6-APB induced neurotoxicity?

addar

Greenlighter
Joined
Jun 12, 2011
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37
I have been in some kind of panic state for 2 weeks since my last research on 6-APB. I won't go into much detail but you can read it here if you wish to.

So 4 weeks of research (only weekends- friday and sat nights) on 6-APB, at doses ranging from 1 to 3 official batch 8 pellets, gave me a huge physical and mental crash at the end of 4th weekend. I have been recovering steadily since then, been 15 days, but i am stuck with a residual stimulation that i am afraid will not leave me. It's hard to sleep without benzos, i have muscle twitches all over my body, though not serious, my chin is sligtly quivering, theres a feeling of unease which gives me urge to do movements like stretching my fingers etc. I feel like an electric current is travelling thru my muscles and excite them. My limbs feel weak and theirs a feeling my muscles are melting slowly. I like to retain muscle mass and i think i lost a good chunk in the process.

I am scared to shit that 6-APB induced neurotoxicity might have caused some kind of neuromotor impairment. Will this feeling of electrical unease ever leave my body ?
 
Hi addar, you have parttaken in a reasonable level of abuse of 6-APB so it's understandable that you're suffering some lingering side effects. The good news is that whatever damage you have done is NOT permanent. You will eventually return to your normal state. How long it will take is difficult to say, not only because this substance isn't very common so we don't have much anecdotal evidence, but also because there are always individual differences in recovery time when it comes to psychedelics abuse.

The most important thing you must adher to is no more psychoactive substances for a good long while. You need to give your brain a chance to recover.

You can also speed up the recovery process by living a healthy lifestyle. Eat lots of fresh fruit and vegies and a good source of protein every day. Drink plenty of water, at least 2 litres/half a gallon every day. Exercise is also really important as it releases endorphins which act as natural mood-stabilisers. So try to get in some moderate exercise at least 3 times a week. If you take good care of yourself you should begin to notice your symptoms subsiding.

However if you are really struggling please don't hesitate to seek medical assistance.

Let us know how you're going okay? Take care <3
 
Thanks for the reply n3o. Good news is i laid off ritalin since yesterday and twitches / fasciculations almost subsided.

Bad news is i was on treadmill yesterday and got dizzy walking at 3 mph and experienced palpitations. It came quite as a shock because i could last an intense cardio session 2 months ago wherre i burnt 600-700 kcals. Even though i think its more related to panic than a heart condition, it didn't feel nice to have an aerobic capacity of some mid 60s with 90% arteries blocked.

Yeah i know the road to recovery is a little demanding but i am determined to get back to where i was 2 months ago. I even flushed the amT and 5 pellets of benzo fury that i don't remember when i ordered down the toilet.

Do you think it would help me to be on beta blockers for some time ?
 
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6-APB effected me in a similar way, i did 200mg all in 4 hours and it left me with a 'popping' sound inside my head where i think the seratonin receptors are located. Probably gave me a bit of brain damage, not trying that substance again, its way to powerful! Its been a couple of weeks since then and i feel much better. I'd say just have some vitamins.. eat lots of fruit and it will eventually go away.
 
Thanks for the reply n3o. Good news is i laid off ritalin since yesterday and twitches / fasciculations almost subsided.

This is great, nice one addar! :)

Bad news is i was on treadmill yesterday and got dizzy walking at 3 mph and experienced palpitations. It came quite as a shock because i could last an intense cardio session 2 months ago wherre i burnt 600-700 kcals. Even though i think its more related to panic than a heart condition, it didn't feel nice to have an aerobic capacity of some mid 60s with 90% arteries blocked.

Like you know, taking things easy, just for the time being, seems to be what your body needs for now.

Yeah i know the road to recovery is a little demanding but i am determined to get back to where i was 2 months ago. I even flushed the amT and 5 pellets of benzo fury that i don't remember when i ordered down the toilet.

Love this fighting talk, fair play to you that you actually, actively doing what you need to do to help yourself. These things take time to heal over but youl get there. keep us posted.

Do you think it would help me to be on beta blockers for some time ?

Cant answer this am afraid. Beta Blockers can have side effects too. I would imagine that it would be better to just bear things out and witness your bodys natural responses toward improvement but cannot say for sure.
Maybe its best to consult your Doc for this?
 
I feel obliged to warn people like me who try to lead an otherwise healthy life except a week or two madness every 6 months.

STEER AWAY FROM 6-APB.

The buzz is good, intense euphoria is there so it's worth the money, but definitely NOT worth the consequences. Made me regret big time, will most likely make you regret as well. My left biceps, which was 2x bigger 2 months ago, is twitching and there's a feeling of exhaustion on my calves as i am writing this. NOT A GOOD SIGN.

It's just a shame i did this to my body.
 
Not yet mate. I'll take a good rest at the weekend. then on monday head to gym. If i reckon i am not as capable physically, i'll see a doc.
 
The best description of the my current state would perhaps be the one you get after t+4 during a medium strong amT buzz, thats when you want to sit down because you feel heavier, muscles are easily exhausted and theres the general uneasy feeling besides the beautiful euphoria and happiness :D

Meh i don't want to whine any more, online diagnosis is not possible, plus whats happened happened and its my fault so i have to live with it. See ya after work out on monday, lets hope i still keep the coordination, balance etc, its easy to replace the lost mass after all xD
 
thanks for the warning in advance, addar. A newer Bluelight thread out there got people into mumbling about trying 6-APB! Seems like there's work to do, going out there warning all those other people about 6-APB's dangers...

Hope you get well son, addar, and keep us updated about how you're doing.

A new thread on bluelight got people onto 6-apb? TBH, you seem entirely uninformed and making snap judgments based on the sole experience of one poster who has abused 6-apb.

1) if anything got people to try 6-apb, it was the huge offsite hype in the vending world and the lower redose compulsion, longer duration and seemingly benign physical effects. Not a single trip report on bluelight, the creator of which you are unfairly beleaguering.

2) As far as I know no pharmacological data suggests that 6-apb is particularly dangerous if taken reasonable. One experience from someone who overdid 6-apb is not reliable, clinical evidence of its danger. If you want to back up your claim, maybe ask on ADD if there are significant neurotoxic properties of 6-apb, but until then I'm really not fond of someone making a witch hunt out of a reasonable research chemical.
 
Let's hope people don't do things they will regret.

After 3,5 weeks i am almost recovered except some minor tremors, "shaking" muscles when contracted and like 10 lbs of lean mass :P

IMme90; what do you mean with "longer duration" ? Seems you never researched the compound ;)

Besides i am not making a witch hunt, just giving a heads up to people who have a healthy diet, exercise regularly and like to stay fit.

For those who have their own path to walk, i don't have anything to say.
 
Let's hope people don't do things they will regret.

After 3,5 weeks i am almost recovered except some minor tremors, "shaking" muscles when contracted and like 10 lbs of lean mass :P

IMme90; what do you mean with "longer duration" ? Seems you never researched the compound ;)

Besides i am not making a witch hunt, just giving a heads up to people who have a healthy diet, exercise regularly and like to stay fit.

For those who have their own path to walk, i don't have anything to say.

In fact, I have never taken 6-apb. That does not mean I'm not qualified to say that one individual experience from someone who took an extremely high 6-apb dose several times is not indicative that 6-apb is neurotoxic, especially in the face of many, many reports from people who have taken 6-apb with no harm.

As for the witchhunt, I was referring to Wonkamonk, who decided to post in someone's TR about 6-apb about this supposed danger concerning 6-apb and then made the outlandish claim that somehow this TR was responsible for everyone trying 6-apb.

edit: the longer duration was referring to its duration compared to other research chemical alternatives to MDMA such as 4-MMC and bk-MDMA.
 
Do you consider 3 pellets extremely high dose ?

6 hour must be the longest drug binge you have ever heard of!
 
Well, if we're talking 300mg, that is a pretty high dose, especially to take twice a week. Maybe not "extremely," but "higher than normal," sure. Look, I don't have a problem with a warning, and my post wasn't ever directed at you, so don't sweat it too much.
 
If we agree on that 300 mg is a high dose, what's wrong with me warning people to limit their research to a single pellet?
 
Nothing - I just told you my post was never directed at you. *sigh* I just said I have no problem with a warning. Like I said... don't sweat it I just don't want Wonkamonk going around telling everyone not to take 6-apb and castigating people for making TRs...
 
Hey, I am not actually saying that only one post out there is giving people a good opinion about 6-APB, nor did I say that such a post is making people do this stuff. In fact, there are too many posts out there about positive experiences regarding 6-APB to actually carry out the so-called 'witch hunt' successfully, although trying to warn others should prove better than keeping my mouth shut, eh?

The thing here is, before doing a drug, the said person who wants to do the drug should be able to make a reliable cost/benifit analysis; it is only then when a person can do a drug responsibly. As for research chemicals, there is one thing that is inacceptably waaay too lacking: the cost part of the equation. The benefit is always the same thing, which is roughly about feeling good; otherwise, the said 'drug' wouldn't be in the scene anyways in this case. The cost part of the whole thing is the risks, dangers, or any other factors that may have a negative impact on you. When this is not known, then you actually don't know what are the 'so-called' dangers (common sense); this translates to irresponsible drug use, whether you like it or not, unless you happened to sign a contract that you are doing the substance at your own terms (aka all blame lies on you). Moreover, negative effects tend to be combatted by the medical profession more efficiently than less known ones.

For example, the effects of MDMA, both good and bad, that is, are well known. The positive effects are feeling great euphoria, greater capacity in interacting with others, and a greater capacity of empathy (among other things), all experienced as the drug circul;ates in your body. The negative effects include possible malignant hyperthermia, bruxism and serotonin syndrome (this in certain combinations) in the short term; as of the long term, effects include failing memory and neurotoxicity (some of which is permament). Many people may be able to cope with many of the mentioned negative effects; many others may not, and yet others may claim to be able to cope, or they may merely take their chances, when in fact they cannot deal with at least the expected drwbacks that may come to reality. But the cost/benefit factors are clear-cut and crystal clear; at least you know what you're dealing with. Here, you can make a choice on something that is very reliable; now, all reliability depends on your resultant choice.

Sometimes, a certain 'bad' effect a drug may bring on will not affect all user populations of the drug, and perhaps not in a readily manifest way. For example, psychosis that is triggered by LSD usage only occurs with those with certain prepositions for any of the psychoses, while methylphenidate psychosis occurs unpredictably but not with all methylphenidate users and more consistenty with those who used it in their childhood or adolescence.

Moreover, you cannot deny that what happened with addar and valae cannot be denied of their existence and have revealed themselves sometime after they started using 6-APB. If you ask me, their present condition, well, could be linked to their 6-APB usage. Honestly, it's good that he even cared to warn you in advance of such a thing were it to happen to you (I hope not, though).

However, all recreational drugs do not hold a zero cost profile - and the higher the high, the worse the risks tend to get. The goal here is to at least know what you're dealing with, what to do before and while high and to know what to do in worse-case scenarios. This is especially true with psychedelics, where set and setting and dosage make a possibly huge difference in subjective effects.Lowering dose and frequency tends to not only help prevent development of tolerance/dependence but also helps making the 'cost' aspect of the drug more acceptable/tolerable.

In the end, it's your choice in the end. If you want me to mind my business, then, as I see it, you're on the wrong forum. Remember, this is a harm reduction forum, right? I hope you make use of the above guidelines, or at least give me some meaningful feedback. I'm here to help, not to get a headache. I know this is a very long post, but I hope you guys find it meaningful too.

what are u doing here? I thought you were still grappling with a debilitating wort addiction....
 
Hey, I am not actually saying that only one post out there is giving people a good opinion about 6-APB, nor did I say that such a post is making people do this stuff. In fact, there are too many posts out there about positive experiences regarding 6-APB to actually carry out the so-called 'witch hunt' successfully, although trying to warn others should prove better than keeping my mouth shut, eh?

The thing here is, before doing a drug, the said person who wants to do the drug should be able to make a reliable cost/benifit analysis; it is only then when a person can do a drug responsibly. As for research chemicals, there is one thing that is inacceptably waaay too lacking: the cost part of the equation. The benefit is always the same thing, which is roughly about feeling good; otherwise, the said 'drug' wouldn't be in the scene anyways in this case. The cost part of the whole thing is the risks, dangers, or any other factors that may have a negative impact on you. When this is not known, then you actually don't know what are the 'so-called' dangers (common sense); this translates to irresponsible drug use, whether you like it or not, unless you happened to sign a contract that you are doing the substance at your own terms (aka all blame lies on you). Moreover, negative effects tend to be combatted by the medical profession more efficiently than less known ones.

For example, the effects of MDMA, both good and bad, that is, are well known. The positive effects are feeling great euphoria, greater capacity in interacting with others, and a greater capacity of empathy (among other things), all experienced as the drug circul;ates in your body. The negative effects include possible malignant hyperthermia, bruxism and serotonin syndrome (this in certain combinations) in the short term; as of the long term, effects include failing memory and neurotoxicity (some of which is permament). Many people may be able to cope with many of the mentioned negative effects; many others may not, and yet others may claim to be able to cope, or they may merely take their chances, when in fact they cannot deal with at least the expected drwbacks that may come to reality. But the cost/benefit factors are clear-cut and crystal clear; at least you know what you're dealing with. Here, you can make a choice on something that is very reliable; now, all reliability depends on your resultant choice.

Sometimes, a certain 'bad' effect a drug may bring on will not affect all user populations of the drug, and perhaps not in a readily manifest way. For example, psychosis that is triggered by LSD usage only occurs with those with certain prepositions for any of the psychoses, while methylphenidate psychosis occurs unpredictably but not with all methylphenidate users and more consistenty with those who used it in their childhood or adolescence.

Moreover, you cannot deny that what happened with addar and valae cannot be denied of their existence and have revealed themselves sometime after they started using 6-APB. If you ask me, their present condition, well, could be linked to their 6-APB usage. Honestly, it's good that he even cared to warn you in advance of such a thing were it to happen to you (I hope not, though).

However, all recreational drugs do not hold a zero cost profile - and the higher the high, the worse the risks tend to get. The goal here is to at least know what you're dealing with, what to do before and while high and to know what to do in worse-case scenarios. This is especially true with psychedelics, where set and setting and dosage make a possibly huge difference in subjective effects.Lowering dose and frequency tends to not only help prevent development of tolerance/dependence but also helps making the 'cost' aspect of the drug more acceptable/tolerable.

In the end, it's your choice in the end. If you want me to mind my business, then, as I see it, you're on the wrong forum. Remember, this is a harm reduction forum, right? I hope you make use of the above guidelines, or at least give me some meaningful feedback. I'm here to help, not to get a headache. I know this is a very long post, but I hope you guys find it meaningful too.

I did find this a meaningful post, and to be honest, if this is what you had written to begin with, I would have had no qualms. :) The tone of your original post seemed just a tad caustic and overly definitive when it came to the apparent "harm" of 6-apb which I wasn't fond of, especially since it was in the TR forum, which, while of course about harm reduction, is also about document peoples' experiences, which shouldn't be discouraged. But, you've made your point now and I don't disagree. Peace all
 
Nothing - I just told you my post was never directed at you. *sigh* I just said I have no problem with a warning. Like I said... don't sweat it I just don't want Wonkamonk going around telling everyone not to take 6-apb and castigating people for making TRs...

It's amusing how people are avoiding to find any fault with this substance. Almost as if they have formed kind of emotional bond with it. The people who accuse me of being irresponible with this chemical... They have a point. Though in my day, the amount of irresponsibility i displayed with illegal ones would match that of a mother who threw an infant to trash can! Never felt toxic this way, my worst come down with speed would feel like a mild headache compared to this one.

To the folks who don't want me to say anything bad on 6-APB.. I am merely passing information on this chemical to you without any strings attached. What you do with it is your own problem.

Now that the burden of warning people is lifted off my shoulders, i don't really care about the rest.


@@ ImMe this isn't a reply to any specific post of yours but a general take on peoples' approach to the matter.
 
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