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A PEA version of DMT?

Oh, my mistake, sorry. There has to be away to make it less selective to the 5-HT(1B/D) receptors. Is there something which we can add or cleave to keep a similar structure but change the effects profile? This is really unlike me but the whole PEA/TYP hybrid thing has me thinking a lot lol. I'll be on this for a week! >.<
 
not really dmt related:
i remember reading here about a paper which concluded that either 4- or 5-alkylaminoindoles show stimulant activity. this was mentioned in a pretty old thread.
 

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Bottom left and right are much more of phenethylamines than tryptamines.....
 
They all look like phens, the bottom left one looks like it might be kinda mdma like. Was it 3-MeO, 4-Me amphetamine or 3-Me, 4-MeO that released monoamiines in a similar ratio to mdma? I think it was the former.
 
The top two arent distinctively phens. The ethylamino is in the wrong position.
 
I don't know that it matters where it's joined onto the benzene- I think it matters more in relation to where the chains are located. The bottom two have the best chance of full on psychedelia- though the bottom left may hint at some entactogenic properties, I think- though I doubt it's going to be a full-blown entactogenesis
 
dorothyperkins said:
They all look like phens, the bottom left one looks like it might be kinda mdma like. Was it 3-MeO, 4-Me amphetamine or 3-Me, 4-MeO that released monoamiines in a similar ratio to mdma? I think it was the former.
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I think it was 4-methoxy-amphetamine, but I can't recall with certainty.
 
PMA feels kinda like MDMA but nichols made one that was supposed to be similar in monoamine releasing properties to mdma.
 
could someone tell me the orientation of phenethylamines in the receptor compared to tryptamines? a picture would help alot. another thing i noticed was indole looks like a cyclical form phenethylamine. so what would b-(n,n-dimethyl-ethylamino)-phenethylamine be like?
 
fritzy said:
References, please?
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I don't have one, but many BLers have made this claim in various threads. I am sure you can find it in the acid/dragonfly thread. They posted links, so it does not seem to be hearsay.

ould someone tell me the orientation of phenethylamines in the receptor compared to tryptamines? a picture would help alot. another thing i noticed was indole looks like a cyclical form phenethylamine. so what would b-(n,n-dimethyl-ethylamino)-phenethylamine be like?
Click to expand...

Of course, this is all theory. New data (new to us, the compound is 10 years old) suggests this is wrong.....


tryp_phen_comp2.bmp
 
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