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6APB, Vasoconstriction, NEED ADVICE

idontdothizz

idontdothizz

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Joined
Jun 21, 2009
Messages
185
So almost a week ago I tried 6-APB for the first time, 145mg. I had a very bad comedown, but the most concerning thing was vasoconstriction. That was the most uncomfortable and annoying thing and lasted for 10 hours. During this time I did some research and got some l-arginine.

I tried 6-apb again but this time loaded up on l-arginine. This time I did 80mg. Great peak and for the peak I had almost no signs of vasoconstriction. But after I started coming down is when it started and it kept getting worse no matter what I did. The l-arginine stopped working. It's like my heart was working too long and could not take it anymore. The vasoconstriction is terrible, feels like my heart is going through too much work, my eyes feel very tired, when I stand up i feel like I am going to pass out.

So now I have another theory. Since l-arginine works for the peak effects and it's the comedown that fucks with me, could I get through this by ordering some etizolam pellets(benzo analog)?

Please give your opinions. Warm baths and massages do not help.
 
Sad to hear that, most people find 6-APB very light on the body, instead it can be a bit hard on the mind - I'm going to repeat Renz Envys, aren't you anxious? Heart problems are magnified by 1000x by anxiety, maybe you're perfectly well physically and just think your heart is working hard since you're uncomfortable.
 
Benzo's help a lot for me regarding vasoconstriction or to be more precise: residual stimulation. It's relatively normal for stimulation to start more pleasantly and centrally acting, then on the comedown turning more and more peripheral i.e. (uncomfortable) side-effect like.
Sorry to hear you experience the residual stimulation so badly, I recommend that you lower your dose for next time and then if the tension is still too much when you come down take etizolam. Try the etizolam by itself first so that you know how you react to a certain dose.
Combining uppers and downers is generally not a good idea but it beats having to endure harsh stim comedowns. Be prepared to feel a little weird and fluttery in your chest: the stronger the stimulation is when you take a downer the more confused your body gets, getting mixed signals. Typically the effects average out regarding HR and BP (I think) but it's probably not stable for your body. So keep all of that to a minimum.

Last time I had a messed up comedown with terrible residual stimulation I was on opium which is unfortunate since I didn't think it safe to try and calm down with benzo's. I ate a 1 mg xanax pill over the course of many hours. A tiny crumb at a time to avoid any danger. I absolutely hate and fear respiratory depression.

I only received etizolam pellets (I say just call them pills ffs ;) ) yesterday, but I am interested to find out how it compares to benzo's.
 
Yes i do experience pretty shitty anxiety... i noticed when I am peaking I am breathing pretty weird. as I inhale my heartrate slows down significantly, and then as I exhale it speeds up. sound familiar to anyone? It really sucks because the roll this stuff gives you is just sooooo good..
 
Yes I know the breathing problems and I hate it. Related to hyperventilation... rapid cycling of heartrate doesn't ring a bell though, are you sure it doesn't just feel like that?
 
^FWIW, I haven't tried 6-APB but etizolam is about equally effective for stimulant comedowns as alprazolam/Xanax is (IME). My stimulant of choice is dextroamphetamine, hwoever, not 6-APB.

Solipsis makes a great point, using benzos and other downers for stimulant comesdowns isn't something you want to make a habit of, but its better than just dealing with a horrible stimulant comedown (I've been there).
 
If you're gonna give advice like that, mention to take them one at a time instead of 4 under your tongue. No need to go overboard, enough is enough.
 
Although this is off-topic, you said you took 6-APB a week ago and took it again this week? Of course you're going to have a rough comedown. Like MDMA/MDA etc, 6-APB is likely to be a powerful serotonin releaser, as the effects suggest - as such, like with these drugs, using it will cause serotonin down-regulation.

It takes a while for your serotonin transporters to regulate back up again with MDMA, somewhere around a month, more for some people - and so taking one of these drugs more than once a month is likely doing yourself some serious damage. This is especially true for something like 6-APB where there are no studies so for all we know it could be far worse in this respect than MDMA or MDA. Severely depleted serotonin transporter concentrations in the brain can result in: A reduced experience with 6-APB, MDMA, MDA, and other serotonergics - also known as the "loss of magic" because that once magical feeling is now gone, much harsher and more depressing comedowns, anxiety and depression in daily life when sober, mood swings, etc.

Please space your experiences out by a minimum of a month.

Back to your issue, Etizolam certainly could help for the comedowns, but I think the most important thing is to decrease your frequency of use, make sure you're hydrated and healthy during your rolls, and avoid dosing too high or redosing.

Also, while it does not help the comedown itself, I've found eating cheese and other food high in tryptophan seems to help with the hangover afterwards. I seem to remember reading some studies suggesting that tryptophan-rich foods might actually be more effective in increasing brain serotonin levels and combating depression/anxiety than 5-HTP, which is commonly supplemented to battle these hangovers - however don't take my word for it as I'm running on little sleep and can't back that up right now.

As for vasoconstriction, my tried and tested home-remedy is a small amount of weed and a cup of tea. :)
 
The thing is, Jesusgreen. The comedown was a whole lot easier. All except for one thing, my heart. I had no headache the next day, no depression the next day... The first time I did it, I had a huge headache and severe mood swings. This time, the only bad thing other than vasoconstriction, was that I was a little tired the next day.
A couple years ago I had an overdose on ecstasy(or whatever it was) during this time I had a severe hypertensive crisis, to the point where I experienced rhabdomyolysis. I fully recovered with no problems except now when I take stimulants I am a little bit more susceptible to heart problems than others. I think it may be anxiety related, it makes a lot of sense.
 
Well of course, since you dosed far lower you were able to avoid the likely very severe comedown that would have accompanied dosing so soon after your last roll.

Anxiety is definitely like to be to blame for most of this. As for the vasoconstriction you didn't really specify much in the way of symptoms, the symptoms you listed sound in line with sudden changes in blood pressure, or too high/too low blood pressure - high blood pressure is definitely likely with something like this, especially if you've had problems in the past.

With vasoconstriction the main thing you need to look out for is your knees, elbows, knuckles etc turning a purple-red, generally - the more purple the worse the vasoconstriction. Some vasoconstriction is normal with stimulants, its if it gets bad that you should be concerned.

Along with weed and tea, magnesium can act as a vasodilator to help counter-act vasoconstriction - and magnesium is a life-saver here as it also helps ease muscle tension, including the annoying eye rolling and jaw grinding that 6-APB can cause. Just take the recommended daily amount and no higher, and it should help.
 
hmm okay symptoms...
extremely uncomfortable tingling sensations in hands, feet, and face.
weird prickley/stinging sensations at random parts of body.
hates to stand up because it feels like all the blood is rushing, like my face will get 5 times more tingly for a few seconds and I will be light headed.
I thought it was vasoconstriction but im starting to think it is something else, because after taking enough l-arginine, and eating some food and taking a multivitamin, my veins got thick again, but I was still having the numbing sensations.
I just want to make sure nothing permanent/bad can happen for feeling like this too long
 
sounds like low blood pressure to me. or maybe anxiety/hyperventilation (the standing up part doesn't fit here). have you tried lying down on the floor and putting your feet up on a chair or something?
 
hmm okay first of all I greatly appreciate you guys trying to help me.
Second, the reason I think it is low blood pressure is because of how shitty it is if I stand up. I get light headed and my face goes very prickley,tingly,numb. Also, when my veins get bigger again after the stimulant is finally starting to wear off after hours and hours, I still feel tingly in my fingers and still get a bit light headed when I stand.

And I do have anxiety which is probably why it gets so bad
 
idontdothizz said:
hmm okay symptoms...
extremely uncomfortable tingling sensations in hands, feet, and face.
weird prickley/stinging sensations at random parts of body.
hates to stand up because it feels like all the blood is rushing, like my face will get 5 times more tingly for a few seconds and I will be light headed.
I thought it was vasoconstriction but im starting to think it is something else, because after taking enough l-arginine, and eating some food and taking a multivitamin, my veins got thick again, but I was still having the numbing sensations.
I just want to make sure nothing permanent/bad can happen for feeling like this too long
Click to expand...

Just wanted to mention, I had effects very similar to this during the comedown of my last time on methylone. Typically I do great with methylone, but I think I overdid it a bit this time. (170mg initial dose followed by 100mg about 1.5hrs later).

Any other insight on what exactly we were feeling? Certainly I became a bit anxious over it, but I don't think that was the primary issue. I was thinking it might be related to the build-up of metabolites. What I'd really like to find out is to what degree effects like these can be considered dangerous should I ever find myself or someone else experiencing them in the future.
 
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