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4-methylamphetamine?

Considering the side effects of mephedrone, which seem very similar in character - although different in magnitude - to what Erny describes about 4-methylamphetamine, I'd definitely be cautious with this substance. After reading Erny's description it should be an easy decision to never ingest the title compound.
 
Refluxer said:
Considering the side effects of mephedrone, which seem very similar in character - although different in magnitude - to what Erny describes about 4-methylamphetamine, I'd definitely be cautious with this substance. After reading Erny's description it should be an easy decision to never ingest the title compound.
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mephedrone is definitely dangerous and heats you up a lot, i personally feel that it has a strong oxidative effetc on omega three oils in the body so when i do lines of it i always rub fish oils into my face and leave on for half an hour to stop the face becomeing dried out. this works wonders=D

but mephedrone is a weakish reuptake inhibitor(its not coaine) but the amphetamine version would likely be a releaser as well and probably wayyyyyyyyyyyyharsher and leave a vicious comedown ie. not worth the pain
 
Fascinating stuff, the idea of p-TAP. Not a good compound, but always impressed that the Russians really go places with their experimenting. I know I'm being overly simplistic, but I've been told that the m-Me analog of mephedrone was much better, so I wonder if m-TAP would be an improvement?
 
fencamfamine said:
Fascinating stuff, the idea of p-TAP. Not a good compound, but always impressed that the Russians really go places with their experimenting. I know I'm being overly simplistic, but I've been told that the m-Me analog of mephedrone was much better, so I wonder if m-TAP would be an improvement?
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According to this study and this study, 3-methylamphetamine was self administered at a higher rate than 4-methylamphetamine in rhesus monkeys (3-fluoroamphetamine and 4-fluoroamphetamine were as well). While all four drugs have similar potencies in releasing dopamine and norepinephrine, they vary in their serotonin releasing properties, with 4-methylamphetamine being strongest serotonin releaser of the bunch (3-fluoroamphetamine was the weakest).

It seems kinda weird to me that multiple 4-substituted amphetamines are known in a recreational context, yet there is apparently very little interest in 3-substituted amphetamines.
 
stirfry said:
According to this study and this study, 3-methylamphetamine was self administered at a higher rate than 4-methylamphetamine in rhesus monkeys (3-fluoroamphetamine and 4-fluoroamphetamine were as well). While all four drugs have similar potencies in releasing dopamine and norepinephrine, they vary in their serotonin releasing properties, with 4-methylamphetamine being strongest serotonin releaser of the bunch (3-fluoroamphetamine was the weakest).

It seems kinda weird to me that multiple 4-substituted amphetamines are known in a recreational context, yet there is apparently very little interest in 3-substituted amphetamines.
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3-FA is one of the strong monoamine releasers known, with DA release greater than that of methamphetamine... which is right from the full text of that study. I think just no one has caught on yet.
 
The few reports on it's effects don't sound fantastic. I've heard a couple of people rave on a about the m-Me analog of MCAT - not that they are totally trustworthy.
 
the trouble with 3-methyl-mcat and 3-ma is the precursors are really difficult too make.

altho 3-fa should be on the market in the coming months, maybe, not sure if he's all that keen on it. lol
 
Pomzazed said:
No it isn't hard at all.
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o i c

not expensive either?

do you mind PM'ing me some clues as too what you mean?

it'd be a straight shoot from the 3-Me-benzaldehyde but...


-_-

maybe its easy for those rich RC vendors with chinese slaves... are you forgetting clandestine chemists still exist?
 
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fencamfamine said:
^I think the Chinese are going via a route that won't give much meta.
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dude theres not alot of routes too 3-methyl-phenyl whatever, you're either aiming for it or your aiming for something else.


3-fluoro is slightly easier, i know that much.

oh and booo!

you're terrible pomzazed:p
quit talking out of your ass
 
^The Chinese use a route that is ever so cheap for the 4-Me, amazingly cheap. I don't think there is such an economical way to the meta analog.
 
^That was a constructive post.

The funny thing is, just about the only 4-monosubstituted PEA that hasn't caused quite a few deaths (for the amount it gets used).

I'm actually more interested in ring-substitutions that don't so much affect subjective effects, but that bring down T1/2. I noted that mephedrone is attacked at the p-Me, but I'm not sure just how much goes that way because it sounds like methcathinone has similar duration...
 
titstypedthis said:
dude theres not alot of routes too 3-methyl-phenyl whatever, you're either aiming for it or your aiming for something else.
3-fluoro is slightly easier, i know that much.
oh and booo!
you're terrible pomzazed:p
quit talking out of your ass
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WTF man? I just stated in chemical point of view that this isn't hard at all!
And plus I just say in one sentence and you say me to stop moaning out of my ass?

Yes, the 3-fluoro is more common hence the corresponding aniline can be displaced via H+/NO2-/F- but not the methyl but that is still NOT my point.

Also, I'm not aiming for it nor aiming for anything at all! the amphetamines and alike are not my style. Meh!

Plus, since when do the precursors here are 'hard to acquire'? the 3-alkylbenzaldehydes, or even 1,3-disub benzene aren't common enought for you?
Oh my ADD these days...
 
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