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  • BDD Moderators: Keif’ Richards

5,400mg of Ibuprofen?

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Flo-Rida

Bluelighter
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Jul 31, 2009
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What are the potential health concerns if a person takes 5,400mg of Ibuprofen at one time? And don't say death, because this person certainly isn't dead.
 
http://en.wikipedia.org/wiki/Ibuprofen#Overdose

edit: according to their severe dosing amount, you're pretty much there. I'd go to the hospital, you're not going to notice until it's too late like said above.

nvm 30g is their severe dose, I mathed wrong.
You're probably ok with regard to serious health problems
 
Last edited:
Stomach ulcers, bleeding, potential colitis, liver damage and kidney failure with long term abuse. If the person who took it isn't having stomach pain or cramping, and isn't passing blood in their stool or vomit; if they are asymptomatic for a few days, they are likely fine.

Taken from wiki:
Ibuprofen overdose has become common since it was licensed for over the counter use. Many overdose experiences are reported in the medical literature, although the frequency of life-threatening complications from ibuprofen overdose is low. Human response in cases of overdose ranges from absence of symptoms to fatal outcome in spite of intensive care treatment. Most symptoms are an excess of the pharmacological action of ibuprofen and include abdominal pain, nausea, vomiting, drowsiness, dizziness, headache, tinnitus, and nystagmus. Rarely, more severe symptoms, such as gastrointestinal bleeding, seizures, metabolic acidosis, hyperkalaemia, hypotension, bradycardia, tachycardia, atrial fibrillation, coma, hepatic dysfunction, acute renal failure, cyanosis, respiratory depression, and cardiac arrest have been reported. The severity of symptoms varies with the ingested dose and the time elapsed; however, individual sensitivity also plays an important role. Generally, the symptoms observed with an overdose of ibuprofen are similar to the symptoms caused by overdoses of other NSAIDs.
Correlation between severity of symptoms and measured ibuprofen plasma levels is weak. Toxic effects are unlikely at doses below 100 mg/kg, but can be severe above 400 mg/kg (around 150 tablets of 200 mg units for an average man); however, large doses do not indicate the clinical course is likely to be lethal. It is not possible to determine a precise lethal dose, as this may vary with age, weight, and concomitant diseases of the individual patient.


Suffice to say, taking too much is not a good idea. Toxicity is variable to the point of unpredictability, and long term abuse will most certainly cause serious health problems.
 
Well the stomach pain was there, but went away over night. Now there's nothing.
 
Ibuprofen is a non steroidal anti inflammatory drug (NSAID). Recommended daily max is 1200mgs or rarely 3600mgs under medical supervision, so this is definitely considered an overdose.

Ibuprofen damages the lining of the stomach, which can allow the acidic gastric juices to damage the wall. This can cause bleeding and even perforation in some cases. It is also an antiplatelet drug and increases your risk of haemorrhage. It is also nephrotoxic (damages the kidneys). The risk of kidney damage is increased if you are dehydrated or taking other nephrotoxic drugs. The kidney damage can be permanent if it is not treated.

It can also rarely cause an irregular heart beat, tinnitus, headache, vomiting and seizures.

As this is an overdose your friend needs to get to hospital ASAP. They will need blood tests to investigate their kidney function and to see if they have been bleeding internally. Ibuprofen overdoses can cause permanent damage to your kidneys, or internal haemorrhaging. You may not notice any symotoms, especially with then kidney damage, so don't assume things are fine because you feel okay..

I am going to close this as you need to get to the hospital ASAP. Good luck <3
 
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