A friend of mine got his hands on another research chemical (RC) in the stimulant class, 4F-MPH.
This was of interest, because he wanted something that relieved chronic fatigue, provided physical energy and better mental focus. Having tried other RC stimulants and finding them too pleasurable to be used as functional stimulants decided to try 4F-MPH as many reports seemed to indicate it is not pleasurable or euphoric at all, and definitely closer to a medical substance like Adderall etc so more suitable as a work or study aid.
Appearance and characteristics:
Fine white powder, looks very similar to pure cocaine. No smell. Mildly bitter taste. Quite a caustic substance (burns tongue if dissolved in mouth) and if insufflated there is a mild burn, but not too bad due to the very small amounts needed (5-10mg).
4F-MPH is extremely potent and normal dosage is in the range 5-20mg, with 20mg considered a moderate-to-high dose and probably 5-10mg a normal dose. My friend started with a 5mg test dose (insufflated) and found this fairly stimulating and felt more awake, slight mood lift, but nothing remotely pleasurable or euphoric. Basically similar to caffeine, but with a much slower onset (about 30 mins) and a much longer duration of action (about 7-8 hours taken once, 10-14+ hours with 1 re-dose). Higher doses were tried, from 10mg to 30mg, and these only increased the amount of stimulation (and negative side effects), taking the dose higher did not provide any euphoria or anything of recreational value. Even pushing the dose to 100mg in a single day (4 doses spread apart by 3-4 hours) - NOTE this is not advisable and could be dangerous and it did not provide anything remotely close to recreational or pleasurable and only amplified the principle effects of feeling more awake, alert and stimulated into a more uncomfortable zone.
There are no compulsive urges or cravings to re-dose with 4F-MPH like there can be with other RC stimulants. Re-dosing (particularly beyond midday) seems to be wasteful, certainly beyond 1 small re-dose. Sleep became impossible on 4F-MPH with repeated redosing into the afternoon and early evening. Even with the use of benzodiazaphine drugs taken at double a normal knock-out dose, so this gives an idea of the potency and how this substance is very 'cognitive' and very similar to Modafinil in effect (which my friend has tried).
Summary of effects (positive):
- A rather slow onset (30-40 minutes or longer orally) which makes abuse or re-dosing unlikely.
- A more awake state, physical energy and stimulation very similar to caffeine or a pharma drug like Adderall, Modafinil etc.
- Only a fairly small dose needed (10-20mg) once a day in morning, repeated re-dosing only increases the side-effects and duration.
- A very functional stimulant with a very long duration of action (7-8 hours) and no urge to re-dose or abuse.
- A very clear headspace, mind is very focused on whatever task you're doing, no craving for chat or sensory stimulation.
- A mood boost (from increased dopamine) but this is subtle and more like an anti-depressant, rather a coke or amphetamine rush.
- No comedown, quite tolerable to use repeatedly for many days in a row at normal dose range without any ill effects.
Summary of effects (negative):
- Long duration of action, with a long residual physical stimulated feeling which can be unpleasant and make sleep difficult.
- The stimulation feels a little 'forced' particularly at higher doses and can lead to feeling jittery/nervousness or anxiety.
- Affects waking sleep cycle dramatically, especially if taken beyond midday making sleep impossible.
- Substance seems quite caustic (supported by other reports) and can cause mild tissue damage to nasal passages and mouth, plus gastric disturbances.
- Higher doses and/or repeated re-dosing can lead to muscular and cardiovascular tension.
Summary of effects (neutral):
- Appetite suppression, not major though.
- Increased heart rate and blood pressure, again nothing major.
- Flushed face at higher doses, particularly if combined with alcohol.
Any questions, please feel free to ask. My friend has been using this substance now for 2 weeks almost daily at varying doses and has a good feel for the drug and its effects compared to both other RC stimulants (he's tried many so can make comparisons) and also Modafinil and other similar prescription 'smart' drugs, which he has also tried. He says he prefers 4F-MPH over Modafinil and Adderall, as it's not quite as physically stimulating (except at higher doses, i.e. 30+ mg) or prone to causing anxiety as those drugs usually do for him at lower doses relative to 4F-MPH for basically the same level of cognitive and energy boost benefits. As an aside note, seen reports of people also commenting that 4F-MPH may have an anti-depressant use potential, as it lower doses it does seem to act like an anti-depressant acting on dopamine though rather than serotonin, according to the limited scientific info available.
Safety, toxicity & health risks
Finally, please remember as with any RC drugs these effects may be subjective and your experience may be different so start slow with low doses and be careful. Remember this is fairly untested substance in humans, with no clinical trials and a fairly limited history of use in human subjects. The risks and toxicity side of things, particularly longer-term are unknown same as with most RC's, but for short-term and occasional use it seems quite safe. With its potency and a steep dosage-to-effect profile, caution is advised on people with health or heart problems and probably unwise mixing it with other stimulants or drugs, including alcohol beyond light use.
We haven't seen any reports though of serious health problems linked to 4F-MPH (or even minor for that matter) and my friend says it's quite a forgiving substance on the body even at the higher dose range, compared to other stimulants (and even pharma drugs which can lead to heavy body stress, jaw clenching etc) not that there's any benefit in doing so really with 4F-MPH. Daily use at least for a week or two, maybe more at lower doses seem well tolerated and normal sleep possible and no negative after effects the next day or over time reported. The only thing to watch is probably blood pressure increase (especially in people with already high blood pressure) and being careful if you have a heart condition, as 4F-MPH definitely increases blood pressure and possibly heart stress more so at higher doses, than many other RC stimulants tried, given its higher potency.
Tagged by Xorkoth
substancecode_4fmethylphenidate
substancecode_4fmph
substancecode_stimulants
explevel_retrospective
exptype_positive
roacode_nasal
This was of interest, because he wanted something that relieved chronic fatigue, provided physical energy and better mental focus. Having tried other RC stimulants and finding them too pleasurable to be used as functional stimulants decided to try 4F-MPH as many reports seemed to indicate it is not pleasurable or euphoric at all, and definitely closer to a medical substance like Adderall etc so more suitable as a work or study aid.
Appearance and characteristics:
Fine white powder, looks very similar to pure cocaine. No smell. Mildly bitter taste. Quite a caustic substance (burns tongue if dissolved in mouth) and if insufflated there is a mild burn, but not too bad due to the very small amounts needed (5-10mg).
4F-MPH is extremely potent and normal dosage is in the range 5-20mg, with 20mg considered a moderate-to-high dose and probably 5-10mg a normal dose. My friend started with a 5mg test dose (insufflated) and found this fairly stimulating and felt more awake, slight mood lift, but nothing remotely pleasurable or euphoric. Basically similar to caffeine, but with a much slower onset (about 30 mins) and a much longer duration of action (about 7-8 hours taken once, 10-14+ hours with 1 re-dose). Higher doses were tried, from 10mg to 30mg, and these only increased the amount of stimulation (and negative side effects), taking the dose higher did not provide any euphoria or anything of recreational value. Even pushing the dose to 100mg in a single day (4 doses spread apart by 3-4 hours) - NOTE this is not advisable and could be dangerous and it did not provide anything remotely close to recreational or pleasurable and only amplified the principle effects of feeling more awake, alert and stimulated into a more uncomfortable zone.
There are no compulsive urges or cravings to re-dose with 4F-MPH like there can be with other RC stimulants. Re-dosing (particularly beyond midday) seems to be wasteful, certainly beyond 1 small re-dose. Sleep became impossible on 4F-MPH with repeated redosing into the afternoon and early evening. Even with the use of benzodiazaphine drugs taken at double a normal knock-out dose, so this gives an idea of the potency and how this substance is very 'cognitive' and very similar to Modafinil in effect (which my friend has tried).
Summary of effects (positive):
- A rather slow onset (30-40 minutes or longer orally) which makes abuse or re-dosing unlikely.
- A more awake state, physical energy and stimulation very similar to caffeine or a pharma drug like Adderall, Modafinil etc.
- Only a fairly small dose needed (10-20mg) once a day in morning, repeated re-dosing only increases the side-effects and duration.
- A very functional stimulant with a very long duration of action (7-8 hours) and no urge to re-dose or abuse.
- A very clear headspace, mind is very focused on whatever task you're doing, no craving for chat or sensory stimulation.
- A mood boost (from increased dopamine) but this is subtle and more like an anti-depressant, rather a coke or amphetamine rush.
- No comedown, quite tolerable to use repeatedly for many days in a row at normal dose range without any ill effects.
Summary of effects (negative):
- Long duration of action, with a long residual physical stimulated feeling which can be unpleasant and make sleep difficult.
- The stimulation feels a little 'forced' particularly at higher doses and can lead to feeling jittery/nervousness or anxiety.
- Affects waking sleep cycle dramatically, especially if taken beyond midday making sleep impossible.
- Substance seems quite caustic (supported by other reports) and can cause mild tissue damage to nasal passages and mouth, plus gastric disturbances.
- Higher doses and/or repeated re-dosing can lead to muscular and cardiovascular tension.
Summary of effects (neutral):
- Appetite suppression, not major though.
- Increased heart rate and blood pressure, again nothing major.
- Flushed face at higher doses, particularly if combined with alcohol.
Any questions, please feel free to ask. My friend has been using this substance now for 2 weeks almost daily at varying doses and has a good feel for the drug and its effects compared to both other RC stimulants (he's tried many so can make comparisons) and also Modafinil and other similar prescription 'smart' drugs, which he has also tried. He says he prefers 4F-MPH over Modafinil and Adderall, as it's not quite as physically stimulating (except at higher doses, i.e. 30+ mg) or prone to causing anxiety as those drugs usually do for him at lower doses relative to 4F-MPH for basically the same level of cognitive and energy boost benefits. As an aside note, seen reports of people also commenting that 4F-MPH may have an anti-depressant use potential, as it lower doses it does seem to act like an anti-depressant acting on dopamine though rather than serotonin, according to the limited scientific info available.
Safety, toxicity & health risks
Finally, please remember as with any RC drugs these effects may be subjective and your experience may be different so start slow with low doses and be careful. Remember this is fairly untested substance in humans, with no clinical trials and a fairly limited history of use in human subjects. The risks and toxicity side of things, particularly longer-term are unknown same as with most RC's, but for short-term and occasional use it seems quite safe. With its potency and a steep dosage-to-effect profile, caution is advised on people with health or heart problems and probably unwise mixing it with other stimulants or drugs, including alcohol beyond light use.
We haven't seen any reports though of serious health problems linked to 4F-MPH (or even minor for that matter) and my friend says it's quite a forgiving substance on the body even at the higher dose range, compared to other stimulants (and even pharma drugs which can lead to heavy body stress, jaw clenching etc) not that there's any benefit in doing so really with 4F-MPH. Daily use at least for a week or two, maybe more at lower doses seem well tolerated and normal sleep possible and no negative after effects the next day or over time reported. The only thing to watch is probably blood pressure increase (especially in people with already high blood pressure) and being careful if you have a heart condition, as 4F-MPH definitely increases blood pressure and possibly heart stress more so at higher doses, than many other RC stimulants tried, given its higher potency.
Tagged by Xorkoth
substancecode_4fmethylphenidate
substancecode_4fmph
substancecode_stimulants
explevel_retrospective
exptype_positive
roacode_nasal
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