• MDMA &
    Empathogenic
    Drugs

    Welcome Guest!

A bunch of E-virgin having a party, your input appreciated!

Nice to see my topic brought up!

I received my tester toward the end of last week. Luckily
we found a reliable hookup... I'll get a single dose from him
pretty soon and test it. If it comes out allright, I'll stack up
like a squirrel during fall.

The party will be held in June, around the summer solstice.
We will be able to stay outside, around a nice fire. A friend
of us has a chalet outside the city. Another possibility is to go
camping somewhere. It's still pretty much open to changes.
The most important factor is to find a suitable time for everyone,
which is not always obvious since some of us live a few hundreds of
km away.

I'll keep you posted!
 
5HTP will replace the serotonin that you will lose while rolling. Serotonin is "5HT" and 5HTP is extremely easy for your body to convert into 5HT, resulting in replenishing your brain's serotonin levels. I would suggest taking 100 mgs. of 5HTP after your roll, and another 50 mgs. later on the next day.

Something really important to remember is that you need to avoid dehydration, while at the same time you MUST maintain your body's salt balance. Drinking water alone can result in your natural salt levels being reduced (which can become dangerous if you lose too much). This condition is called hyponatremia (click on the link to read about it).

It is VERY easy to avoid hyponatremia by simply drinking liquids which are designed to maintain your electrolyte (salt) balance. Sports drinks such as Gatorade or PowerAid with keep you both hydrated, and maintain your electrolytes. There are other drinks which will do this too, just be sure to read their labels because they will state that they do this. (Don't assume that "Energy drinks" do it, because not all of them are designed this way.)

Hope you have a great time. :)
 
Thanks for the advice BrianO. I forgot to mention in my previous posts
that I bought 5HTP and multivitamins. I want to prepare a little bag
containing some vitamins and 5HTP for everyone so that they can
postload. I dunno if it is really necessary for the first time, but in any
case I'm sure the placebo effect will make everybody feel better
the next day :)
 
^^^
Something that you may want to avoid is taking any B6 either 6 hours before or before 6 hours after taking the 5-HTP.

The B6 will facilitate the 5-HTP to 5-HT conversion prematurely and the 5-HT will remain within your bloodstream (unable to pass through the blood/brain barrier). Thus negating any neurological benefits.
 
hehe, I thought I read everything there is to know :)
I'll check if there is any B6 in the multivitamins. The instructions
will be:

For the next 2 days :
Take 100mg 5-HTP
6 hours later, take vitamin

I think 5HTP is good for sleep, I wonder if it would be better
to take it before going to sleep, then the vitamin after
waking up.
 
^^^
I honestly don't know what the effect is if 5-HTP is taken while there is a substancial amount of MDMA still in your system. It may be meaningless or it may not.

Perhaps one of the other's has some information regarding this?
 
Brian Oblivion said:
^^^
Something that you may want to avoid is taking any B6 either 6 hours before or before 6 hours after taking the 5-HTP.

The B6 will facilitate the 5-HTP to 5-HT conversion prematurely and the 5-HT will remain within your bloodstream (unable to pass through the blood/brain barrier). Thus negating any neurological benefits.
Click to expand...

can you please re-word this and/or expand on the Vitamin B-6 topic a little more ???

one of the first HTP products i purchased was a combo of HTP/VC/VB6......

i pre-loaded with it and rolled balls.
last time i preloaded with 5HTP pills, and one separate VB6 pill and
rolled balls.
thanx
 
I'm not addressing the notion of pre-loading (I don't really know if there is benefit to pre-loading with 5-HTP). This is more so directed to post-loading with 5-HTP (i.e., when your serotonin stores have been depleted).

I have more medically authoritative references to this but I can't find them at the moment. Here is one for starts:
http://www.delano.com/ReferenceArticles/HTP-B6-Controversy.html

Basically, it is possible for B6 to convert the 5-HTP into serotonin before it makes it through the blood/brain barrier. Serotonin (5-HT) can not pass through the cell (neuron) body, whereas 5-HTP can (and very easily). This is also why once serotonin is stored within your neurons, it does not escape back into the blood stream.

It is possible that a surplus of vitamin B6 in the blood stream can convert the blood bound 5-HTP into 5-HT before it ever makes it's way into your brain (or better, the neurons which compose your brain). And that will prevent you from replenishing your brain's serotonin stores.

Taking B6 with 5-HTP won't prevent all of it from replenishing your serotonin stores. But it could reduce the it to a degree.
 
How bout not taking drugs to have a good time, there are other things out there you know.... not that I am a virgin in to it. But I regret every touching ecstacy..... it fucks with your motor skills and you could have an allergic reaction. I don't understand taking the risk with your one and only body.
 
Brian Oblivion said:
^^^
Let me guess. You're yet another mole working for an enforcement agency. Huh?

8(
Click to expand...

that Controversy article was an interesting read, first time i've heard of that. like i said the first 5htp product i bought came combined with the b-6 and described on the side of the bottle saying it helped the 5htp.

but lets be honest one is supposed to be taking 50mg of 5HTP a day, maybe 100mg.

i took 600mg in six hours which is abusing it. when i dropped the first 100mg i dropped 100mg of B-6 with it.

i'll keep reading up on this, thanx.
 
One thing that mixing B6 with 5-HTP will do is increase the available serotonin in the blood stream. On top of being a neurotransmitter, believe it or not, serotonin is used in the blood clotting process.

Pretty handy stuff. :D
 
From memory there was some concern about whether increased blood serotonin levels was cardiotoxic... sustained activation of 5-HT2C seems to produce fibrous heart cells which lead to heart disease...

This is the reason fenfluramine was pulled from the market...

there was a thread on bluelight about this earlier with some references, ill look later.
 
I dont know if this has been said about the whole "drinking the pill thing..." but pills are pretty nasty tasting. I dont think i could suffer through drinking enough diluted stuff to even feel the effects. PLUS if you throw up (which IS a possibility and is normal) it would be GROSS to have that much stuff in your stomach..
My advice is to swallow and wait.
Also, nack in the day when I threw roll parties *sigh so long ago* we would ALWATS have tons of frozen juicy foods. Tropicana makes an AMAZING orange/vanilla creme bar thing, and frozen blueberries are also really fun to eat. Anything not heavy, cold and wet will work. Your not gonna be hungry, but its fun to have somehting in your mouth.
 
VelocideX said:
From memory there was some concern about whether increased blood serotonin levels was cardiotoxic... sustained activation of 5-HT2C seems to produce fibrous heart cells which lead to heart disease...

This is the reason fenfluramine was pulled from the market...

there was a thread on bluelight about this earlier with some references, ill look later.
Click to expand...
I remember reading that as well. If I remember correctly, that only occurred when 5-HTP was injected directly into the cardiac muscle.
 
I just want to tell you that your friends will LOVE you when you give them some postloaders when they leave the party. We had a party at our house one night and I had those snack-sized Ziplock bags. I put some 5htp and some St. Johns Wart in them...enough to last for a few days and gave it to them on their way out, explained how they should take it and they gave me a big hug and acted as if I just gave them a bag of money. :)
 
I personally think that 5-HTP isn't MUCH of a concern for cardiac tissue due to platelet MAO... MAO in the bloodstream keeps levels of catecholamines at a reasonable level (probably why they're there?), and I can't see why they wouldn't be able to deal with a little excess....

I'd be more concerned about such problems with MAO inhibitors, but then again there was an article that I saw recently saying the benefits provided outweighed the risk in that depression is a significant risk factor for heart disease anyway.

unicorngoddess - st john's wort has both reuptake inhibiting and mao inhibiting properties and so I cannot recommend its concurrent use with 5-HTP... there is a non-negligibile risk of serotonin syndrome occurring.
 
Zoloft is an antidepressant and shouldn't be taken before MDMA. In the case of Zoloft specifically it does not cover the same range of receptors that MDMA does so you can get an effect from MDMA while on Zoloft but don't bother risking a dulled experience.
 
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