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4AceT (4 Acetoxy Tryptamine) Assay

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... that's because the a-Me blocks MAO.
(i'm very sceptical about this bioassay)
 
^Yeah all the straight forward tryptamines in TIHKAL show little effect.

5-Meo-Tryptamine - nothing (although you get melatonin with N-acetyl)

I don't know enough about stability but if (as mentioned above) the acetyl does wander to the amine that would produce a strange melatonin type 4-HO analogue.

Tryptamine - possible effects with high dose IV (but shulgin explains in commentry that what the authors claim to be "LSD syndrome" appears to be more the typical trytamine side effects and is possibily a bad comparison)

N-Methyl-Tryptamine - possible extremely short experience from high dose (only one report though and could easily be placebo)


If 4-Acetoxy-Tryptamine does produce effects - probably not going to follow the typical pattern if at all.
 
I report my findings. Without being precious, it seems a little ingratious for people to be skeptical- As if it were too much of an incalcitrant fact to enter into their finely woven web of worldly belief. Really, is it too much to ask that someone tried something that had an effect that you wouldn't predict? I had hoped to pique people's interest, and I take note that I have piqued the interest of some. But please, skepticism is a tool of ignorance, use it wisely.

I will pander no longer to skeptics on this issue. I enrolled on this forum to disseminate information and interest on this topic and I will shortly be leaving...that is, until I have something of interest to say that no-one else probably will say. At which point I will probably encounter the same pander of top-heavy skeptics.

aloha
 
well there's a reason we're skeptical. This would represent something quite different from other tryptamines that have proven active, and proven inactive.

There's just no way we're going to all jump on your word. That's not how science works.
 
If you know you are correct I see no reason to worry about criticism.

If I had new information on a chemial I would expect criticism & questions - it means the audience is thinking as opposed to being blind ignorant. :)

Important point:

Do you have NMR / GC/MS etc data on this compound? How do you know you ingested 4-Acetoxy-Tryptamine?


People are just making sure this forum is not being subject to any kind of hoax or simple mistake. (Dichloromescaline comes to mind) If what you say is the truth why worry - science is the effort to understand, or to understand better.
 
^word

the attitude of indignation only furthers my skepticism...

"I have too broken the 2nd law of thermodynamics and if you don't believe me you just don't understand."

There are a good number of folks here who can analyze things like this in a professional setting and if you are serious, you would do your best to get in contact with a few to verify the identity of the material.

otherwise i think you have an N-alkylated 4-X tryptamine, which are ubiquitous on the RC market currently...
 
I'll do the oral 25mg 4-HO-NMT bioassay tonight, I am fairly confident its going to be inactive though as oral 10mg 4-HO-NMT was inactive in my friend and I.
 
Just the amount of urine and feces in the trip report make me think this guy is full of shit. WTF?..

gladiolus said:
I report my findings. Without being precious, it seems a little ingratious for people to be skeptical- As if it were too much of an incalcitrant fact to enter into their finely woven web of worldly belief. Really, is it too much to ask that someone tried something that had an effect that you wouldn't predict? I had hoped to pique people's interest, and I take note that I have piqued the interest of some. But please, skepticism is a tool of ignorance, use it wisely.

I will pander no longer to skeptics on this issue. I enrolled on this forum to disseminate information and interest on this topic and I will shortly be leaving...that is, until I have something of interest to say that no-one else probably will say. At which point I will probably encounter the same pander of top-heavy skeptics.aloha
Click to expand...

Yeah, sure dude. Troll?
 
Originally Posted by gladiolus
I report my findings. Without being precious, it seems a little ingratious for people to be skeptical- As if it were too much of an incalcitrant fact to enter into their finely woven web of worldly belief. Really, is it too much to ask that someone tried something that had an effect that you wouldn't predict? I had hoped to pique people's interest, and I take note that I have piqued the interest of some. But please, skepticism is a tool of ignorance, use it wisely.

I will pander no longer to skeptics on this issue. I enrolled on this forum to disseminate information and interest on this topic and I will shortly be leaving...that is, until I have something of interest to say that no-one else probably will say. At which point I will probably encounter the same pander of top-heavy skeptics.aloha
Click to expand...

I dunno about you, but I was always one to pander to top-heavy skeptics. Now that I'm married, not so much. One always dreams, though.

weed always made me feel like I wet myself, especially when I ate it. I'd always look down in fear, expecting a wet spot. Though it was nothing like I assume wetting oneself actually feels like, a very cold feeling, whereas I expect the real thing to be warm and a bit like showering with a t-shirt on.
 
gladiolus said:
I report my findings. Without being precious, it seems a little ingratious for people to be skeptical- As if it were too much of an incalcitrant fact to enter into their finely woven web of worldly belief.
Click to expand...

:p :p
 
samadhi_smiles said:
I'll do the oral 25mg 4-HO-NMT bioassay tonight, I am fairly confident its going to be inactive though as oral 10mg 4-HO-NMT was inactive in my friend and I.
Click to expand...


Updates??
 
5-Meo-Tryptamine - nothing (although you get melatonin with N-acetyl)

I tried this one as a newbie (not like ive got much more experience now, :)) a while back, I dont know if it was just all the codeine I was taking or the fact that a bunch of the product was still melatonin (incomplete reaction, no doubt!), but I felt something.. 'course placebo is never ruled out and is often strong in my case.

He probably isnt lying about what he felt.. he could have been misinformed about what he actually took though. If he made the product himself out of 4-hydroxy tryptamine with a large excess of acetic anhydride he may have ingested the N-acetyl-4-acetoxy derivative instead.

It seems like all of the primary nitrogens in the TiHKAL series have alpha methyl groups though.. shulgin is a smart guy too, I think he may have left out the non methylated tryptamines for a reason *shrug*.. its still possible though, who knows
 
You don't think the N-acetyl-4-acetoxy derivative would be active? I'd imagine some activity, but probably not at the dose he took.

I think it's hard to say why a certain type of alteration was left alone- there's just too many possibilities to be covered in a single book.

I can't find any mention about why those would have been left out explicitly.

He didn't sound like he worked at a lab- do you really think he had access to a acetic anhydride?

I can think of better uses myself, if he did...
 
squerll said:
Just the amount of urine and feces in the trip report make me think this guy is full of shit. WTF?..

Yeah, sure dude. Troll?
Click to expand...

No need to resort to insults ...
 
hammilton- No, I didnt mean to say that at all.. Im saying it could have been active but the drug he took may not have been whatever he thought it was.


He didn't sound like he worked at a lab- do you really think he had access to a acetic anhydride?

I have no idea, its possible to obtain I suppose.. he doesnt say anything though.

I can think of some better uses aswell :)
 
Dondante said:
No need to resort to insults ...
Click to expand...
Sorry just sounds foul when someone takes a shit in the middle of a trip report. And the rest sounded a little trollish . Sorry for the insult.
Carry on.
 
sorry about my last post. I was just flaming a bit about people jumping on the "bullshit" wagon. i am happy really to answer proper questions, of course. I will not reveal my sources, but I did not make it myself. So I guess there is a very slim possibility that I may be mistaken, through misrepresentation, that it was 4AceT. I am willing, if your local laws permit, and this forum permits, that the substance be submitted to analytical testing by someone who can verify it's structure.
I too was struck by these missing structure's in TiKaL!
 
Until there's a confirmation as to the identity of the compound in question, I'm closing this on the grounds that it doesn't fit ant SAR data & seems highly dubious


God, a few days of not editing ADD due to having flu & all these weird threads appear...
 
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