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a different way to name phens (or trypts)

Dresden

Bluelighter
Joined
Feb 2, 2010
Messages
3,212
What if we named pea's and amphetamines with benzene as the base of the molecule. It may very well be a better, simpler way to name. For example,

1-phenyl-2-methylaminopropane.png


So, methamphetamine becomes 1-(2-methylaminopropyl)-benzene.

1-(3,4-methylenedioxyphenyl)-2-methylaminopropane.png


MDMA becomes 1-(2-methylaminopropyl)-(3,4-methylenedioxy)-benzene.

2-aminoethyl-3,4,5-trimethoxybenzene.png


Mescaline becomes 2-aminoethyl-3,4,5-trimethoxybenzene.

2-aminoethyl-4-ethyl-2,5-dimethoxybenzene.png


2ce becomes 2-aminoethyl-4-ethyl-2,5-dimethoxybenzene.

1-(2-aminopropyl)-3,4-dichlorobenzene.png


1-(2-aminopropyl)-3,4-dichlorobenzene, etc.

I think this way is better and simpler, and opsin recognizes it just fine.
Likewise, the trypts can be named with indole as the base.
This method is just much more basic, as benzene is seen as the core of the molecule rather than some aminoethyl or 2-(methyl)aminopropyl side chain.
 
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Why? IUPAC is the common language used by chemists and has been for almost 100 years. I appreciate it can be tricky, but it's designed so no possible mix up can be made between 2 different chemicals.
 
Chemists often give their creations trivial names, which ends up being what most people call them because that is the name they are familiar with. What you are trying to do is name them systematically. But IUPAC rules already govern how to do that. However, the full IUPAC chemical name for a substance is rarely used everyday because they are unweildy, and can be difgicult to remember. It is much more compact to name DMT based on tryptamine than on indole.
 
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I tend to stick with it because chemoffice allows image<->SMILES<->IUPAC. Marvinsketch (the most useful free on-line chem software) is the Swiss Army penknife for people who don't want to invest in CO or DS.
 
To make matters more embarrassing, I think I numbered several of them wrong and hope to correct it below. It turns out, when using benzene as the basis for nomenclature of the pea's/amp's, the 2-aminoethyl, 2-methylaminopropyl, or 2-aminopropyl side chain is not necessarily #1 anymore! Also, I know alcohols are very high on the seniority list when assigning numbers, then something like 2-aminoethyl, then ethyl (for example). Not sure where the halogens necessarily fit it, but I'm going to place them before the side chain just on a whim.

MDMA: 1,2-methylenedioxy-4-(2-methylaminopropyl)-benzene.
Mescaline: 1,2,3-trimethoxy-5-(2-aminoethyl)-benzene.
2ce: 2-aminoethyl-5-ethyl-1,4-dimethoxy-benzene.
3,4-di-Cl-AMP: 4-(2-aminopropyl)-1,2-dichloro-benzene.

Idk, I just like this new system of nomenclature better than the old ones. Nomenclature is constantly evolving just like the language it is, and I think it's important to periodically come up with newer, better, simpler systems of nomenclature every so often. I mean, it wasn't long ago that amphetamines were still viewed as alpha-methyl phenyl ethyl amines instead of propane (or now, benzene) derivatives. And, like I said, OPSIN accepts all these new monikers already. As for DMT, using indole as the base really isn't hard at all:

3-(dimethylaminoethyl)-indole.png


DMT: 3-dimethylaminoethyl-indole. It really doesn't get simpler (yet) than that, guys, does it?

After all, benzene

benzene.png


and indole (Warning: Smells like flowers at low concentrations but is the chemical responsible for the odor of shit in higher concentrations!)

indole.png


and, arguably, 1,3-benzodioxole (an acidic arene whose name I didn't use above, instead opting for the interchangeable common name for that ring system--the methylenedioxy old standby name--but which can of course be used instead in the benzene-centric pea/amp system of nomenclature)

1,3-benzodioxole.png


After all, it is through these aromatic, electromagnetically active hydrocarbon ring systems, which can really be thought of as energy lenses, that give rise to the psychoactive properties of some of our best, most treasured drugs--the pea's, amp's, and trypt's. The (methyl/ethyl)aminoethyl side chains do not, in and of themselves, serve such an important function as that other than to ensure psychoactivity by making these otherwise highly hydrophobic molecules water soluble at the right, acidic pH and to of course fit the molecule to the receptor protein in the right place and with the right space between). Today, I am on methamphetamine. Can u tell?
 
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Idk, I just like this new system of nomenclature better than the old ones.

3-(dimethylaminoethyl)-indole.png


DMT: 3-dimethylaminoethyl-indole.

That is not a new nomenclature. Consulting the Merck Index, 10th Edition, p. 476, shows that DMT is also known as 3-[2-(dimethylamino)ethyl]indole. I don't think any of the names you proposed are new. There are many ways you can name compounds and all of the names you proposed have been used previously, but they fell out of favor as people adopted the more common trivial names.
 
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