 8 150 mg capsules over the course of 2 days, and my body was having involuntary spasms by the morning after the second night. Mental comedown wasn't too bad, but I think it was cut with something weird. The people who were with me on that roll were not my close friends. In fact, I'm so embarrassed about the state I was in on that second night that I would never show my face around them again. I won't make this any longer than it already is, but I had never had a *physical* reaction to a roll like that before, even though I had taken higher dosages in a shorter amount of time. I stupidly rolled again in October despite my previous roll actually scaring me, but it was from a different source whose product was very reliable and pure. No comedown besides minor fatigue and lethargy. Was just at a three day EDM festival over NYE and rolled every night. Still not feeling too bad right now, but I'm pretty sure I don't wanna do any MDMA again. I had a good time, but I know myself and where I'll end up if I continue, and rolling really isn't the same for me anymore. Fun, but it's lost its magic. I wanna end it on a moderately positive note. I had some great times with MDMA, but I cannot adequately articulate just how dark it was for me during my comedown of comedowns. Definitely the worst thing I've ever experienced.
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Some things that were developed or worsened after my first binge that are still presently affecting me:
-*Depression (pre-existing before drug use) not currently medicated, but I very rarely have fleeting thoughts of suicide and it's not as relentless as it used to be. I usually only feel down after not using alcohol, benzos, or amphetamines, which are the only things I've been using consistently other than shrooms).
-Light stammer/Saying words in sentences out of order; Diminished articulation
-Decrease in alertness and cognition
-Short-term memory loss
-Declining ability to concentrate
-Increased anxiety (pre-existing)
Please keep in mind that I know that my continued use of other substances is just as culpable in the current presence of the conditions I've listed. I have not allowed myself a full year of recovery (abstaining from hard drugs and alcohol) since my binge in 2008, but I noticed the onset of these things immediately after my worst comedown.
Anyway, I'm ready to quit using alcohol and drugs altogether. While I've been fortunate that my depression isn't nearly as bad as it was in 2008-2009, I don't want to further corrode my comprehension abilities (or lack there of) or risk catapulting myself into another seemingly inextricable cycle of depression. I know I've done damage to my brain, not just with E. But I personally believe that my abuse of MDMA was more detrimental to my mental health than my abuse of any other substance.