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5ht1a vs 5ht2a

electrodevo said:
5-MEO-MIPT is known to have an "opening up" quality like MDMA, and (though the Ki values here don't indicate so) I've read that one theory behind MDMA "magic" is oxytocin release via 5-HT1A agonism. Hmm.
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Yep, and the advantage of 5-meo-mipt is that it doesn't deplete your serotonin reserves like MDMA does, so there's no bad comedown.

5-meo-dmt is an even more selective 5-ht1a-agonist, and on a small vaporized dose i thought to myself: "That's what MDMA WANTS but FAILS to be."
Enormous peace, but without feeling as "forced" as MDMA does, and with no bad comedown.
But the dosage if VERY important w/ 5-meo-dmt, if you take too much it can be very traumatizing.
Both my best and my worst trips have been on 5-meo-dmt.
 
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