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4-Hydroxy-5-methoxydimethyltryptamine

Psychonautical

Psychonautical

Bluelighter
Joined
Apr 30, 2008
Messages
952
Location
London Ont
Alright. So i have been growing mushrooms for the past 3 years.
I have just started to achieve some amazing yields. Recently i came across this.
Now i am no chemist, but recently i have been ordering quite a few tryptamines.
Discovering new and uncharted waters inside of my mind.


If i am reading this correctly
http://en.wikipedia.org/wiki/4,5-ho-meo-dmt

by adding 5-meo-dmt to the mushroom substrate, the mushrooms would then in exchange produce a different chemical outside of Psilocybin and Psilocyin.

do not incriminate yourself - nuke

Now i am curious, considering i have access to 5-meo-dmt, but currently, i have on my way, some 5-meo-mipt, also in my possession, i have some 4-aco-dmt.

and if i were to add some of these tryptamines to the substrate,
would that literally be all i'd have to do, to create some mystery mushrooms.

lol, someone needs to explain this process to me, because this has put me into a state of awe.
 
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I don't know about that, but I do know that hmm, what is it...DET and/or one of it's derivatives is a substrate for one of the enzymes in the psilocybin pathway, and that you get 4-ho-det out of your mushrooms via application of det to the substrate.

It's really a question of...is the chemical you add a substrate for one of the enzymes in the psilocybin pathway, if so, then you'll get probably a hydroxylated version of it, if not, the chemical will just be in the mushrooms.

If you were really curious you could get a GC/MS done post hoc and that would tell you which chemicals are present in your fungi.

After reading the link, it seems my info is irrelevant. The papers that discuss this phenomenon probably outline their procedures and those will contain the info that you need. I have journal access so PM me if you don't and I can probably send you the pdf's.
 
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I remember reading a question asked to Dr shulgin about this topic, he said he had an old friend that did some work on this exact topic...I think its worth a try, if you have access to a GC/MS it would be really cool to see results
 
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This idea has been around for ages and still no conclusive results as to whether it works. When I first cultivated mushrooms I thought this was cutting-edge psychonautics and wondered why nobody had tried it given its apparent easiness. Then I found the answer, at least for me: I don't really like 5-MeO-DMT, and in particular a long-acting version of it doesn't appeal to me, and in any case it would already be achievable with the use of MAOIs.

So if you have the opportunity, for God's sake do it already before you lose interest :) A definitive answer has been overdue for years.
 
The biotransformation of unusual tryptamines by Psilocybe species was published by Jochen Gartz (as was mentioned before). The respective refs are:

Journal of Basic Microbiology 1989, 29(6), p.347

Planta Medica 1989, 3, p.249

Peace! Murphy
 
I thought it was quite unlikely to 4-hydroxylate / 4-phosphoryloxylate an already substituted compound due to steric hindred enzyme fitting.
For the same reason I am sceptical about a multisubstituted compound fitting neuroreceptors, or is that ignorant considering the PEA substitution patterns?

In any case I'd bet my money on converting tryptamines that aren't yet substituted e.g. MET --> 4-HO-MET
 
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