5-ethyl-5-dichlorotrifluoroethylene-barbiturate

[thesomoan]

So this is the first time i've ever tried doing this so if and most likely when Im wrong I'd love some feedback, but shouldn't 5-ethyl-5-dichlorotrifluoroethylene-barbiturate be an active barbiturate. I read an article (citation below) saying that fluorinated barbiturates are among the most active, although as you can see the article is over fifty years old so idk.





Barbituric Acids1


First PageHi-Res PDF[368 KB]
William F. Bruce, Richard deV. Huber
J. Am. Chem. Soc., 1953, 75 (19), pp 4668–4670
DOI: 10.1021/ja01115a014
Publication Date: October 1953

edit: there would be a double bond between the carbons in the diclorotrifluoroethylene

 

[Hammilton]

why don't you give us some IUPAC to go with.

all of these articles are going to be quite old.

 

[atara]

That's too many substituents on an ethylene.

 

[Hammilton]

I assume he's talking about 5-(1,1-dichloro-2,2,2-trifluoroethyl)-5-ethylpyrimidine-2,4,6(1H,3H,5H)-trione

 

[dread]

edit: there would be a double bond between the carbons in the diclorotrifluoroethylene

This is wrong on so many levels. Well, actually just one: it's impossible.

 

[StaySedated]

where the hell would you find this bizarre barbiturate? i highly doubt its available online, and i'm sure this was never a Rx'ed barb.

"common" barbs are rare enough these days, why look into this? i'm sure secobarbital or phentobarbital would actually be easier to find, and they're as recreational as can be.