• Neuroscience & Pharmacology Discussion Welcome Guest
    Posting Rules Bluelight Rules
    Recent Journal Articles Chemistry Mega-Thread
    FREE Chemistry Databases! Self-Education Guide

  • N&PD Moderators: Skorpio | someguyontheinternet

A new direction for research chemicals

sekio said:
Most of the compounds released as RC's come from patents that people read, I'd imagine. Let the big pharma companies do the hard work.
Click to expand...

A1. They will uually have done quite a lot of animal work before they patent (the crude/cruel animal models back then had the one positive - cheap).

Of course, I'm sure every researcher had experienced Ratatonia.....
 
Research Chemicals are derived from one of three things. Attempt to make a legal/unregulated new or analogue chemical (MXE, Mephedrone), Trying to create safer/more enjoyable/better chemicals (rare, but originally shulgin was doing this), and research papers done by legitimate chemists and pharmacologists who are researching some other property of a novel chemical (NBOMes for example).
Click to expand...

I was talking about what has been happening after the era of legal mephedrone and legal methoxetamine. I don't suspect that the people who synthesized them first (I know that mephedrone was first synthesized in the 20th century, but then forgotten for decades) had some hidden intentions. After banning mephedrone and some of its early analogues there have been a lot of suspicious stimulants and serotonin releasers released that don't really seem to have a safe profile (e.g. toxic dose may be very close to recreational dose). Mostly it's been happening recently when most of the widely accepted RC's with few unpleasant effects had already been banned. It is inevitable that vendors one day run out of compounds that were once researched, because the RC's business evolves much faster than scientist begin conducting new researches. Either vendors start hiring researchers to make new good RC's or they simply start releasing anything structurally similar to the widely used drugs. You can't be so naive to believe that all vendors of RC's mean well for you (releasing benzodiazepines or super-potent opioids? how is this meaning well for Christ's sake and not thinking about money?), it's a business worth a lot of money after all. It's just like entertainment business, there will always be people who have a passion and love making enjoyable movies or works of art, but there will also be a lot of people who just saw an opportunity to make a good life for themselves using other people's talents (entrepreneurs or whatever you want to call them). In capitalism it pays off much more to be a born chief than to be a born inventor, but I guess I'm stepping on another topic here.
 
Last edited:
DL-ark said:
But now I wonder, has any of the chemicals thought up about on bluelight ended up on an RC Vendor's products?
Click to expand...

Methoxetamine is a famous example, it was invented by a bluelighter.
 
I prefer methoxetamine to ketamine, though it is dodgier in combinations with other serotonergics...and 3-meo-pcp might be better than the lot. . .

ebola
 
ebola? said:
I prefer methoxetamine to ketamine, though it is dodgier in combinations with other serotonergics...and 3-meo-pcp might be better than the lot. . .

ebola
Click to expand...

I've heard that the standard dose for someone using MXE is largely unknown as one of its effects is a tendency to redose... This is largely the only reason I have been hesitant to try it.
 
I also prefer MXE to Ketamine, I shouldnt have changed pofacedhoes post in my quote. I meant to say that MXE doesnt seem any more addictive than ketamine. I am going to try 3-meo-pcp again as ive had over a year to allow my tolerance to reset, I didnt find it to be to deep a year ago but perhaps a different batch and a fresh mind will provide a better experience.
 
Wanted to keep it quiet but did interviews with the press and told people on here about it....


And I can understand your concern adder, wasn't it you that posted about several novel arylcyclohexylamine compounds a few years back only for them to be on the markets within 12 months?
 
DL-ark said:
But now I wonder, has any of the chemicals thought up about on bluelight ended up on an RC Vendor's products?
Click to expand...

Dimethocaine, for sure, and I'm pretty sure mephedrone was, if not first mentioned here, from someone who was a member. Camfetamine definitely was. Pretty sure methiopropamine was too.
 
ebola? said:
Hammilton said:
Dimethocaine
Click to expand...
Hooray, go us! :P

ebola
Click to expand...
LOL!

Hammilton said:
Dimethocaine, for sure, and I'm pretty sure mephedrone was, if not first mentioned here, from someone who was a member. Camfetamine definitely was. Pretty sure methiopropamine was too.
Click to expand...
I heard claims that MXE was as well, can anyone confirm that?

Speaking of MXE - The enol tapping sounds a lot more attractive for ketamine itself in terms of availability imho. :D Only problem with that is that reaching peak plasma concentration (of ketamine) would probably take considerably longer, depending on the rate at which esterases increase hydrolysis. For me, IV ketamine is already a lot more desirable than IM ketamine, let alone insufflated doses, so it'd have to be really fucking fast.

Another problem that I could see is that the compounds would have to be carefully cleared of all remaining ketamine and if large amounts aren't stored under exclusion of water very small amounts could probably get converted back to ketamine which could then be problematic when it comes to it's legal status. While many prodrugs of illegal compounds (androgenic anabolic steroids come to mind) are still legal in some countries (the US I believe), they have easily and quickly been outlawed in others (like Germany).
 
Last edited:
Kilfer said:
In 1942? 8o
Click to expand...

Haven't you heard Bluelight is (was) the first online forum to retroactively transcend the internet?

I think he meant that RC vendors originally identified methipropamine as a potential RC candidate based on discussions in this forum, although no one but the vendors can really be sure about these things.
 
Shulgin is still the primary party responsible for recreational and medical use of MDMA, despite it having been invented in 1912. Similar circumstances surround most of...'that guy's' creations previously discussed on here.

ebola
 
You must log in or register to reply here.
Top